Devel­op­ment of fast con­sol­i­dat­ing excip­i­ents as a novel con­cept for the pro­duc­tion of solid dosage forms

Most drugs are processed into tablets by applying pressure. In recent decades, however, research has increasingly focused on 3D printing technologies as a potential alternative to tablet manufacturing. One contribution from our group is the development of pharmaceutical excipients that solidify without pressure simply by adding a few drops of water. This type of ‘water-soluble gypsumr’ enables both a significantly faster production of tablets using 3D powder printing and the pressureless production of pharmaceutical mouldings directly in blister packs.