SFB-F44 - Cell signaling in chronic CNS disorders
Other relevant publications of Ludwig Aigner
2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2003 | 1998 | 1995
2011
Kandasamy M, Reilmann R, Winkler J, Bogdahn U, Aigner L. (2011)
Transforming Growth Factor-Beta Signaling in the Neural Stem Cell Niche: A Therapeutic Target for Huntington's Disease.
Neurol Res Int. 2011;2011:124256. Epub 2011 May 19.
Couillard-Despres S, Vreys R, Aigner L, Van der Linden A. (2011)
In vivo monitoring of adult neurogenesis in health and disease.
Front Neurosci. 2011;5:67. Epub 2011 May 9.
Steffenhagen C, Kraus S, Dechant FX, Kandasamy M, Lehner B, Poehler AM, Furtner T, Siebzehnrubl FA, Couillard-Despres S, Strauss O, Aigner L, Rivera FJ. (2011)
Identity, Fate and Potential of Cells Grown as Neurospheres: Species Matters.
Stem Cell Rev. 2011 Mar 24.
Couillard-Despres S, Aigner L. (2011)
In vivo imaging of adult neurogenesis.
Eur J Neurosci. 2011 Mar;33(6):1037-44. doi: 10.1111/j.1460-9568.2011.07601.x. Review
Couillard-Despres S, Iglseder B, Aigner L. (2011)
Neurogenesis, Cellular Plasticity and Cognition: The Impact of Stem Cells in the Adult and Aging Brain.
Gerontology. 2011 Feb 11.
Ramm P, Bettscheider M, Beier D, Kalbitzer HR, Kremer W, Bogdahn U, Hau P, Aigner L, Beier CP. (2011)
(1)H-Nuclear Magnetic Resonance Spectroscopy of Glioblastoma Cancer Stem Cells.
Stem Cells Dev. 2011 Mar 6.
2010
Zhang J, Giesert F, Kloos K, Vogt Weisenhorn DM, Aigner L, Wurst W, Couillard-Despres S. (2010)
A powerful transgenic tool for fate mapping and functional analysis of newly generated neurons.
BMC Neurosci. 2010 Dec 31;11:158.
Kohl Z, Regensburger M, Aigner R, Kandasamy M, Winner B, Aigner L, Winkler J. (2010)
Impaired adult olfactory bulb neurogenesis in the R6/2 mouse model of Huntington's disease.
BMC Neurosci. 2010 Sep 13;11:114.
Kandasamy M, Couillard-Despres S, Raber KA, Stephan M, Lehner B, Winner B, Kohl Z, Rivera FJ, Nguyen HP, Riess O, Bogdahn U, Winkler J, von Hörsten S, Aigner L. (2010)
Stem Cell Quiescence in the Hippocampal Neurogenic Niche Is Associated With Elevated Transforming Growth Factor-beta Signaling in an Animal Model of Huntington Disease.
J Neuropathol Exp Neurol. 69(7):717-728.
Krampert M, Chirasani SR, Wachs FP, Aigner R, Bogdahn U, Yingling JM, Heldin CH, Aigner L, Heuchel R. (2010)
Smad7 regulates the adult neural stem/progenitor cell pool in a transforming growth factor beta- and bone morphogenetic protein-independent manner.
Mol Cell Biol. 30(14): 3685-94
Rivera FJ., Steffenhagen C., Kremer D., Kandasamy M., Sandner B., Couillard-Despres S., Weidner N., Kuery P., Aigner L. (2010)
Deciphering The Oligodendrogenic Program Of Neural Progenitors: Cell Intrinsic And Extrinsic Regulators.
Stem Cells Dev. 19(5): 595-606.
2009
Wagner K., Couillard-Despres S., Lehner B., Brockhoff G., Rivera FJ., Blume A., Neumann I., Aigner L. (2009)
Prolactin Induces MAPK Signaling in Neural Progenitors without Alleviating Glucocorticoid-Induces Inhibition of in vitro Neurogenesis.
Cell Physiol Biochem; 24:397-406.
Winner B., Desplats P., Hagl C., Klucken J., Aigner R., Ploetz S., Laemke J., Karl A., Aigner L., Masliah E., Buerger E., Winkler J. (2009)
Dopamine receptor activation promotes adult neurogenesis in an acute Parkinson model.
Exp. Neurology 219: 543-552.
Rivera FJ., Siebzehnrubl FA. Kandasamy M., Couillard-Despres S., Caioni M., Poehler AM., Berninger B., Sandner B., Bogdahn U. Goetz M., Bluemke I., Weidner N., Aigner L. (2009)
Mesenchymal Stem Cells Promote Oligodendroglial Differentiation in Hippocampal Slice Cultures.
Cell Physiol. Biochem. 24:317-324.
Stefanova N., Hainer M., Stemberger S., Couillard-Despres S., Aigner L., Poewe W., Wenning G. (2009)
Striatal transplantation for multiple system atrophy – Are grafts affected by alpha-synucleinopathy?
Exp. Neurology 219(1): 368-371.
Couillard-Despres S., Wuertinger C., Kandasamy M., Caioni M., Stadler K., Aigner R., Bogdahn U., Aigner L. (2009)
Ageing Abolishes the Effects of Fluoxetine on Neurogenesis.
Mol. Psychiatry 14(9): 856-864
Torner L., Karg S., Blume A., Kandasamy M., Kuhn H-G., Winkler J., Aigner L., Neumann I. (2009)
Prolactin Prevents Chronic Stress-Induced Decrease of Adult Hippocampal Neurogenesis and Promotes Neuronal Fate.
J. Neuroscience 29(6): 1826-1833
2008
Ramm P, Couillard-Despres S, Plötz S, Rivera FJ, Krampert M, Lehner B, Kremer W, Bogdahn U, Kalbitzer HR, Aigner L. (2008)
A NMR Biomarker for Neural Progenitor Cells: Is It All Neurogenesis?
Stem Cells 2008 Nov 6. [Epub ahead of print].
Rivera FJ, Kandasamy M, Couillard-Despres S, Caioni M, Sanchez R, Huber C, Weidner N, Bogdahn U, Aigner L. (2008)
Oligodendrogenesis of Adult Neural Progenitors: Differential Effects of Ciliary Neurotrophic Factor and Mesenchymal Stem Cell Derived Factors.
J Neurochem. 107(3):832-43.
Mueller AM, Pedré X, Stempfl T, Kleiter I, Couillard-Despres S, Aigner L, Giegerich G, Steinbrecher A. (2008)
Novel role for SLPI in MOG-induced EAE revealed by spinal cord expression analysis.
J Neuroinflammation May 26; 5-20.
Ladewig J, Koch P, Endl E, Meiners B, Opitz T, Couillard-Despres S, Aigner L, Brüstle O. (2008)
Lineage Selection of Functional and Cryopreservable Human Embryonic Stem Cell-Derived Neurons.
Stem Cells. 26(7):1705-12.
Couillard-Després S, Finkl R, Winner B, Ploetz S, Wiedermann D, Aigner R, Bogdahn U, Winkler J, Hoehn M, Aigner L. (2008)
In vivo optical imaging of neurogenesis - Watching new neurons in the intact brain.
Molecular Imaging 7(1); 28-34.
Couillard-Despres S., Quehl E., Karl C., Ploetz S., Bogdahn U., Winkler J., Aigner L. (2008)
In vitro reporter model of neuronal development and early differentiation processes.
BMC Neuroscience. 9: 31.
Winner B., Couillard-Despres S., Geyer M., Aigner R., Bogdahn U., Aigner L., Kuhn G., Winkler J. (2008).
Dopamiergic lesion enhances growh factor-induced striatal neuroblast migration.
J Neuropath Exp Neurol, 67(2): 105-16.
Aigner L. & Bogdahn U. (2008)
TGF-beta in neural stem cells and in tumors of the central nervous system.
Cell Tissue Res. 331(1): 225-41.
2007
Hehr U, Uyanik G, Gross C, Walter MC, Bohring A, Cohen M, Oehl-Jaschkowitz B, Bird LM, Shamdeen GM, Bogdahn U, Schuierer G, Topaloglu H, Aigner L, Lochmuller H, Winkler J (2007)
Novel POMGnT1 mutations define broader phenotypic spectrum of muscle-eye-brain disease.
Neurogenetics. 8(4): 279-88.
Beier, D., Hau, P., Proescholdt, M., Lohmeier, A., Wischhusen, J., Oefner, P.J., Aigner, L., Brawanski, A., Bogdahn, U. & Beier, C.P. (2007)
CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles.
Cancer Res, 67: 4010-4015.
Kohl, Z., Kandasamy, M., Winner, B., Aigner, R., Gross, C., Couillard-Despres, S., Bogdahn, U., Aigner, L. & Winkler, J. (2007)
Physical activity fails to rescue hippocampal neurogenesis deficits in the R6/2 mouse model of Huntington's disease.
Brain Res, 1155: 24-33.
Uyanik, G., Morris-Rosendahl, D.J., Stiegler, J., Klapecki, J., Gross, C., Berman, Y., Martin, P., Dey, L., Spranger, S., Korenke, G.C., Schreyer, I., Hertzberg, C., Neumann, T.E., Burkart, P., Spaich, C., Meng, M., Holthausen, H., Ades, L., Seidel, J., Mangold, E., Buyse, G., Meinecke, P., Schara, U., Zeschnigk, C., Muller, D., Helland, G., Schulze, B., Wright, M.L., Kortge-Jung, S., Hehr, A., Bogdahn, U., Schuierer, G., Kohlhase, J., Aigner, L., Wolff, G., Hehr, U. & Winkler, J. (2007)
Location and type of mutation in the LIS1 gene do not predict phenotypic severity.
Neurology, 69: 442-447.
2006
Couillard-Despres S., Winner B., Karl C., Lindemann G., Schmid P., Aigner R., Laemke J., Bogdahn U., Winkler J., Bischofberger J., Aigner L. (2006).
Targeted transgene expression in neuronal precursors: watching young neurons in the old brain.
European Journal of Neuroscience. 24(6): 1535-45.
Rivera F., Couillard-Despres S., Pedre-Villareal X., Ploetz S., Lois C., Bogdahn U., Aigner L. (2006).
Mesenchymal stem cells instruct oligodendrogenic fate decision on adult neural stem cells.
Stem Cells. 24(10): 2209-19.
Rivera F., Sierralta W.D., Minguell J., Aigner L. (2006).
Adult hippocampus derived soluble factors induce a neuronal-like phenotype in mesenchymal stem cells.
Neuroscience Letters. 406: 49-54.
Pfeifer K., Vroemen M., Caioni M., Aigner L., Bogdahn U., Weidner N. (2006).
Autologous adult neural progenitor cell transplantation represents a feasible strategy to promote structural repair in the chronically injured spinal cord.
Regenerative Medicine. 1(2): 255-66.
Wachs F.-P., Winner B., Couillard-Despres S., Schiller T., Aigner R., Winkler J., Bogdahn U., and Aigner L. (2006).
Transforming growth factor-b1 is a negative modulator of adult neurogenesis.
J. Neuropath. Exp. Neurol. 65(4): 358-70.
Winner B., Geyer M., Couillard-Despres S., Aigner R., Bogdahn U., Aigner L., Kuhn G., Winkler J. (2006).
Striatal deafferentation increases dopaminergic neurogenesis in the adult olfactory bulb.
Exp Neurol. 197: 113-21.
2005
Engelhardt M., Bogdahn U., Aigner L. (2005).
Adult retinal pigment epithelium cells express neural progenitor properties and the neuronal precursor protein doublecortin.
Brain Res, 1040: 98-111.
Couillard-Despres S., Winner B., Schaubeck S., Aigner R., Vroemen M., Weidner N., Bogdahn U., Winkler J., Kuhn H.-G., Aigner L. (2005).
Doublecortin expression levels in adult brain reflect neurogenesis.
Eur. J. Neurosci, 21: 1-14.
Karl C., Couillard-Despres S., Prang P., Munding M., Kilb W., Brigadski T., Plötz S., Mages W., Luhmann H., Winkler J., Bogdahn U., Aigner L. (2005).
Neuronal precursor specific activity of a human doublecortin regulatory sequence.
J. Neurochem, 92: 264-282.
2003
Vroemen M., Aigner L., Winkler J., Weidner N. (2003).
Adult neural progenitor cell grafts survive after acute spinal cord injury and integrate into axonal pathways.
European Journal of Neuroscience, 18: 743-51.
Brown J., Couillard-Despres S., Cooper-Kuhn C., Winkler J., Aigner L., Kuhn H.-G. (2003).
Transient expression of doublecortin during adult neurogenesis.
Journal of Comparative Neurology, 467: 1-10.
Wachs F.-P., Couillard-Despres S., Engelhardt M., Wilhelm D., Ploetz S., Vroemen M., Kaesbauer J., Uyanik G., Klucken J., Karl C., Tebbing J., Svendsen C.N., Weidner N., Kuhn H.-G., Winkler J., Aigner L. (2003).
High efficacy of clonal growth and expansion of adult neural stem cells.
Lab. Invest., 83: 949-962.
1998
Di Polo A.*, Aigner L. *, Dunn R.J., Bray G.M., Aguayo A.J. (1998).
Prolonged delivery of brain-derived neurotrophic factor by adenovirus-infected Müller cells temporarily rescues injured retinal ganglion cells.
Proc. Natl. Acad. Sci. USA, 95: 3978-3983. *: equal contribution
1995
Aigner L., Arber S., Kapfhammer J. P., Laux T., Schneider C., Botteri F., Brenner H.-R., Caroni P. (1995).
Overexpression of the neural growth-associated protein GAP-43 induces nerve sprouting in the adult nervous system of transgenic mice.
Cell, 83: 269-278.
