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Publikationen – Universität Innsbruck

Publikationen 2024

(Mit-)Herausgeberschaft von Periodika / Buchreihen

Herausgeberschaft von Periodikum / Buchreihe
  • Finotello, Francesca: Associate Editor - Molecular & Cellular Oncology, 01.01.2021 lfd. (Weblink)

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)
  • Benjamin-Zukerman, Tal; Shimon, Gilat; Gaine, Marie E; Dakwar, Anwar; Peled, Netta; Aboraya, Mohammad; Masri-Ismail, Ashar; Safadi-Safa, Rania; Solomon, Meir; Lev-Ram, Varda; Rissman, Robert A; Mayrhofer, Johanna E; Raffeiner, Andrea; Mol, Merel O; Argue, Benney MR; McCool, Shaylah; Doan, Binh; Van Swieten, John; Stefan, Eduard; Abel, Ted; Ilouz, Ronit (First View): A mutation in the PRKAR1B gene drives pathological mechanisms of neurodegeneration across species.
    In: Brain. (DOI) (Weblink)

  • Costacurta, Francesco; Dodaro, Andrea; Bante, David; Schöppe, Helge; Peng, Ju-Yi; Sprenger, Bernhard; He, Xi; Moghadasi, Seyed Arad; Egger, Lisa Maria; Fleischmann, Jakob; Pavan, Matteo; Bassani, Davide; Menin, Silvia; Rauch, Stefanie; Krismer, Laura; Sauerwein, Anna; Heberle, Anne; Rabensteiner, Toni; Ho, Joses; Harris, Reuben S.; Stefan, Eduard; Schneider, Rainer; Dunzendorfer-Matt, Theresia; Naschberger, Andreas; Wang, Dai; Kaserer, Teresa; Moro, Stefano; von Laer, Dorothee; Heilmann, Emmanuel (2024): A comprehensive study of SARS-CoV-2 main protease (Mpro) inhibitor-resistant mutants selected in a VSV-based system.
    In: PLoS Pathogens 20/9, No. e1012522. (DOI) (Weblink)

  • Feichtner, Andreas; Enzler, Florian; Kugler, Valentina; Hoppe, Katharina; Mair, Sophia; Kremser, Leopold; Lindner, Herbert; Huber, Roland G.; Stelzl, Ulrich; Stefan, Eduard; Torres-Quesada, Omar (2024): Phosphorylation of the compartmentalized PKA substrate TAF15 regulates RNA-protein interactions.
    In: Cellular and Molecular Life Sciences 81/1, No. 162. (DOI) (Weblink)

  • Fiegl, Manuel; Kimmel, Robin A. (2024): Laboratory Course Using Zebrafish to Uncover Changing Roles of Wnt Signaling in Early Vertebrate Development.
    In: Zebrafish 21/2, S. 128 - 136. (DOI) (Weblink)

  • Frank, Sarah; Gabassi, Elisa; Käseberg, Stephan; Bertin, Marco; Zografidou, Lea; Pfeiffer, Daniela; Brennenstuhl, Heiko; Falk, Sven; Karow, Marisa; Schweiger, Susann (2024): Absence of the RING domain in MID1 results in patterning defects in the developing human brain.
    In: Life Science Alliance 7/4, Nr. e202302288. (DOI) (Weblink)

  • Heimdörfer, David; Vorleuter, Alexander; Eschlböck, Alexander; Spathopoulou, Angeliki; Suarez-Cubero, Marta; Farhan, Hesso; Reiterer, Veronika; Spanjaard, Melanie; Schaaf, Christian P.; Huber, Lukas A.; Kremser, Leopold; Sarg, Bettina; Edenhofer, Frank; Geley, Stephan; de Araujo, Mariana EG; Huettenhofer, Alexander (2024): Truncated variants of MAGEL2 are involved in the etiologies of the Schaaf-Yang and Prader-Willi syndromes.
    In: AMERICAN JOURNAL OF HUMAN GENETICS 111/7, S. 1383 - 1404. (DOI) (Weblink)

  • Hoppe, Nicholas; Harrison, Simone; Hwang, SH; Chen, Ziwei; Karelina, Masha; Deshpande, Ishan; Suomivuori, CM; Palicharla, VR; Berry, SP; Tschaikner, Philipp; Regele, Dominik; Covey, DF; Stefan, Eduard; Marks, Deborah S; Reiter, Jeremy F; Dror, RO; Evers, AS; Mukhopadhyay, Saikat; Manglik, Aashish (2024): GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway.
    In: Nature structural & molecular biology 31/4, S. 667 - 677. (DOI) (Weblink)

  • Höpperger, Sabrina; Spathopoulou, Angeliki; Mayer-Suess, Lukas; Suarez-Cubero, Marta; Sillaber, Katharina; Spreiz, Ana; Kiechl, Stefan; Edenhofer, Frank; Fellner, Lisa (2024): Generation of the human induced pluripotent stem cell line (IBKMOLi003-A) from PBMCs of a vascular Ehlers-Danlos syndrome (vEDS) patient carrying the heterozygous nonsense mutation c.430C > T (p.Q105*) in the COL3A1 gene.
    In: Stem Cell Research 75, Nr. 103321. (DOI) (Weblink)

  • Hornsteiner, F.; Vierthaler, J.; Strandt, H.; Resag, A.; Fu, Z.; Ausserhofer, M.; Tripp, C.H.; Dieckmann, S.; Kanduth, M.; Farrand, K.; Bregar, S.; Nemati, N.; Hermann-Kleiter, N.; Seretis, Athanasios; Morla, S.; Mullins, D.; Finotello, F.; Trajanoski, Z.; Wollmann, G.; Ronchese, F.; Schmitz, M.; Hermans, I.F.; Stoitzner, P. (2024): Tumor-targeted therapy with BRAF-inhibitor recruits activated dendritic cells to promote tumor immunity in melanoma.
    In: Journal for ImmunoTherapy of Cancer 12/4, No. e008606. (DOI) (Weblink)

  • Juen, Fabian; Glänzer, David; Plangger, Raphael; Kugler, Valentina; Fleischmann, Jakob; Stefan, Eduard; Case, David A; Kovacs, Helena; Kwaku Dayie, Theodore; Kreutz, Christoph (2024): Enhanced TROSY Effect in [ 2-19F, 2-13C] Adenosine and ATP Analogs Facilitates NMR Spectroscopy of Very Large Biological RNAs in Solution.
    In: Angewandte Chemie International Edition 63/9, No. e202316273. (DOI) (Weblink)

  • Kalla, C; Ott, G; Finotello, F; Niewola-Staszkowska, K; Conza, GD; Lahn, M; van der Veen, L; Schüler, J; Falkenstern-Ge, R; Kopecka, J; Riganti, C (2024): The highly selective and oral phosphoinositide 3-kinase delta (PI3K-δ) inhibitor roginolisib induces apoptosis in mesothelioma cells and increases immune effector cell composition.
    In: Translational Oncology 43, No. 101857. (DOI) (Weblink)

  • Kinget, L; Naulaerts, S; Govaerts, J; Vanmeerbeek, I; Sprooten, J; Laureano, RS; Dubroja, N; Shankar, G; Bosisio, FM; Roussel, E; Verbiest, A; Finotello, F; Ausserhofer, M; Lambrechts, D; Boeckx, B; Wozniak, A; Boon, L; Kerkhofs, J; Zucman-Rossi, J; Albersen, M; Baldewijns, M; Beuselinck, B; Garg, AD (2024): A spatial architecture-embedding HLA signature to predict clinical response to immunotherapy in renal cell carcinoma.
    In: NATURE MEDICINE 30/6, S. 1667 - 1679. (DOI) (Weblink)

  • Kugler, Valentina; Schwaighofer, Selina; Feichtner, Andreas; Enzler, Florian; Fleischmann, Jakob; Strich, Sophie; Schwarz, Sarah; Wilson, Rebecca; Tschaikner, Philipp; Troppmair, Jakob; Sexl, Veronika; Meier, Pascal; Kaserer, Teresa; Stefan, Eduard (2024): Impact of protein and small molecule interactions on kinase conformations.
    In: eLife 13, Nr. RP94755. (DOI) (Weblink)

  • Lapuente-Santana, Óscar; Sturm, Gregor; Kant, Joan; Ausserhofer, Markus; Zackl, Constantin; Zopoglou, Maria; McGranahan, Nicholas; Rieder, Dietmar; Trajanoski, Zlatko; da Cunha Carvalho de Miranda, Noel Filipe; Eduati, Federica; Finotello, Francesca (2024): Multimodal analysis unveils tumor microenvironment heterogeneity linked to immune activity and evasion.
    In: iScience 27/8, No. 110529. (DOI) (Weblink)

  • Lindenhofer, Dominik; Haendeler, Simon; Esk, Christopher; Littleboy, Jamie B.; Avalos, Clarisse Brunet; Naas, Julia; Pflug, Florian G.; van der Ven, Eline GP; Reumann, Daniel; Baffet, Alexandre D.; von Haeseler, Arndt; Knoblich, Jürgen (2024): Cerebral organoids display dynamic clonal growth and tunable tissue replenishment.
    In: Nature Cell Biology 26, S. 710 - 718. (DOI) (Weblink)

  • Mason, M; Lapuente-Santana, Ó; Halkola, AS; Wang, W; Mall, R; Xiao, X; Kaufman, J; Fu, J; Pfeil, J; Banerjee, J; Chung, V; Chang, H; Chasalow, SD; Lin, HY; Chai, R; Yu, T; Finotello, F; Mirtti, T; Mäyränpää, MI; Bao, J; Verschuren, EW; Ahmed, EI; Ceccarelli, M; Miller, LD; Monaco, G; Hendrickx, WRL; Sherif, S; Yang, L; Tang, M; Gu, SS; Zhang, W; Zhang, Y; Zeng, Z; Das Sahu, A; Liu, Y; Yang, W; Bedognetti, D; Tang, J; Eduati, F; Laajala, TD; Geese, WJ; Guinney, J; Szustakowski, JD; Vincent, BG; Carbone, DP (2024): A community challenge to predict clinical outcomes after immune checkpoint blockade in non-small cell lung cancer.
    In: Journal of Translational Medicine 22/1, S. No 190. (DOI) (Weblink)

  • Merotto, Lorenzo; Sturm, Gregor; Dietrich, Alex; List, Markus; Finotello, Francesca (2024): Making mouse transcriptomics deconvolution accessible with immunedeconv.
    In: Bioinformatics Advances 4/1, Nr. vbae032. (DOI) (Weblink)

  • Merotto, Lorenzo; Zopoglou, Maria; Zackl, Constantin; Finotello, Francesca (2024): Next-generation deconvolution of transcriptomic data to investigate the tumor microenvironment.
    In: International Review of Cell and Molecular Biology 382, S. 103 - 143. (DOI) (Weblink)

  • Meyer, Katharina; Ling, King-Hwa; Yeo, Pei-Ling; Spathopoulou, Angeliki; Drake, Derek; Choi, Jaejoon; Aron, Liviu; Garcia-Corral, Mariana; Ko, Tak; Lee, Eunjung Alice; Tam, Jenny M.; Perlis, Roy H.; Church, George M.; Tsai, Li-Huei; Yankner Bruce A. (2024): Impaired neural stress resistance and loss of REST in bipolar disorder.
    In: Molecular Psychiatry 29/1, S. 153 - 164. (DOI) (Weblink)

  • Pflug, Florian G.; Haendeler, Simon; Esk, Christopher; Lindenhofer, Dominik; Knoblich, Jürgen A.; von Haeseler, Arndt (2024): Neutral competition explains the clonal composition of neural organoids.
    In: PLoS Computational Biology 20/4, Nr. e1012054. (DOI) (Weblink)

  • Spathopoulou, Angeliki; Podlesnic, Martina; De Gaetano, Laura; Kirsch, Elena Marie; Tisch, Marcel; Finotello, Francesca; Aigner, Ludwig; Günther, Katharina; Edenhofer, Frank (2024): Single-cell Profiling of Reprogrammed Human Neural Stem Cells Unveils High Similarity to Neural Progenitors in the Developing Central Nervous System.
    In: Stem Cell Reviews and Reports 20/5, S. 1325 - 1339. (DOI) (Weblink)

  • Spathopoulou, Angeliki; Sauerwein, Gabriella A.; Marteau, Valentin; Podlesnic, Martina; Lindlbauer, Theresa; Kipura, Tobias; Hotze, Madlen; Gabassi, Elisa; Kruszewski, Katharina; Koskuvi, Marja; Réthelyi, János M.; Apáti, Ágota; Conti, Luciano; Ku, Manching; Koal, Therese; Müller, Udo; Talmazan, Radu A.; Ojansuu, Ilkka; Vaurio, Olli; Lähteenvuo, Markku; Lehtonen, Šárka; Mertens, Jerome; Kwiatkowski, Marcel; Günther, Katharina; Tiihonen, Jari; Koistinaho, Jari; Trajanoski, Zlatko; Edenhofer, Frank (2024): Integrative metabolomics-genomics analysis identifies key networks in a stem cell-based model of schizophrenia.
    In: Molecular Psychiatry 29, S. 3128 - 3140. (DOI) (Weblink)

Zeitschriftenaufsatz (Review)
  • Beirute-Herrera, Julianne; Calvo, Beatriz López-Amo; Edenhofer, Frank; Esk, Christopher (2024): The promise of genetic screens in human in vitro brain models.
    In: BIOLOGICAL CHEMISTRY 405/1, S. 13 - 24. (DOI) (Weblink)

Forschungsdaten

  • Dietrich, Alexander; Merotto, Lorenzo; Pelz, Konstantin; Eder, Bernhard; Zackl, Constantin; Reinisch, Katharina; Marini, Federico; Sturm, Gregor; List, Markus; Finotello, Francesca (2024): deconvBench (Datensatz). Version 1. In: GitHub. (Weblink)

  • Zackl, Constantin; Dietrich, Alexander; Merotto, Lorenzo; Pelz, Konstantin; Eder, Bernhard; Reinisch, Katharina; Marini, Federico; Sturm, Gregor; List, Markus; Finotello, Francesca (2021-2024): deconvExplorer (Software). Version 1. In: GitHub. (Weblink)



Publikationen 2023

(Mit-)Herausgeberschaft von Periodika / Buchreihen

Herausgeberschaft von Periodikum / Buchreihe
  • Finotello, Francesca: Associate Editor - Molecular & Cellular Oncology, 01.01.2021 lfd. (Weblink)

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)
  • Baruzzo, Giacomo; Serafini, Agnese; Finotello, Francesca; Sanavia, Tiziana; Cioetto-Mazzabò, Laura; Boldrin, Francesca; Lavezzo, Enrico; Barzon, Luisa; Toppo, Stefano; Provvedi, Roberta; Manganelli, Riccardo; Di Camillo, Barbara (2023): Role of the Extracytoplasmic Function Sigma Factor SigE in the Stringent Response of Mycobacterium tuberculosis.
    In: Microbiology Spectrum 11/2, No. e0294422. (DOI) (Weblink)

  • Borras, D. M.; Verbandt, S.; Ausserhofer, M.; Sturm, G.; Lim, J.; Verge, G. A.; Vanmeerbeek, I.; Laureano, R. S.; Govaerts, J.; Sprooten, J.; Hong, Y.; Wall, R.; De Hertogh, G.; Sagaert, X.; Bislenghi, G.; D'Hoore, A.; Wolthius, A.; Finotello, F.; Park, W.-Y.; Naulerts, S.; Tejpar, S.; Garg, A. D. (2023): Single cell dynamics of tumor specificity vs bystander activity in CD8+ T cells define the diverse immune landscapes in colorectal cancer.
    In: Cell Discovery 9, Nr. 114. (DOI) (Weblink)

  • Fleischmann, Jakob; Schwaighofer, Selina; De Falco, Louis; Enzler, Florian; Feichtner, Andreas; Kugler, Valentina; Tschaikner, Philipp; Huber, Roland G.; Stefan, Eduard (2023): Tracking and blocking interdependencies of cellular BRAF-MEK oncokinase activities.
    In: PNAS Nexus 2/6, Nr. pgad185. (DOI) (Weblink)

  • Freudenblum, Julia; Meyer, Dirk; Kimmel, Robin A. (2023): Mitochondrial network expansion and dynamic redistribution during islet morphogenesis in zebrafish larvae.
    In: FEBS Letters 597/2, S. 262 - 275. (DOI) (Weblink)

  • Gollmann-Tepeköylü, Can; Graber, Michael; Hirsch, Jakob; ..., ...; Töchterle, Sonja; ..., ...; Meyer, Dirk; et al. (2023): Toll-Like Receptor 3 Mediates Aortic Stenosis Through a Conserved Mechanism of Calcification.
    In: Circulation 147/20, S. 1518 - 1533. (DOI) (Weblink)

  • Kugler, Valentina; Lieb, Andreas; Guerin, Nathan; Donald, Bruce R.; Stefan, Eduard; Kaserer, Teresa (2023): Computational identification of oncogenic mutants disrupting protein interactions.
    In: Communications Biology 6, Nr. 720. (DOI) (Weblink)

  • Li, Chong; Fleck, Jonas Simon; Martins-Costa, Catarina; Burkard, Thomas R.; Themann, Jan; Stuempflen, Marlene; Angela Maria, Peer; Vertesy, Ábel; Littleboy, Jamie B.; Esk, Christopher; Elling, Ulrich; Kasprian, Gregor; Corsini, Nina S.; Treutlein, Barbara; Knoblich, Juergen A. (2023): Single-cell brain organoid screening identifies developmental defects in autism.
    In: Nature 621, S. 373 - 380. (DOI) (Weblink)

  • Moesslacher, Christina S; Auernig, Elisabeth; Woodsmith, Jonathan; Feichtner, Andreas; Jany-Luig, Evelyne; Jehle, Stefanie; Worseck, Josephine M.; Heine, Christian L.; Stefan, Eduard; Stelzl, Ulrich (2023): Missense variant interaction scanning reveals a critical role of the FERM domain for tumor suppressor protein NF2 conformation and function.
    In: Life Science Alliance 6/8, Nr. e202302043. (DOI) (Weblink)

  • Plattner, C.; Lamberti, G.; Blattmann, P.; Kirchmair, A.; Rieder, D.; Loncova, Z.; Sturm, G.; Scheidl, S.; Ijsselsteijn, M.; Fotakis, G.; Noureen, A.; Lisandrelli, R.; Böck, N.; Nemati, N.; Krogsdam, A.; Daum, S.; Finotello, F.; Somarakis, A.; Schäfer, A.; Wilflingseder, D.; Trojanoski, Z. (2023): Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer.
    In: iScience 26/12, Nr. 108399. (DOI) (Weblink)

Zeitschriftenbeitrag (anderer)
  • Virshup, Isaac; Bredikhin, Danila; Heumos, Lukas; Palla, Giovanni; Sturm, Gregor; Gayoso, Adam; Kats, Ilia; Koutrouli, Mikaela; Community, Scverse; Berger, Bonnie; Pe'er, Dana; Regev, Aviv; Teichmann, Sarah A; Finotello, Francesca; Wolf, Alexander; Yosef, Nir; Stegle, Oliver; Theis, Fabian J (2023): The scverse project provides a computational ecosystem for single-cell omics data analysis.
    In: Nature Biotechnology 41/5, S. 604 - 606. (DOI) (Weblink)

Forschungsdaten

  • Ausserhofer, Markus; Rieder, Dietmar; Finotello, Francesca (2023): NovumRNA: A non-canonical tumor specific antigen prediction pipeline (Software). Version v. 1.0.0. In: GitHub. (Weblink)

  • Zackl, Constantin; Dietrich, Alexander; Merotto, Lorenzo; Pelz, Konstantin; Eder, Bernhard; Reinisch, Katharina; Marini, Federico; Sturm, Gregor; List, Markus; Finotello, Francesca (2021-2024): deconvExplorer (Software). Version 1. In: GitHub. (Weblink)



Publikationen 2022

(Mit-)Herausgeberschaft von Periodika / Buchreihen

Herausgeberschaft von Periodikum / Buchreihe
  • Finotello, Francesca: Associate Editor - Molecular & Cellular Oncology, 01.01.2021 lfd. (Weblink)

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)
  • Abdulrahman, Ziena; Santegoets, Saskia J; Sturm, Gregor; Charoentong, Pornpimol; IJsselsteijn, Marieke E; Somarakis, Antonios; Höllt, Thomas; Finotello, Francesca; Trajanoski, Zlatko; van Egmond, Sylvia L; Mustafa, Dana A M; Welters, Marij J P; de Miranda, Noel F C C; van der Burg, Sjoerd H (2022): Tumor specific T cells support chemokine-driven spatial organization of intratumoral immune microaggregates needed for long survival.
    In: Journal for ImmunoTherapy of Cancer 10/2, No. e004346. (DOI) (Weblink)

  • Böhnke, L.; Zhou-Yang, L.; Pelucchi, S.; Kogler, F.; Frantal, D.; Schön, F.; Lagerström, S.; Borgogno, O.; Baltazar, J.; Herdy, J. R.; Kittel-Scheider, S.; Defrancesco, M.; Mertens, J. (2022): Chemical Replacement of Noggin with Dorsomorphin Homolog 1 for Cost-Effective Direct Neuronal Conversion.
    In: Cellular Reprogramming 24/5, S. 304 - 313. (DOI) (Weblink)

  • Borst, Linda; Sluijter, Marjolein; Sturm, Gregor; Charoentong, Pornpimol; Santegoets, Saskia J.; van Gulijk, Mandy; van Elsas, Marit J; Groeneveldt, Christianne; van Montfoort, Nadine; Finotello, Francesca; Trajanoski, Zlatko; Kiełbasa, Szymon M; van der Burg, Sjoerd H.; van Hall, Thorbald (2022): NKG2A is a late immune checkpoint on CD8 T cells and marks repeated stimulation and cell division.
    In: International Journal of Cancer 150/4, S. 688 - 704. (DOI) (Weblink)

  • Cesaro, G.; Milia, M.; Baruzzo, G.; Finco, G.; Morandini, F.; Lazzarini, A.; Alotto, P.; da Cunha Carvalho de Miranda, N. F.; Trajanoski, Z.; Finotello, F.; Di Camillo, B (2022): MAST: a hybrid Multi-Agent Spatio-Temporal model of tumor microenvironment informed using a data-driven approach.
    In: Bioinformatics Advances 2/1, Nr. vbac092. (DOI) (Weblink)

  • Dietrich, Alexander; Sturm, Gregor; Merotto, Lorenzo; Marini, Federico; Finotello, Francesca; List, Markus (2022): SimBu: bias-aware simulation of bulk RNA-seq data with variable cell-type composition.
    In: Bioinformatics 38/Supplement_2, S. ii141 - ii147. (DOI) (Weblink)

  • Duurland, Chantal L; Santegoets, Saskia J; Abdulrahman, Ziena; Loof, Nikki M; Sturm, Gregor; Wesselink, Tom H; Arens, Ramon; Boekestijn, Sann; Ehsan, Ilina; van Poelgeest, Mariette I E; Finotello, Francesca; Hackl, Hubert; Trajanoski, Zlatko; ten Dijke, Peter; Braud, Veronique M; Welters, Marij J P; van der Burg, Sjoerd H (2022): CD161 expression and regulation defines rapidly responding effector CD4+ T 2 cells associated with improved survival in HPV16-associated tumors.
    In: Journal for ImmunoTherapy of Cancer 10/1, No. e003995. (DOI) (Weblink)

  • Garcia, G.; Pinto, S.; Ferreira, S.; Lopes, D.; ..., ...; Edenhofer, F.; ..., ...; Brites, D. (2022): Emerging Role of miR-21-5p in Neuron-Glia Dysregulation and Exosome Transfer Using Multiple Models of Alzheimer's Disease.
    In: Cells 11/21, Nr. 3377. (DOI) (Weblink)

  • Graber, M; Nägel, F; Röhrs, BT; Hirsch, J; Pölzl, L; Moriggl, B; Mayr, A; Troger, F; Kirchmair, E; Wagner, JF; Nowosielski, M; Mayer, L; Voelkl, J; Tancevski, I; Meyer, D; Grimm, M; Knoflach, M; Holfeld, J; Gollmann-Tepeköylü, Can (2022): Prevention of Oxidative Damage in Spinal Cord Ischemia Upon Aortic Surgery: First‐In‐Human Results of Shock Wave Therapy Prove Safety and Feasibility.
    In: Journal of the American Heart Association 11/20, Nr. e026076. (DOI) (Weblink)

  • Herdy, J. R.; Traxler, L.; Agarwal, R. K.; Karbacher, L.; Schlachetzki, J. C. M.; Boehnke, L.; Zangwill, D.; Galasko, D.; Glass, C. K.; Mertens, J.; Gage, F. H. (2022): Increased post-mitotic senescence in aged human neurons is a pathological feature of Alzheimer’s disease.
    In: Cell Stem Cell 29/12, S. 1637 - 1652. (DOI) (Weblink)

  • Radtke, F.; Palladino, V. S.; McNeill, R.; ..., ...; Edenhofer, F.; ..., ...; Kittel-Schneider, S. (2022): ADHD-associated PARK2 copy number variants: A pilot study on gene expression and effects of supplementary deprivation in patient-derived cell lines.
    In: AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS 189/7-8, S. 257 - 270. (DOI) (Weblink)

  • Rieder, Dietmar; Fotakis, Georgios; Ausserhofer, Markus; Geyeregger, René; Paster, Wolfgang; Trajanoski, Zlatko; Finotello, Francesca (2022): nextNEOpi: a comprehensive pipeline for computational neoantigen prediction.
    In: Bioinformatics 38/4, S. 1131 - 1132. (DOI) (Weblink)

  • Rufo, Nicole; Korovesis, Dimitris; Van Eygen, Sofie; Derua, Rita; Garg, Abhishek D; Finotello, Francesca; Vara-Perez, Monica; Rožanc, Jan; Dewaele, Michael; de Witte, Peter A; Alexopoulo, Leonidas G; Janssens, Sophie; Sinkkonen, Lasse; Sauter, Thomas; Verhelst, Steven HL; Agostinis, Patrizia (2022): Stress-induced inflammation evoked by immunogenic cell death is blunted by the IRE1α kinase inhibitor KIRA6 through HSP60 targeting.
    In: Cell Death and Differentiation 29/1, S. 230 - 245. (DOI) (Weblink)

  • Salcher, Stefan; Sturm, Gregor; Horvath, Lena; Untergasser, Gerold; Kuempers, Christiane; Fotakis, Georgios; Panizzolo, Elisa; Martowicz, Agnieszka; Trebo, Manuel; Pall, Georg; Gamerith, Gabriele; Sykora, Martina; Augustin, Florian; Schmitz, Katja; Finotello, Francesca; Rieder, Dietmar; Perner, Sven; Sopper, Sieghart; Wolf, Dominik; Pircher, Andreas; Trajanoski, Zlatko (2022): High-resolution single-cell atlas reveals diversity and plasticity of tissue-resident neutrophils in non-small cell lung cancer.
    In: Cancer Cell 40/12, S. 1503 - 1520. (DOI) (Weblink)

  • Tisch, M.; Alemany, MCD; Suarez-Cubero, M; ..., ...; Günther, K; Edenhofer, F (2022): Generation of the human induced pluripotent stem cell line (IBKMOLi002-A) from PBMCs of a patient carrying the heterozygous L271H mutation of the voltage-gated calcium channel subunit Ca(v)1.3-encoding CACNA1D gene.
    In: Stem Cell Research 61, Nr. 102784. (DOI) (Weblink)

  • Traxler, L.; Herdy, J. R.; Stefanoni, D.; Eichhorner, S.; Pelucchi, S.; Szucs, A.; Santagostino, A.; Kim, Y.; ..., ...; Lagerwall, J.; ..., ...; Mertens, J. (2022): Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer's disease.
    In: Cell Metabolism 34/9, S. 1248 - 1263. (DOI) (Weblink)

  • van den Hurk, M.; Lau, S.; Merchetto, M. C.; Mertens, J.; Stern, S.; Corti, O.; Brice, A.; Winner, B.; Winkler, J.; Gage, F. H.; Bardy, C. (2022): Druggable transcriptomic pathways revealed in Parkinson's patient-derived midbrain neurons.
    In: npj Parkinsons Disease 8/1, Nr. 134. (DOI) (Weblink)

Zeitschriftenaufsatz (Review)
  • Spathopoulou, A.; Edenhofer, F.; Fellner, L. (2022): Targeting alpha-Synuclein in Parkinson's Disease by Induced Pluripotent Stem Cell Models.
    In: Frontiers in Neurology 12, Nr. 786835. (DOI) (Weblink)

Zeitschriftenbeitrag (anderer)
  • Greiff, Victor; Luning Prak, Eline T; O'Donnell, Tim; Finotello, Francesca; Reddy, Sai T; Walczak, Aleksandra; Mora; Thierry (2022): What are the current driving questions in immune repertoire research?
    In: Cell Systems 13/9, S. 683 - 686. (DOI) (Weblink)

Forschungsdaten

  • Dietrich, Alexander; Sturm, Gregor; Merott, Lorenzo; Marini, Federico; Finotello, Francesca; List, Markus (2022): SimBu. Simulate pseudo-bulk RNAseq samples from scRNAseq expression data (Software). Version 1.1.1. In: GitHub. (Weblink)

  • Marini, Federico; Finotello, Francesca (2022): quantiseqR: Quantification of the Tumor Immune contexture from RNA-seq data (Software). Version 1.4.0. In: Bioconductor. Open Source Software for Bioinformatics. (DOI) (Weblink)

  • Merotto, Lorenzo; Dietrich, Alexander; Pelz, Konstantin; Reinisch, Katharina; Zackl, Constantin; Marini, Federico; Sturm, Gregor; List, Markus; Finotello, Francesca (2022): omnideconv (Software). Version Beta. In: GitHub. (Weblink)

  • Rieder, Dietmar; Fotakis, Georgios; Ausserhofer, Markus; Geyeregger, René; Paster, Wolfgang; Trajanoski, Zlatko; Finotello, Francesca (2022): nextNEOpi: Nextflow NeoEpitope predictions Pipeline (Software). Version v1.3.2b. In: GitHub. (Weblink)

  • Sturm, Gregor; Finotello, Francesca; Petitprez, Florent; Zhang, Jitao David; Baumbach, Jan; Fridman, Wolf H.; List, Markus; Aneichyk, Tatsiana (2022): immunedeconv. An R package for unified access to computational methods for estimating immune cell fractions from bulk RNA sequencing data (Software). Version v2.1.0. In: GitHub. (Weblink)

  • Sturm, Gregor; Szabo, Tamas; Georgios, Fotakis; Haider, Marlene; Rieder, Dietmar; Trajanoski, Zlatko; Finotello, Francesca (2022): Scirpy: A Scanpy extension for analyzing single-cell immune-cell receptor sequencing data (Software). Version v0.11.1. In: GitHub. (Weblink)

  • Zackl, Constantin; Dietrich, Alexander; Merotto, Lorenzo; Pelz, Konstantin; Eder, Bernhard; Reinisch, Katharina; Marini, Federico; Sturm, Gregor; List, Markus; Finotello, Francesca (2021-2024): deconvExplorer (Software). Version 1. In: GitHub. (Weblink)



Publikationen 2021

(Mit-)Herausgeberschaft von Periodika / Buchreihen

Herausgeberschaft von Periodikum / Buchreihe
  • Finotello, Francesca: Associate Editor - Molecular & Cellular Oncology, 01.01.2021 lfd. (Weblink)

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)
  • Biglari, Nasim; Gaziano, Isabella; Schumacher, Jonas; Radermacher, Jan; Paeger, Lars; Klemm, Paul; Chen, Weiyi; Corneliussen, Svenja; Wunderlich, Claudia M.; Sue, Michael; Vollmar, Stefan; Klöckener, Tim; Sotelo-Hitschfeld, Tamara; Abbasloo, Amin; Edenhofer, Frank; Reimann, Frank; Gribble, Fiona M; Fenselau, Henning; Kloppenburg, Peter; Wunderlich, Frank T; Brüning, Jens C (2021): Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting.
    In: Nature Neuroscience 24/7, S. 913 - 929. (DOI) (Weblink)

  • Casteels, T.; Zhang, Y.; Frogne, T.; Sturtzel, C.; Lardeau, CH; Sen, I.; Liu, X.; Hong, S.; Pauler, FM; Penz, T.; Brandstetter, M.; Barbieux, C.; Berishvili, E.; Heuser, T.; Bock, C.; Riedel, CG; Meyer, D.; Distel, M.; Hecksher-Sørensen, J.; Li, J.; Kubicek, S. (2021): An inhibitor-mediated beta-cell dedifferentiation model reveals distinct roles for FoxO1 in glucagon repression and insulin maturation.
    In: Molecular Metabolism 54, Nr. 101329. (DOI) (Weblink)

  • Esterhuizen, M.; Schmitner, N.; Pflugmacher, S. (2021): Bioavailability of microcystin-LR in two different soil types to the legume Alfalfa Medicago sativa L.
    In: International Journal of Environmental Science and Technology 18/12, S. 3845 - 3854. (DOI) (Weblink)

  • Grill, Nina; Fellner, Lisa; Tisch, Marcel; Edenhofer, Frank (2021): iPS-abgeleitete Kardiomyozyten als therapeutische Hoffnungsträger.
    In: BIOspektrum 27/4, S. 362 - 364. (Volltext) (DOI) (Weblink)

  • Jansch, Charline; Ziegler, Georg C; Forero, Andrea; Gredy, Sina; Wäldchen, Sina; Vitale, Maria Rosaria; Svirin, Evgeniy; Zöller, Johanna E M; Waider, Jonas; Günther, Katharina; Edenhofer, Frank; Sauer, Markus; Wischmeyer, Erhard; Lesch, Klaus-Peter (2021): Serotonin-specific neurons differentiated from human iPSCs form distinct subtypes with synaptic protein assembly.
    In: Journal of Neural Transmission 128/2, S. 225 - 241. (DOI) (Weblink)

  • Janz, Anna; Zink, Miriam; Cirnu, Alexandra; Hartleb, Annika; Albrecht, Christina; Rost, Simone; Klopocki, Eva; Günther, Katharina; Edenhofer, Frank; Ergün, Süleyman; Gerull, Brenda (2021): CRISPR/Cas9-edited PKP2 knock-out (JMUi001-A-2) and DSG2 knock-out (JMUi001-A-3) iPSC lines as an isogenic human model system for arrhythmogenic cardiomyopathy (ACM).
    In: Stem Cell Research 53, No. 102256. (DOI) (Weblink)

  • Liu, Ka-Cheuk; Villasenor, Alethia; Bertuzzi, Maria; Schmitner, Nicole; Radros, Niki; Rautio, Linn; Mattonet, Kenny; Matsuoka, Ryota L.; Reischauer, Sven; Stainier, Didier Y.R.; Andersson, Olov (2021): Insulin-producing β-cells regenerate ectopically from a mesodermal origin under the perturbation of hemato-endothelial specification.
    In: eLife 10, No. e65758. (DOI) (Weblink)

  • Mertens, Jerome; Herdy, Joseph R; Traxler, Larissa; Schafer, Simon T; Schlachetzki, johannes C M; Böhnke, Lena; Reid, Dylan A; Lee, Hyungjun; Zangwill, Dina; Fernandes, Diana; Agarwal, Ravi K; Lucciola, Raffaella; Zhou-Yang, Lucia; Karbacher, Lukas; Edenhofer, Frank; Stern, Shani; Horvath, Steve; Paquola, Apua C M; Glass, Christopher K; Yuan, Shauna H; Ku, Manching; Szücs, Attila; Goldstein, Lawrence S B; Galasko, Douglas; Gage, Fred H (2021): Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer’s patients.
    In: Cell Stem Cell 28/9, S. 1533 - 1548. (DOI) (Weblink)

  • Qu, Z.; Forster, D.; Bruni, E.; Frantal, D.; Kammerlander, B.; Nachbaur, L.; Pitsch, G.; Posch, T.; Pröschold, T.; Teubner, K.; Sonntag, B.; Stoeck, T. (2021): Aquatic food webs in deep temperate lakes: Key species establish through their autecological versatility.
    In: Molecular Ecology 30/4, S. 1053 - 1071. (DOI) (Weblink)

  • Salti, Ahmad; Etemad, Solmaz; Suarez Cubero, Marta; Albertini, Eva; Kovacs-Szalka, Beata; Holzknecht, Max; Cappuccio, Elia; Cavinato, Maria; Edenhofer, Frank; Jansen Dürr, Pidder (2021): High Glycolytic Activity Enhances Stem Cell Reprogramming of Fahd1-KO Mouse Embryonic Fibroblasts.
    In: Cells 10/8, No. 2040. (DOI)

  • Schmitner, Nicole; Recheis, Christina; Thönig, Jakob; Kimmel, Robin A. (2021): Differential Responses of Neural Retina Progenitor Populations to Chronic Hyperglycemia.
    In: Cells 10/11, No. 3265. (DOI) (Weblink)

  • Soni, A; Klutsch, D; Hu, X; Houtman, J; Rund, N; McCloskey, A; Mertens, J; Schafer, ST; Amin, H; Toda, T (2021): Improved Method for Efficient Generation of Functional Neurons from Murine Neural Progenitor Cells.
    In: Cells 10/8, No. 1894. (DOI) (Weblink)

  • Temocin, O.; Regele, D.; Sathianathan, M.; Überbacher, C.; Hartl, M.; Edenhofer, F.; Meyer, D. (2021): Generation of an hiPSC-1 knock-in line expressing TY1-tagged MNX1-protein together with mScarlet.
    In: Stem Cell Research 56, Nr. 102522. (Volltext) (DOI) (Weblink)

  • Tschaikner, P; Regele, D; Röck, R; Salvenmoser, W; Meyer, D; Bouvier, M; Geley, S; Stefan, E; Aanstad, P (2021): Feedback Control of the Gpr161-G αs-PKA axis contributes to basal Hedgehog repression in zebrafish.
    In: Development 148/4, Nr. dev192443. (DOI) (Weblink)

  • Vitale, MR; Zöller, JEM; Jansch, C; Janz, A; Edenhofer, F; Klopocki, E; van den Hove, D; Vanmierlo, T; Rivero, O; Nadif Kasri, N; Ziegler, GC; Lesch, KP (2021): Generation of induced pluripotent stem cell (iPSC) lines carrying a heterozygous (UKWMPi002-A-1) and null mutant knockout (UKWMPi002-A-2) of Cadherin 13 associated with neurodevelopmental disorders using CRISPR/Cas9.
    In: Stem Cell Research 51, Nr. 102169. (DOI) (Weblink)

Zeitschriftenaufsatz (Review)
  • Fellner, Lisa; Gabassi, Elisa; Haybaeck, johannes; Edenhofer, Frank (2021): Autophagy in α-Synucleinopathies-An Overstrained System.
    In: Cells 10/11, No. 3143. (DOI) (Weblink)

  • Traxler, L.; Lagerwall, J.; Eichhorner, S.; Stefanoni, D.; D' Alessandro, A.; Mertens, J. (2021): Metabolism navigates neural cell fate in development, aging and neurodegeneration.
    In: Disease Models and Mechanisms 14/8, Nr. dmm048993. (DOI) (Weblink)

Zeitschriftenbeitrag (Editorial)
  • Herdy, Joseph R.; L Karbacher, Lukas; Mertens, Jerome (2021): One Big Step to a Neuron, Two Small Steps for miRNAs.
    In: Cell Stem Cell 28/1, S. 1 - 2. (DOI) (Weblink)

Sonstige Publikationen

elektronische Publikation, wissenschaftliche
  • Edenhofer, F.; Tisch, Marcel (2021): Von Blutzellen zu Stammzellen: Neue Wege der Zellreprogrammierung (Portal universimed.com). (Weblink)

Forschungsdaten

  • Zackl, Constantin; Dietrich, Alexander; Merotto, Lorenzo; Pelz, Konstantin; Eder, Bernhard; Reinisch, Katharina; Marini, Federico; Sturm, Gregor; List, Markus; Finotello, Francesca (2021-2024): deconvExplorer (Software). Version 1. In: GitHub. (Weblink)



Publikationen 2020

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)
  • Ali, Zaheer; Zang, Jingjing; Lagali, Neil; Schmitner, Nicole; Salvenmoser, Willi; Mukwaya, Anthony; Neuhauss, SCF; Jensen, Lasse D.; Kimmel, Robin A. (2020): Photoreceptor degeneration accompanies vascular changes in a zebrafish model of diabetic retinopathy.
    In: Investigative Ophthalmology & Visual Science 61/2, No. 43. (DOI) (Weblink)

  • Braga, A.; Bandiera, S.; Verheyen, J.; Hamel, R.; Rutigliani, C.; Edenhofer, Frank; Smith, J.A.; Pluchino, S. (2020): Combination of In Situ Lcn2 pRNA-RNAi Nanotherapeutics and iNSC Transplantation Ameliorates Experimental SCI in Mice.
    In: Molecular Therapy 28/12, S. 2677 - 2690. (DOI) (Weblink)

  • Freudenblum, Julia; Meyer, Dirk; Kimmel, Robin A. (2020): Inducible Mosaic Cell Labeling Provides Insights Into Pancreatic Islet Morphogenesis.
    In: Frontiers in Cell and Developmental Biology 8, No. 586651. (DOI) (Weblink)

  • Ginno, Paul Adrian; Gaidatzis, Dimos; Feldmann, Angelika; Hoerner, Leslie; Imanci, Dilek; Burger, Lukas; Zilbermann, Frederic; Peters, Antoine H. F. M.; Edenhofer, Frank; Smallwood, Sebastien A.; Krebs, Arnaud R.; Schuebeler, Dirk (2020): A genome-scale map of DNA methylation turnover identifies site-specific dependencies of DNMT and TET activity.
    In: Nature Communications 11/1, No. 2680. (DOI) (Weblink)

  • Gollmann-Tepeköylü, Can; Nägele, Felix; Graber, Michael; Pölz, Leo; Lobenwein, Daniela; Hirsch, Jakob; An, Angela; Irschick, Regina; Röhrs, Bernhard; Kremser, Christian; Hackl, Hubert; Huber, Rosalie; Venezia, Serena; Hercher, David; Fritsch, Helga; Bonaros, Nikolaos; Stefanova, Nadia; Tancevski, Ivan; Meyer, Dirk; Grimm, Michael; Holfeld, johannes (2020): Shock waves promote spinal cord repair via TLR3.
    In: JCI Insight 5/15, No. e134552. (DOI) (Weblink)

  • Janz, A; Chen, RP; Regensburger, M; Ueda, Y; Rost, S; Klopocki, E; Gunther, K; Edenhofer, F; Du, HJ; Ergun, S; Gerull, B (2020): Generation of two patient-derived iPSC lines from siblings (LIBUCi001-A and LIBUCi002-A) and a genetically modified iPSC line (JMUi001-A-1) to mimic dilated cardiomyopathy with ataxia (DCMA) caused by a homozygous DNAJC19 mutation.
    In: Stem Cell Research 46, No. 101856. (DOI) (Weblink)

  • Krziminski, C; Kammann, S; Hansmann, J; Edenhofer, F; Dandekar, G; Walles, H; Leistner, M (2020): Development of a bioreactor system for pre-endothelialized cardiac patch generation with enhanced viscoelastic properties by combined collagen I compression and stromal cell culture.
    In: Journal of Tissue Engineering and Regenerative Medicine  14/12, S. 1749 - 1762. (DOI) (Weblink)

  • Palladino, VS; Chiocchetti, AG; Frank, L; Haslinger, D; McNeill, R; Radtke, F; Till, A; Haupt, S; Brustle, O; Gunther, K; Edenhofer, F; Hoffmann, P; Reif, A; Kittel-Schneider, S (2020): Energy Metabolism Disturbances in Cell Models of PARK2 CNV Carriers with ADHD.
    In: Journal of Clinical Medicine 9/12, No. 4092. (DOI) (Weblink)

  • Sullivan, Genevieve M.; Knutsen, Andrew K.; Peruzzotti-Jametti, Luca; Korotcov, Alexandru; Bosomtwi, Asamoah; Dardzinski, Bernard J.; Bernstock, Joshua D.; Rizzi, Sandra; Edenhofer, Frank; Pluchino, Stefano; Armstrong, Regina C. (2020): Transplantation of induced neural stem cells (iNSCs) into chronically demyelinated corpus callosum ameliorates motor deficits.
    In: Acta Neuropathologica Communications 8, No. 84. (DOI) (Weblink)

Zeitschriftenaufsatz (Review)
  • Schlachetzki, johannes CM; Toda, Tomohisa; Mertens, Jerome (2020): When function follows form: Nuclear compartment structure and the epigenetic landscape of the aging Neuron.
    In: Experimental Gerontology 133, No. 110876. (DOI) (Weblink)

  • Tschaikner, Philipp; Enzler, Florian; Torres-Quesada, Omar; Aanstad, Pia; Stefan, Eduard (2020): Hedgehog and Gpr161: Regulating cAMP Signaling in the Primary Cilium.
    In: Cells 9/1, No. E118. (DOI) (Weblink)



Publikationen 2019

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)
  • Emfinger, Christopher H.; Lőrincz, Réka; Wang, Yixi; York, Nathaniel W.; Singareddy, Soma S.; Ikle, Jennifer M.; Tryon, Robert C.; McClenaghan, Conor; Shyr, Zeenat A.; Huang, Yan; Reissaus, Christopher A.; Meyer, Dirk; Piston, David W.; Hyrc, Krzysztof; Remedi, Maria S.; Nichols, Colin G. (2019): Beta‐cell excitability and excitability‐driven diabetes in adult Zebrafish islets.
    In: Physiological Reports 7/11, S. e14101. (DOI) (Weblink)

  • Fischer, Patrick; Chen, Hao; Pacho, Frederic; Rieder, Dietmar; Kimmel, Robin A.; Meyer, Dirk (2019): FoxH1 represses miR-430 during early embryonic development of zebrafish via non-canonical regulation.
    In: BMC Biology 17/1, No. 61. (DOI) (Weblink)

  • Herdy, J.; Schafer, S.; Kim, Y.; Ansari, Z.; Zangwill, D.; Ku, M.; Paquola, A.; Lee, H.; Mertens, J.; Gage, FH. (2019): Chemical modulation of transcriptionally enriched signaling pathways to optimize the conversion of fibroblasts into neurons.
    In: eLife 17/8, S. e41356. (DOI) (Weblink)

  • Klein, T.; Klug, K.; Henkel, L.; Kwok, CK; Edenhofer, F.; Klopocki, E.; Kurth, I.; Üçeyler, N. (2019): Generation of two induced pluripotent stem cell lines from skin fibroblasts of sisters carrying a c.1094C>A variation in the SCN10A gene potentially associated with small fiber neuropathy.
    In: Stem Cell Research 35, No. 101396. (DOI) (Weblink)

  • Miggitsch, Carina; Meryk, Andreas; Naismith, Erin; Pangrazzi, Luca; Ejaz, Asim; Jenewein, Brigitte; Wagner, Sonja; Nägele, Fabiana; Fenkart, Gabriella; Trieb, Klemens; Zwerschke, Werner; Grubeck-Loebenstein, Beatrix. (2019): Human bone marrow adipocytes display distinct immune regulatory properties.
    In: EBioMedicine 46, S. 387 - 398. (DOI) (Weblink)

  • Schafer, ST; Paquola, ACM; Stern, S; Gosselin, D.; Ku, M.; Pena, M.; Kuret, TJM; Liyanage, M.; Mansour, AA; Jaeger, BN; Marchetto, MC; Glass, CK; Mertens, J; Gage, FH. (2019): Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons.
    In: Nature Neuroscience 22/2, S. 243 - 255. (DOI) (Weblink)

  • Sturm, Gregor; Finotello, Francesca; Petitprez, Florent; Zhang, Jitao David; Baumbach, Jan; Fridman, Wolf H; List, Markus; Aneichyk, Tatsiana (2019): Comprehensive evaluation of transcriptome-based cell-type quantification methods for immuno-oncology.
    In: Bioinformatics 35/14, S. i436 - i445. (DOI) (Weblink)

  • Thier, MC; Hommerding, O.; Panten, J.; Pinna, R.; García-González, D.; Berger, T.; Wörsdörfer, P.; Assenov, Y.; Scognamiglio, R.; Przybylla, A..; Kaschutnig, P.; Becker, L.; Milsom, MD; Jauch, A.; Utikal, J.; Herrmann, C.; Monyer, H.; Edenhofer, F.; Trumpp, A.. (2019): Identification of Embryonic Neural Plate Border Stem Cells and Their Generation by Direct Reprogramming from Adult Human Blood Cells.
    In: Cell Stem Cell 24/1, S. 166 - 182. (DOI) (Weblink)

Zeitschriftenaufsatz (Review)
  • Erharter, A.; Rizzi, S.; Mertens, J.; Edenhofer, F. (2019): Take the shortcut: Direct conversion of somatic cells into induced neural stem cells and their biomedical applications.
    In: FEBS Letters 593/23, S. 3353 - 3369. (DOI) (Weblink)

  • Traxler, L.; Edenhofer, F.; Mertens, J. (2019): Next-generation disease modeling with direct conversion: A new path to old Neurons.
    In: FEBS Letters 593/23, S. 3316 - 3337. (DOI) (Weblink)

Zeitschriftenbeitrag (Meeting-Abstract)
  • Peruzzotti-Jametti, L; Vicario, N; Rizzi, S; Braga, A; Volpe, G; Kwok, CK; Bergholt, M; D'Amico, G; Stevens, M; Zhao, C; Edenhofer, F; Franklin, R; Pluchino, S (2019): Transplantation of directly induced Neural Stem Cell (iNSCs) promotes remyelination in a mouse model of experimental focal demyelination.
    In: GLIA 67, S. E497.

Medienbeiträge

Beitrag in Publikumszeitschrift
  • Edenhofer, Frank: Interview zum Thema: "Jungbrunnen Gefäße".
    In: top.Tirol vom 01.09.2019. (Weblink)

Beitrag in Zeitung
  • Edenhofer, Frank: 10 Dinge, die 2018 gut liefen: 10. Forscher züchteten erstmals Stammzellen aus Blut.
    In: profil online vom 03.01.2019. (Weblink)

Beitrag in (Web-)Radiosendung
  • Edenhofer, Frank: Stammzellen als Hoffnungsträger zur Heilung von Alzheimer.
    In: ORF Radio Tirol - Mittagsinformation vom 17.10.2019.



Publikationen 2018

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)
  • Eftekharzadeh, Bahareh; Daigle, J. Gavin; Kapinos, Larisa E.; Coyne, Alyssa; Schiantarelli, Julia; Carlomagno, Yari; Cook, Casey; Miller, Sean J.; Dujardin, Simon; Amaral, Ana S.; Grima, Jonathan C.; Bennett, Rachel E.; Tepper, Katharina; DeTure, Michael; Vanderburgh, Charles R.; Corjuc, Bianca T.; DeVos, Sarah L.; Gonzalez, Jose Antonio; Chew, Jeannie; Vidensky, Svetlana; Gage, Fred H.; Mertens, Jerome; Troncoso, Juan; Mandelkow, Eckhard; Salvatella, Xavier; Lim, Roderick Y. H.; Petrucelli, Leonard; Wegmann, Susanne; Rothstein, Jeffrey D.; Hyman, Bradley T. (2018): Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease.
    In: Neuron 99/5, S. 925 - 940. (DOI) (Weblink)

  • Freudenblum, J.; Iglesias, JA; Hermann, M.; Walsen, T.; Wilfinger, A.; Meyer, D.; Kimmel, RA. (2018): In vivo imaging of emerging endocrine cells reveals a requirement for PI3K¬regulated motility in pancreatic islet morphogenesis.
    In: Development 145/3, Article dev158477. (DOI) (Weblink)

  • Jansch, C.; Günther, K.; Waider, J.; Ziegler, GC; Forero, A; Kollert, S; Svirin, E.; Pühringer, D.; Kwok, CK; Ullman, R.; Maierhofer, A.; Flunkert, J.; Haaf, T.; Edenhofer, F.; Lesch, KP. (2018): Generation of a human induced pluripotent stem cell (iPSC) line from a 51-year-old female with attention-deficit/hyperactivity disorder (ADHD) carrying a duplication of SLC2A3.
    In: Stem Cell Research 28, S. 136 - 140. (DOI)

  • Jovanovic, VM; Salti, A; Tilleman, H; Zega, K; Jukic, MM; Zou, H; Friedel, RH; Prakash, N; Blaess, S; Edenhofer, F; Brodski, C. (2018): BMP/SMAD Pathway Promotes Neurogenesis of Midbrain Dopaminergic Neurons In Vivo and in Human Induced Pluripotent and Neural Stem Cells.
    In: The Journal of Neuroscience 38/7, S. 1662 - 1676. (DOI) (Weblink)

  • Kim, Y.; Zheng, X; Ansari, Z.; Bunnell, MC; Herdy, JR; Traxler, L.; Lee, H.; Paquola, ACM; Blithikioti, C.; Ku, M.; Schlachetzki, JCM; Winkler, J.; Edenhofer, F.; Glass, CK; Paucar, AA; Jaeger, BN; Pham, S.; Boyer, L.; Campbell, BC; Hunter, T; Mertens, J.; Gage, FH. (2018): Mitochondrial Aging Defects Emerge in Directly Reprogrammed Human Neurons due to Their Metabolic Profile.
    In: Cell Reports 23/9, S. 2550 - 2558. (DOI) (Weblink)

  • Klein, T.; Günther, K.; Kwok, CK; Edenhofer, F.; Üçeyler, N. (2018): Generation of the human induced pluripotent stem cell line (UKWNLi001-A) from skin fibroblasts of a woman with Fabry disease carrying the X-chromosomal heterozygous c.708 G > C (W236C) missense mutation in exon 5 of the alpha-galactosidase-A gene.
    In: Stem Cell Research 31, S. 222 - 226. (DOI) (Weblink)

  • Kwok, CK; Ueda, Y; Kadari, A; Günther, K; Ergün, S; Heron, A; Schnitzler, AC; Rook, M; Edenhofer, F. (2018): Scalable stirred suspension culture for the generation of billions of human induced pluripotent stem cells using single‐use bioreactors.
    In: Journal of Tissue Engineering and Regenerative Medicine  12/2, S. e1076 - e1087. (DOI) (Weblink)

  • Lorincz, R.; Emfinger, CH; Walcher, A; Giolai, M; Krautgasser, C.; Remedi, MS.; Nichols, CG.; Meyer, D. (2018): In vivo monitoring of intracellular Ca2+ dynamics in the pancreatic β-cells of zebrafish embryos.
    In: Islets 10/6, S. 221 - 238. (Volltext) (DOI) (Weblink)

  • Mekala, SR; Wörsdörfer, P; Bauer, J.; Stoll, O.; Wagner, N.; Reeh, L.; Loew, K.; Eckner, G.; Kwok, CK; Wischmeyer, E.; Dickinson, ME; Schulze, H.; Stegner, D.; Benndorf, RA.; Edenhofer, F.; Pfeiffer, V.; Kuerten, S.; Frantz, S.; Ergün S. (2018): Generation of Cardiomyocytes From Vascular Adventitia-Resident Stem Cells.
    In: CIRCULATION RESEARCH 123/6, S. 686 - 699. (DOI) (Weblink)

  • Nose, N.; Werner, RA; Ueda, Y.; Günther, K.; Lapa, C.; Javadi, MS; Fukushima, K.; Edenhofer, F.; Higuchi, T. (2018): Metabolic substrate shift in human induced pluripotent stem cells during cardiac differentiation: Functional assessment using in vitro radionuclide uptake assay.
    In: International Journal of Cardiology 269, S. 229 - 234. (DOI) (Weblink)

  • Peruzzotti-Jametti, L.; Bernstock, JD; Vicario, N; Costa, ASH; Kwok, CK; Leonardi, T.; Booty, LM; Bicci, I.; Balzarotti, B.; Volpe, G.; Mallucci, G.; Manferrari, G.; Donegà, M.; Iraci, N.; Braga, A.; Hallenbeck, JM; Murphy, MP; Edenhofer, F; Frezza, C.; Pluchino, S. (2018): Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation.
    In: Cell Stem Cell 22/3, S. 355 - 368. (DOI) (Weblink)

  • Popp, B.; Krumbiegel, M.; Grosch, J.; Sommer, A..; Uebe, S.; Kohl, Z.; Plötz, S.; Farrell, M.; Trautmann, U.; Kraus, C.; Ekici, AB; Asadollahi, R.; Regensburger, M.; Günther, K.; Rauch, A.; Edenhofer, F.; Winkler, J.; Winner, B.; Reis, A. (2018): Need for high-resolution Genetic Analysis in iPSC: Results and Lessons from the ForIPS Consortium.
    In: Scientific Reports 8/1, S. 17201. (DOI) (Weblink)

  • Salti, A; Apostolova, G; Kummer, KK; Lemos, C; Dechant, G; El Rawas, R (2018): Cocaine Paired Environment Increases SATB2 Levels in the Rat Paraventricular Thalamus.
    In: Frontiers In Behavioral Neuroscience 12, No. 224. (DOI)

Zeitschriftenaufsatz (Review)
  • Mertens, Jerome; Reid, Dylan; Lau, Shong; Kim, Yongsung; Gage, Fred H (2018): Aging in a Dish: iPSC-Derived and Directly Induced Neurons for Studying Brain Aging and Age-Related Neurodegenerative Diseases.
    In: ANNUAL REVIEW OF GENETICS 52, S. 271 - 293. (DOI) (Weblink)

Zeitschriftenbeitrag (anderer)
  • Dobeš, Jan; Edenhofer, Frank; Vobořil, Matouš; Brabec, Tomáš; Dobešová, Martina; Čepková, Adéla; Klein, Ludger; Rajewsky, Klaus; Filipp, Dominik (2018): A novel conditional Aire allele enables cell-specific ablation of the immune tolerance regulator Aire.
    In: European Journal of Immunology 48/3, S. 546 - 548. (DOI) (Weblink)

Zeitschriftenbeitrag (Meeting-Abstract)
  • Curinha, A; Klee, K; Shivalingaiah, G; Aanstad, P; Polacek, N; Geley, S (2018): Functional analysis of Rbm26.
    In: Molecular Biology of the Cell 29/26, S. 200.

Medienbeiträge

Beitrag in Zeitung
  • Edenhofer, Frank: Forscher züchteten erstmals Gehirnstammzellen aus Blutzellen.
    In: derStandard.at vom 21.12.2018. (Weblink)

  • Edenhofer, Frank: Tiroler züchten aus Blut Stammzellen.
    In: orf.at vom 21.12.2018.

  • Edenhofer, Frank: Forschung und Vernetzung Tiroler Wissenschaftler.
    In: meinbezirk.at vom 05.12.2018. (Weblink)

  • Edenhofer, Frank: Tiroler Forscher empört über Gen-Versuch an Babys.
    In: Kronen Zeitung vom 05.12.2018. (Weblink)

  • Edenhofer, Frank: Tirols Mediziner vereinen sich.
    In: Tiroler Tageszeitung vom 05.12.2018. (Weblink)

  • Edenhofer, Frank: Zusammenarbeit soll Forschung anheizen.
    In: orf.at vom 04.12.2018. (Weblink)

  • Edenhofer, Frank: Molekularer Jungbrunnen.
    In: Kronen Zeitung vom 06.11.2018. (Weblink)

  • Edenhofer, Frank: Lebensbausteine.
    In: Newsroom - www.uibk.ac.at vom 01.11.2018. (Weblink)

  • Edenhofer, Frank: Offener Brief zur Unterstützung des FWF.
    In: pressetext.com vom 31.08.2018. (Weblink)

  • Edenhofer, Frank: Für sein großes Gehirn zahlt der Mensch einen hohen Preis.
    In: Focus Online vom 02.06.2018. (Weblink)

  • Edenhofer, Frank: Interview für Artikel "Warum das menschliche Gehirn so groß ist".
    In: science.orf.at vom 01.06.2018. (Weblink)

  • Edenhofer, Frank: Interview für Artikel "Das Gen, das uns das große Gehirn gab".
    In: Die Zeit vom 31.05.2018. (Weblink)

  • Edenhofer, Frank: Interview für Artikel: "Mensch, warum hast du so ein großes Hirn?
    In: Spiegel Online vom 31.05.2018. (Weblink)

  • Edenhofer, Frank: Gründung der Österreichischen Gesellschaft für Stammzellforschung.
    In: Austria Presse Agentur (APA) vom 20.03.2018. (Weblink)

  • Edenhofer, Frank: Stammzellen als Hoffnungsträger der Medizin.
    In: derStandard.at vom 05.03.2018. (Weblink)

  • Edenhofer, Frank: Revolution in der Biomedizin (Interview).
    In: Standort. Nachrichten aus dem Innovations- und Technologieland Tirol vom 01.03.2018. (Weblink)

  • Edenhofer, Frank: Stammzellenforschung: Großes Potenzial, ausbaufähige Fördersituation.
    In: derStandard.at vom 23.02.2018. (Weblink)

  • Edenhofer, Frank: Stammzellforschung steht vor Revolution.
    In: Wiener Zeitung vom 23.02.2018. (Weblink)

Beitrag in (Web-)Radiosendung
  • Edenhofer, Frank: Wichtige Erfolge der Stammzellforschung.
    In: ORF Radio - Ö1 vom 26.04.2018. (Weblink)

  • Edenhofer, Frank: Interview zu Langer Nacht der Forschung.
    In: Radio Freirad - Verein Freies Radio Innsbruck vom 18.04.2018.

  • Edenhofer, Frank:: Durchbruch in der Stammzellforschung.
    In: Radio U1 Tirol vom 21.12.2018.



Publikationen 2017

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)
  • Appelt-Menzel, A.; Cucukova, A.; Günther, K.; Edenhofer, F.; Piontek, J.; Krause, G.; Stüber, T.; Walles, H.; Neuhaus, W.; Metzger, M. (2017): Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells.
    In: STEM CELL REPORTS 8/4, S. 894 - 906. (DOI) (Weblink)

  • Bayer, Fabienne E.; Zimmermann, Mirjam; Fischer, Patrick; Gromoll, Christian; Preiss, Anette; Nagel, Anja C. (2017): p53 and cyclin G cooperate in mediating genome stability in somatic cells of Drosophila.
    In: Scientific Reports 7, No. 17890. (DOI) (Weblink)

  • Facchinello, Nikola; Tarifeño-Saldivia, Estefania; Grisan, Enrico; Schiavone, Marco; Peron, Margherita; Mongera, Alessandro; Ek, Olivier; Schmitner, Nicole; Meyer, Dirk; Peers, Bernard; Tiso, Natascia; Argenton, Francesco (2017): Tcf7l2 plays pleiotropic roles in the control of glucose homeostasis, pancreas morphology, vascularization and regeneration.
    In: Scientific Reports 7/1, No. 9605. (DOI) (Weblink)

  • Filipek, Przemyslaw A.; de Araujo, Mariana E. G.; Vogel, Georg F.; De Smet, Cedric H.; Eberharter, Daniela; Rebsamen, Manuele; Rudashevskaya, Elena L.; Kremser, Leopold; Yordanov, Teodor; Tschaikner, Philipp; Fuernrohr, Barbara G.; Lechner, Stefan; Dunzendorfer-Matt, Theresia; Scheffzek, Klaus; Bennett, Keiryn L.; Superti-Furga, Giulio; Lindner, Herbert H.; Stasyk, Taras; Huber, Lukas A. (2017): D LAMTOR/Ragulator is a negative regulator of Arl8b-and BORC-dependent late endosomal positioning.
    In: The Journal of Cell Biology 216/12, S. 4199 - 4215. (DOI)

  • Forero, A; Rivero, O; Wäldchen, S; Ku, HP; Kiser, DP; Gärtner, Y; Pennington, LS; Waider, J; Gaspar, P; Jansch, C; Edenhofer, F; Resink, TJ; Blum, R; Sauer, M; Lesch, KP. (2017): Cadherin-13 Deficiency Increases Dorsal Raphe 5-HT Neuron Density and Prefrontal Cortex Innervation in the Mouse Brain.
    In: Frontiers in Cellular Neuroscience 11, Article 307. (DOI) (Weblink)

  • Li, J; Casteels, T; Frogne, T; Ingvorsen, C; Honoré, C; Courtney, M; Huber, KV; Schmitner, N; Kimmel, RA; Romanov, RA; Sturtzel, C; Lardeau, CH; Klughammer, J; Farlik, M; Sdelci, S; Vieira, A; Avolio, F; Briand, F; Baburin, I; Májek, P; Pauler, FM; Penz, T; Stukalov, A; Gridling, M; Parapatics, K; Barbieux, C; Berishvili, E; Spittler, A; Colinge, J; Bennett, KL; Hering, S; Sulpice, T; Bock, C; Distel, M; Harkany, T; Meyer, D; Superti-Furga, G; Collombat, P; Hecksher-Sørensen, J; Kubicek, S. (2017): Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity.
    In: Cell 168/1-2, S. 86 - 100. (DOI) (Weblink)

  • Lizen, B; Moens, C; Mouheiche, J; Sacre, T; Ahn, MT; Jeannotte, L; Salti, A; Gofflot, F (2017): Conditional Loss of Hoxa5 Function Early after Birth Impacts on Expression of Genes with Synaptic Function.
    In: Frontiers in Molecular Neuroscience 10, No. 369. (DOI)

  • Schmitner, Nicole; Kohno, Kenji; Meyer, Dirk (2017): Ptf1a+, ela3l− cells are developmentally maintained progenitors for exocrine regeneration following extreme loss of acinar cells in zebrafish larvae.
    In: Disease Models and Mechanisms 10, S. 307 - 321. (DOI) (Weblink)

  • Wörsdörfer, Philipp; Bosen, Felicitas; Gebhardt, Martina; Russ, Nicole; Zimmermann, Katrin; Komla Kessie, David; Sekaran, Thileepan; Egert, Angela; Ergün, Süleyman; Schorle, Hubert; Pfeifer, Alexander; Edenhofer, Frank; Willecke, Klaus (2017): Abrogation of Gap Junctional Communication in ES Cells Results in a Disruption of Primitive Endoderm Formation in Embryoid Bodies.
    In: STEM CELLS 35/4, S. 859 - 871. (DOI) (Weblink)

  • Wörsdörfer, Philipp; Mekala, SR; Bauer, J.; Edenhofer, F; Kuerten, S.; Ergün, S. (2017): The vascular adventitia: An endogenous, omnipresent source of stem cells in the body.
    In: Pharmacology & Therapeutics 171, S. 13 - 29. (DOI) (Weblink)

Zeitschriftenbeitrag (Meeting-Abstract)
  • Braga, A; Verheyen, J; Smith, J; Bandiera, S; Edenhofer, F; Pluchino, S (2017): Transplantation of directly induced neural stem cells (iNSCs) in mice with experimental contusion spinal cord injury.
    In: GLIA 65/Supplement 1, No. T13-006C. (DOI) (Weblink)

  • Jensen, Lasse D. E.; Ali, Zaheer; Lagali, Neil S.; Kimmel, Robin A. (2017): Pdx1-mutant zebrafish develop proliferative diabetic retinopathy.
    In: Investigative Ophthalmology & Visual Science 58/8, No. 2510. (Weblink)

  • Peruzzotti-Jametti, L; Bernstock, J; Vicario, N; Costa, ASH; Kwok, CK; Leonardi, T; Booty, L; Bicci, I; Balzarotti, B; Volpe, G; Mallucci, G; Manferrari, G; Iraci, N; Hallenbeck, JM; Murphy, MP; Edenhofer, F; Frezza, C; Pluchino, S (2017): Transplanted induced neural stem cells ameliorate experimental autoimmune encephalomyelitis by metabolic reprogramming of mononuclear phagocytes.
    In: GLIA 65/Supplement 1, No. T13-005C. (DOI) (Weblink)

  • Verheyen, J; Smith, J; Braga, A; Peruzzotti-Jametti, L; Rizzi, S; Edenhofer, F; Pluchino, S (2017): Novel in vitro method for modelling resting and activated astrocytes.
    In: GLIA 65/Supplement 1, No. T14-134A. (DOI) (Weblink)

  • Vicario, N; Peruzzotti-Jametti, L; Braga, A; Rizzi, S; Volpe, G; Balzarotti, B; Manferrari, G; Zhao, C; Edenhofer, F; Franklin, RJM; Pluchino, S (2017): Transplantation of directly induced neural stem cell (iNSCs) promotes remyelination in a mouse model of experimental focal demyelination.
    In: GLIA 65/Supplement 1, No. T13-003C. (DOI) (Weblink)

Lehrbuchbeitrag, wissenschaftlicher
  • Terstegge, S.; Edenhofer, F.; Brüstle, O. (2017): 5.14. Stammzellen - Bedeutung für die klinische Medizin.
    In: Murken, J.; Grimm, T.; Holinski-Feder, E.; Zerres, K.: Taschenlehrbuch Humangenetik. Stuttgart: Georg Thieme Verlag., ISBN 978-3-13-241687-1, 9., teilak. Auflage, S. 567 - 573. (DOI) (Weblink)

Medienbeiträge

Beitrag in Publikumszeitschrift
  • Röck, Susanne; Jansen-Dürr, Pidder; Edenhofer, Frank: Die Geheimnisse des Alterns.
    In: wissenswert - Magazin der Universität Innsbruck vom 11.04.2017. (Weblink)

Beitrag in Zeitung
  • Edenhofer, Frank: Interview zu "Auf der Suche nach dem Jungbrunnen".
    In: Tiroler Tageszeitung online vom 28.11.2017.

  • Edenhofer, Frank: Hautzellen zu Hirnzellen umprogrammieren.
    In: Spektrum.de vom 23.11.2017.

  • Edenhofer, Frank: Neuronen-Transplantation lindert Parkinson-Degeneration bei Affen, Interview.
    In: Der Standard vom 31.08.2017. (Weblink)

  • Edenhofer, Frank: Forscher testen an Affen erfolgreich neue Therapie gegen Parkinson, Interview.
    In: Süddeutsche Zeitung vom 30.08.2017. (Weblink)

  • Edenhofer, Frank: Hoffnung auf neue Therapie bei Parkinson, Interview.
    In: Die Welt vom 30.08.2017. (Weblink)

  • Edenhofer, Frank: Interview zu "Stem cell hope for treating Parkinson's".
    In: The Times vom 30.08.2017.

  • Edenhofer, Frank: Forschungssensation: Erstmals Blutstammzellen im Labor gezüchtet.
    In: Focus Online vom 18.05.2017. (Weblink)

  • Edenhofer, Frank: Interview zum Thema: Forscher züchten erstmals menschliche Blutstammzellen.
    In: Spiegel Online vom 18.05.2017. (Weblink)

Beitrag in (Web-)Radiosendung
  • Edenhofer, Frank: Stammzellforschung in Innsbruck. Wissenschaftler machen aus Hautzellen Gehirnzellen und wollen Krankheiten besser verstehen.
    In: Tirol TV vom 23.10.2017. (Weblink)



Publikationen 2016

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)
  • Bachmann, Verena A.; Mayrhofer, Johanna E.; Ilouz, Ronit; Tschaikner, Philipp; Raffeiner, Philipp; Röck, Ruth; Courcelles, Mathieu; Apelt, Federico; Lu, Tsan-Wen; Baillie, George S.; Thibault, Pierre; Aanstad, Pia; Stelzl, Ulrich; Taylor, Susan S.; Stefan, Eduard (2016): Gpr161 anchoring of PKA consolidates GPCR and cAMP signaling.
    In: PNAS. Proceedings of the National Academy of Sciences 113/28, S. 7786 - 7791. (DOI) (Weblink)

  • Bung, Raffaela; Wörsdörfer, Philipp; Thier, Marc Christian; Vogt, Kathrin; Gebhardt, Martina; Edenhofer, Frank (2016): Partial dedifferentiation of murine radial glia type neural stem cells by Brn2 and c-Myc yields early neuroepithelial progenitors.
    In: Journal of Molecular Biology 428/7, S. 1476 - 1483. (DOI) (Weblink)

  • Fischer, Patrick; Preiss, Anette; Nagel, Anja C. (2016): A triangular connection between Cyclin G, PP2A and Akt1 in the regulation of growth and metabolism in Drosophila.
    In: Fly 10/1, S. 11 - 18. (DOI)

  • Kimmel, R. A.; Meyer, D. (2016): Chapter 13 – Zebrafish pancreas as a model for development and disease.
    In: METHODS IN CELL BIOLOGY 134, S. 431 - 461. (DOI)

  • Kruszewski, K; Lüllmann-Rauch, R.; Dierks, T.; Bartsch, U; Damme, M. (2016): Degeneration of Photoreceptor Cells in Arylsulfatase G-Deficient Mice.
    In: Investigative Ophthalmology & Visual Science 57/3, S. 1120 - 1131. (DOI) (Weblink)

  • Münst, B; Thier, M; Winnemöller, D; Helfen, M; Thummer, RP; Edenhofer, F (2016): Nanog induces suppression of senescence via downregulation of p27KIP1 expression.
    In: JOURNAL OF CELL SCIENCE 129/5, S. 912 - 920. (DOI)

  • Ott, Elisabeth; Wendik, Björn; Srivastava, Monika; Pacho, Frederic; Töchterle, Sonja; Salvenmoser, Willibald; Meyer, Dirk (2016): Pronephric tubule morphogenesis in zebrafish depends on Mnx mediated repression of irx1b within the intermediate mesoderm.
    In: Developmental Biology 411/1, S. 101 - 114. (DOI) (Weblink)

  • Rizzi, S.; Knaus, HG; Schwarzer, C. (2016): Differential distribution of the sodium-activated potassium channels slick and slack in mouse brain.
    In: JOURNAL OF COMPARATIVE NEUROLOGY 524/10, S. 2093 - 2116. (DOI) (Weblink)

  • Safina, D; Schlittk, F; Romeo, R; Pflanzner, T; Pietrzik, CU; Narayanaswami, V; Edenhofer, F.; Faissner, A (2016): Low-density lipoprotein receptor-related protein 1 is a novel modulator of radial glia stem cell proliferation, survival, and differentiation.
    In: GLIA 64/8, S. 1363 - 1380. (DOI)

  • Schulze, M; Hoja, S; Winner, B; Winkler, J; Edenhofer, F; Riemenschneider MJ (2016): Model Testing of PluriTest with Next-Generation Sequencing Data.
    In: STEM CELLS AND DEVELOPMENT 25/7, S. 569 - 571. (DOI) (Weblink)

  • Scognamiglio, R; Cabezas-Wallscheid, N; Thier, MC; Altamura, S; Reyes, A; Prendergast, ÁM; Baumgärtner, D; Carnevalli, LS; Atzberger, A; Haas, S; von Paleske, L; Boroviak, T; Wörsdörfer, P; Essers, MA; Kloz, U; Eisenman, RN; Edenhofer, F; Bertone, P; Huber, W; van der Hoeven, F; Smith, A; Trumpp, A. (2016): Myc Depletion Induces a Pluripotent Dormant State Mimicking Diapause.
    In: Cell 164/4, S. 668 - 680. (DOI) (Weblink)

Medienbeiträge

Beitrag in Publikumszeitschrift
  • Edenhofer, Frank: Aus Haut mach Hirn.
    In: wissenswert - Magazin der Universität Innsbruck vom 11.10.2016. (Weblink)

Beitrag in Zeitung
  • Edenhofer, Frank: Wenn Hirn aus der Haut fährt (Interview).
    In: Tiroler Tageszeitung vom 24.06.2016. (Weblink)

  • Edenhofer, Frank: Vorgestellt: Der Zell­program­mierer (Interview).
    In: Newsroom - www.uibk.ac.at vom 15.03.2016. (Weblink)

Beitrag in (Web-)Radiosendung
  • Edenhofer, Frank: ZfW_031 - Stammzellen.
    In: Zeit für Wissenschaft - Der Wissenschaftspodcast (Universität Innsbruck) vom 23.06.2016. (Weblink)



Publikationen 2015

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)
  • Astone, M.; Pizzi, M.; Peron, M.; Domenichini, A.; Guzzardo, V.; Töchterle, S.; Tiso, N.; Rugge, M.; Meyer, D.; Argenton, F.; Vettori, A. (2015): A GFP-Tagged Gross Deletion on Chromosome 1 Causes Malignant Peripheral Nerve Sheath Tumors and Carcinomas in Zebrafish.
    In: PLoS One 10/12, S. e0145178. (DOI) (Weblink)

  • Chen, H.; Babino, D; Schoenbichler, SA.; Arkhipova, V; Töchterle, S; Martin, F; Huck, CW; von Lintig, J; Meyer, D (2015): Nmnat1-Rbp7 Is a Conserved Fusion-Protein That Combines NAD+ Catalysis of Nmnat1 with Subcellular Localization of Rbp7.
    In: PLoS One 10/11, S. e0143825. (DOI) (Weblink)

  • Fischer, Patrick; La Rosa, Martina K.; Schulz, Adriana; Preiss, Anette; Nagel, Anja C. (2015): Cyclin G Functions as a Positive Regulator of Growth and Metabolism in Drosophila.
    In: PLoS Genetics 11/8, Article e1005440. (DOI) (Weblink)

  • Kimmel, Robin A.; Dobler, Stefan; Schmitner, Nicole; Walsen, Tanja; Freudenblum, Julia; Meyer, Dirk (2015): Diabetic pdx1-mutant zebrafish show conserved responses to nutrient overload and anti-glycemic treatment.
    In: Scientific Reports 5, Art. Nr. 14241. (DOI) (Weblink)

  • Röck, R; Bachmann, V; Bhang, HC; Malleshaiah, M; Raffeiner, P; Mayrhofer, JE; Tschaikner, PM; Bister, K; Aanstad, P; Pomper, MG; Michnick, SW; Stefan, E (2015): In-vivo detection of binary PKA network interactions upon activation of endogenous GPCRs.
    In: Scientific Reports 5, Art. No. 11133. (DOI)

Zeitschriftenbeitrag (Proceedings Paper)
  • Hermann, B.; Liu, M.; Schmitner, N.; Maurer, B.; Meyer, D.; Weninger, W. J.; Drexler, W. (2015): Hybrid ultrahigh resolution optical coherence / photoacoustic microscopy.
    In: Proceedings of the International Society for Optical Engineering (SPIE) 9323, No. 93232N. (DOI) (Weblink)



Publikationen 2014

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)
  • Casari, Alessandro; Schiavone, Marco; Facchinello, Nicola; Vettori, Andrea; Meyer, Dirk; Tiso, Natascia; Moro, Enrico; Argenton, Francesco (2014): A Smad3 transgenic reporter reveals TGF-beta control of zebrafish spinal cord development.
    In: Developmental Biology 396/1, S. 81 - 93. (DOI) (Weblink)

Zeitschriftenbeitrag (Proceedings Paper)
  • Liu, Mengyang; Schmitner, Nicole; Sandrian, Michelle G.; Zabihian, Behrooz; Hermann, Boris; Salvenmoser, Willi; Meyer, Dirk; Drexler, Wolfgang (2014): In vivo spectroscopic photoacoustic tomography imaging of a far red fluorescent protein expressed in the exocrine pancreas of adult zebrafish.
    In: Proceedings of the International Society for Optical Engineering (SPIE) 8943, online. (DOI) (Weblink)

Zeitschriftenbeitrag (Meeting-Abstract)
  • Enthammer, Marion; Thurner, Marco; Khalid, Sana; Stuppner, Hermann; Cutress, Ramsey I.; Troppmair, Jakob (2014): TARGETING BAG-1-MEDIATED PROTEIN INTERACTIONS TO OVERCOME BRAF INHIBITOR RESISTANCE.
    In: Anticancer Research 34/10, S. 6219.



Publikationen 2013

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)
  • Liu, Mengyang; Schmitner, Nicole; Sandrian, Michelle G.; Zabihian, Behrooz; Hermann, Boris; Salvenmoser, Willi; Meyer, Dirk; Drexler, Wolfgang (2013): In vivo three dimensional dual wavelength photoacoustic tomography imaging of the far red fluorescent protein E2-Crimson expressed in adult zebrafish.
    In: Biomedical Optics Express 4/10, S. 1846 - 1855. (DOI) (Weblink)

  • Nuster, Robert; Schmitner, Nicole; Wurzinger, Gerhild; Gratt, Sibylle; Salvenmoser, Willi; Meyer, Dirk; Paltauf, Guenther (2013): Hybrid photoacoustic and ultrasound section imaging with optical ultrasound detection.
    In: Journal of Biophotonics  6/6-7, S. 549 - 559. (DOI) (Weblink)

  • Schmid, Benjamin; Shah, Gopi; Scherf, Nico; Weber, Michael; Thierbach, Konstantin; Campos, Citlali Perez; Roeder, Ingo; Aanstad, Pia; Huisken, Jan (2013): High-speed panoramic light-sheet microscopy reveals global endodermal cell dynamics.
    In: Nature Communications 4, No. 2207. (DOI) (Weblink)

  • Wilfinger, Armin; Arkhipova, Valeriya; Meyer, Dirk (2013): Cell type and tissue specific function of islet genes in zebrafish pancreas development.
    In: Developmental Biology 378/1, S. 25 - 37. (DOI) (Weblink)

  • Wurzinger, Gerhild; Nuster, Robert; Schmitner, Nicole; Gratt, Sibylle; Meyer, Dirk; Paltauf, Günther (2013): Simultaneous three-dimensional photoacoustic and laser-ultrasound tomography.
    In: Biomedical Optics Express 4/8, S. 1380 - 1389. (DOI) (Weblink)



Publikationen 2012

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)
  • Arkhipova, Valeriya; Wendik, Bjorn; Devos, Nathalie; Ek, O.; Peers, Bernard; Meyer, Dirk (2012): Characterization and regulation of the hb9/mnx1 beta-cell progenitor specific enhancer in zebrafish.
    In: Developmental Biology 365/1, S. 290 - 302. (DOI) (Weblink)

  • Dumortier, Julien G; Martin, Sandro; Meyer, Dirk; Rosa, Frederic M; David, Nicolas B (2012): Collective mesendoderm migration relies on an intrinsic directionality signal transmitted through cell contacts.
    In: PNAS. Proceedings of the National Academy of Sciences 109/42, S. 16945 - 16950. (DOI) (Weblink)

  • Nuster, Robert; Gratt, Sibylle; Passler, Klaus; Meyer, Dirk; Paltauf, Guenther (2012): Photoacoustic section imaging using an elliptical acoustic mirror and optical detection.
    In: Journal Of Biomedical Optics 17/3, No. 030503. (DOI)

  • Stueckemann, Tom; Wegleiter, Thomas; Stefan, Eduard; Naegele, Olivier; Tarbashevich, Katsiaryna; Boeck, Günther; Raz, Erez; Aanstad, Pia (2012): Zebrafish Cxcr4a determines the proliferative response to Hedgehog signalling.
    In: Development 139/15, S. 2711 - 2720. (DOI) (Weblink)

  • Voz, ML; Coppieters, W; Manfroid, I; Baudhuin, A; Von Berg, V; Charlier, C; Meyer, Dirk; Driever, W; Martial, JA; Peers, Bernard (2012): Fast homozygosity mapping and identification of a zebrafish ENU-induced mutation by whole-genome sequencing.
    In: PLoS One 7/4, S. e34671. (DOI) (Weblink)

Beitrag in Proceedingsband (Abstract)
  • Shivalingaiah, Giridhar; Moser, johannes; Sigl, Reinhard; Dayal, Anamika; Grabner, Manfred; Meyer, Dirk; Aanstad, Pia; Geley, Stephan (2012): Investigating the role of vertebrate FZR1 in proliferation and development.
    In: 4th Life Science Meeting of Innsbruck Universities. Book of Abstracts. Igls 27.09. - 28.09.2012. Innsbruck: Universität Innsbruck., S. 22.



Publikationen 2011

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)
  • Dünnhaupt, S.; Barthelmes, J.; Hombach, J.; Sakloetsakun, D.; Arkhipova, V.; Bernkop-Schnürch, A. (2011): Distribution of thiolated mucoadhesive nanoparticles on intestinal mucosa.
    In: International Journal of Pharmaceutics 408/1-2, S. 191 - 199.

  • Kimmel, Robin; Onder, Lucas; Wilfinger, Armin; Ellertsdottir, Elin; Meyer, Dirk (2011): Requirement for Pdx1 in specification of latent endocrine progenitors in zebrafish.
    In: BMC Biology 9/75, online. (Weblink)

  • Ott, Elisabeth; Norio, Paolo; Ritzi, Marion; Schildkraut, Carl; Schepers, Aloys (2011): The dyad symmetry element of Epstein-Barr virus is a dominant but dispensable replication origin.
    In: PLoS One 6/5, S. e18609. (DOI) (Weblink)

  • Pacho, F.; Zambruno G.; Calabresi V.; Kiritsi D.; Schneider H. (2011): Efficiency of translation termination in humans is highly dependent upon nucleotides in the neighbourhood of a (premature) termination codon.
    In: JOURNAL OF MEDICAL GENETICS 48/9, S. 640 - 644. (DOI)

  • Schulze, Rainer; Zangerl, Gerhard; Holotta, Markus; Handle, Florian; Meyer, Dirk; Nuster, Ro; Paltauf, Guenther; Scherzer, Otmar (2011): On the Use of Frequency-Domain Reconstruction Algorithms for Photoacoustic Imaging.
    In: Journal Of Biomedical Optics 16/8, No. 086002. (DOI)

  • Untergasser, Gerold; Martowicz, Agnieszka; Hermann, Martin; Töchterle, Sonja; Meyer, Dirk (2011): Distinct expression patterns of dickkopf genes during late embryonic development of Danio rerio.
    In: GENE EXPRESSION PATTERNS 11/8, S. 491 - 500. (Weblink)



Publikationen 2010

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)
  • Deutsch, MJ; Ott, E; Papior, P; Schepers A. (2010): The latent origin of replication of Epstein-Barr virus directs viral genomes to active regions of the nucleus.
    In: Journal of Virology 84/5, S. 2533 - 2546. (Weblink)

Zeitschriftenaufsatz (Review)
  • Kimmel, Robin; Meyer, Dirk (2010): Molecular Regulation of Pancreas development in Zebrafish.
    In: METHODS IN CELL BIOLOGY 100, S. 261 - 280. (Weblink)



Publikationen 2009

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)
  • Aanstad, Pia; Santos, Nicole; Corbit, Kevin C.; Scherz, Paul J.; Trinh, Le A.; Salvenmoser, Willi; Huisken, Jan; Reiter, Jeremy F.; Stainier, Didier Y.R. (2009): The Extracellular Domain of Smoothened Regulates Ciliary Localization and Is Required for High-Level Hh Signaling.
    In: Current Biology 19/June 23, S. 1034 - 1039. (Weblink)

  • Ott, I; Kircher, B; Bagowski, CP; Vlecken, DH; Ott, EB; Will, J; Bensdorf, K; Sheldrick, WS; Gust, R (2009): Modulation of the biological properties of aspirin by formation of a bioorganometallic derivative.
    In: Angewandte Chemie International Edition 48/6, S. 1160 - 1163. (Weblink)

  • VLECKEN, Danielle H.; TESTERINK, Janwillem; OTT, Elisabeth B.; SAKALIS, Philippe A.; JASPERS, Richard T.; BAGOWSKL, Christoph P. (2009): A critical role for myoglobin in zebrafish development.
    In: International Journal Of Developmental Biology 53/4, S. 517 - 524.

Medienbeiträge

Beitrag in Zeitung
  • Meyer, D.; Flatz, Ch.: Warum der Daumen der rechten Hand links ist.
    In: Universität Innsbruck - ipoint vom 27.05.2009. (Weblink)



Publikationen 2008

Herausgeberschaften

Proceedings (Herausgeberschaft)
  • Schwerte, T; Meyer, D (2008): Proceedings of the 1st Symposium "Image Mining", Obergurgl. Innsbruck: Universität Innsbruck.

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)
  • Bertola, LD; Ott, EB; Griepsma, S; Vonk, FJ; Bagowski, CP (2008): Developmental expression of the alpha-skeletal actin gene.
    In: BMC Evolutionary Biology 8, S. 166. (DOI)

  • Li, Q; Zhou, X; Guo, Y; Shang, X; Chen, H; Lu, H; Cheng, H; Zhou, R. (2008): Nuclear localization, DNA binding and restricted expression in neural and germ cells of zebrafish Dmrt3.
    In: BIOLOGY OF THE CELL 100/8, S. 453 - 463. (Weblink)

  • Ott, EB; van den Akker, NM; Sakalis, PA; Gittenberger-de Groot, AC; Te Velthuis, AJ; Bagowski, CP (2008): The lim domain only protein 7 is important in zebrafish heart development.
    In: DEVELOPMENTAL DYNAMICS 237/12, S. 3940 - 3952. (Weblink)

  • Zhou, X; Li, Q; Lu, H; Chen, H; Guo, Y; Cheng, H; Zhou, R (2008): Fish specific duplication of Dmrt2: characterization of zebrafish Dmrt2b.
    In: BIOCHIMIE 90/6, S. 878 - 887. (DOI)



Publikationen 2007

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)
  • Epting, D.; Vorwerk, S.; Hageman, A.; Meyer, D. (2007): Expression of rasgef1b in zebrafish.
    In: GENE EXPRESSION PATTERNS 7/4, S. 389 - 395.

  • Feldner, J.; Reimer, M.M.; Schweitzer, J.; Wendik, B.; Meyer, D.; Becker, T.; Becker, C.G. (2007): PlexinA3 Restricts Spinal Exit Points and Branching of Trunk Motor Nerves in Embryonic Zebrafish.
    In: The Journal of Neuroscience 27/18, S. 4978 - 4983. (DOI) (Weblink)

  • Ott, EB; Sakalis, PA; Marques, IJ; Bagowski, CP (2007): Characterization of the Enigma family in zebrafish.
    In: DEVELOPMENTAL DYNAMICS 236/11, S. 3144 - 3154. (Weblink)

Medienbeiträge

Beitrag in Publikumszeitschrift
  • Meyer, D.: Life Imaging in Innsbruck: Zebrafische leuchten für die Forschung.
    In: Chemiereport.at vom 17.02.2007. (Weblink)

Beitrag in Zeitung
  • Meyer, D.: 50.000 Fische für die biologisch medizinische Grundlagenforschung.
    In: Tiroler Tageszeitung vom 18.01.2007.

  • Meyer, D.: 50.000 Fische für die biologisch medizinische Grundlagenforschung.
    In: Universität Innsbruck - ipoint vom 18.01.2007. (Weblink)

Beitrag in (Web-)Radiosendung
  • Meyer, D.; Schwerte, T.: Zebrafischforschung in Tirol.
    In: ORF Radio - Ö1 vom 02.02.2007.

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