2024-11-26

Total Synthesis of Icumazole A Using a Modified Cadiot–Chodkiewicz Coupling

J. Buntine, S. Dasgupta, K. Dorney, O. Rubinstein, M. Salimimarand, J. M. White, M. A. Rizzacasa, Org. Lett. 2024, 26, 1062–1066.

2024-11-19

Catalytic Asymmetric Total Synthesis of (−)-Garryine via anEnantioselective Heck Reaction

C. Li, F. Lu, Y. Cai, C. Zhang, Y. Shao, Y. Zhang, X.-Y. Liu, Y. Qin, J. Am. Chem. Soc. 2024, 146, 1081−1088.

2024-11-12

Total Synthesis of (±)-Aspidophylline

W. Ren, Q. Wang, J. Zhu, Angew. Chem. Int. Ed. 2014, 53, 1818–1821.

2024-11-05

Total Synthesis of the Allenic Macrolide (+)-Archangiumide

J. L. Sutro, A. Fürstner, J. Am. Chem. Soc. 2024, 146, 2345–2350.

2024-10-29

Enantioselective Total Synthesis of (+)-Pedrolide

M. Fadel, E. M. Carreira, J. Am. Chem. Soc. 2023, 145, 15, 8332–8337

2024-10-22

Total Synthesis of Mollanol A

Y. Wang, R. Zhao, M. Yang, J. Am. Chem. Soc. 2022, 144, 15033–15037.

2024-10-15

Enantioselective Total Synthesis of (+)-Salvileucalin B

S. Levin, R. R. Nani, S. E. Reisman, J. Am. Chem. Soc. 2011, 133, 774–776.

2024-10-08

Synthesis of (–)-Picrotoxinin by Late-Stage Strong Bond Activation

S. W. M. Crossley, G. Tong, M. J. Lambrecht, H. E. Burdge, R. A. Shenvi, J. Am. Chem. Soc. 2020, 142, 11376–11381.

2024-10-01

Total Synthesis of (+)-Alstilobanine C

G. Li, N. Gaeng, C. Piemontesi, Q. Wang, J. Zhu, Angew. Chem., Int. Ed. 2021, 60, 12392.

2024-09-25

Asymmetric Total Synthesis of Clionastatins A and B

W. Ju, X. Wang, H. Tian, J. Gui, J. Am. Chem. Soc. 2021, 143, 13016–13021.

2024-09-18

Enantioselective Total Synthesis of (−)-Artatrovirenol A

R. Lavernhe, P. Domke, Q. Wang, J. Zhu, J. Am. Chem. Soc. 2023, 145, 24408−24415.

Total Synthesis of (–)-Retigeranic Acid A: A Reductive Skeletal Rearrangement Strategy

D. Sun, R. Chen, D. Tang, Q. Xia, Y. Zhao, C. Liu, H. Ding, J. Am. Chem. Soc. 2023, 145, 11927–11932.

Enantioselective Total Synthesis of (−)-Hunterine A Enabled by a Desymmetrization/Rearrangement Strategy

E. F. Hicks, K. Inoue, B. M. Stoltz, J. Am. Chem. Soc. 2024, 146, 4340–4345.

Total Synthesis of (–)-Okilactomycin

A. B. Smith, K. Basu, T. Bosanac, J. Am. Chem. Soc. 2007, 129, 14872–14874.

Total Synthesis of Chalcitrin

M. Yang, F. Yin, H. Fujino, S. A. Synder, J. Am. Chem. Soc. 2019, 141, 4515–4520.

Allenamide-Initiated Cascade [2+2+2] Annulation Enabling the Divergent Total Synthesis of (–)-Deoxoapodine, (–)-Kopsifoline D and (±)-Melotenine

L.-P. Zhao, P.-J. Li, L. Wang, Angew. Chem. Int. Ed. 2022, 61, e202207360.

Total Synthesis of atropurpuran

J. Gong, H. Chen, X.-Y. Liu, Z.-X. Wang, W. Nie, Y. Qin, Nat. Commun. 2016, 7, 12183.

Total Synthesis of Aspidophytine

K. C. Nicolaou, S. M. Dalby, U. Majumder, J. Am. Chem. Soc. 2008, 130, 14942–14943.

Divergent Synthesis of 17-nor-Cephalotane Diterpenoids through Developed Ynol-diene Cyclization

Z. Sun, X. Shu, F. Ma, A. Li, Y. Li, S. Jin, Y. Wang, H. Xiangdong, H. Angew. Chem. Int. Ed. 2024, e202407757.

Convergent and Efficient Total Synthesis of (+)-Heilonine enabled by C–H Functionalizations

Y. Jin, S. Hok, J. Bacsa, M. Dai, J. Am. Chem. Soc. 2024, 146, 1825-1831.

Total Synthesis of (–)-Strempeliopine

X. Zeng, D. L. Boger, J. Am. Chem. Soc. 2021, 143, 12412–12417.

A Convergent Total Synthesis of (+)-Ineleganolide

B. M. Gross, S. Han, S. C. Virgil, B. M. Stoltz, J. Am. Chem. Soc. 2023, 145, 7763-7767.

Enantioselective Total Synthesis of (—)-Himalensine A via a Palladium and 4-Hydroxyproline Cocatalyzed Desymmetrization of Vinyl-bromide-tethered Cyclohexanones.

R. Kučera, S. R. Ellis, K. Yamazakl, J. H. Cook, N. Chekshin, K. E. Christensen, T. A. Hamlin, D. J. Dixon, J. Am. Chem. Soc. 2023, 145, 5422-5430.

Total Synthesis of Five Thapsigargins: Guaianolide Natural Products Exhibiting Sub-Nanomolar SERCA Inhibition

S. P. Andrews, M. Ball, F. Wierschem, E. Cleator, S. Oliver, K. Högenauer, O. Simic, A. Antonello, U. Hünger, M. D. Smith, S. V. Ley, Chem. Eur. J. 2007, 13, 5688–5712.

Total Synthesis of ( )-Lepadiformine A Utilizing Hg(OTf)2-Catalyzed
Cycloisomerization Reaction

K. Nishikawa, S. Kikuchi, S. Ezaki, T. Koyama, H. Nokubo, T. Kodama, Y. Tachi, Y. Morimoto, Org. Lett. 2015, 17, 5772–5775.

Concise Total Synthesis of (-)-Bipolarolide

S. Sun, Q. Wei, Y. Liu, Z. Lu, J. Am. Chem. Soc. 2024, ASAP.

Total Synthesis of Aleutianamine

H. Yu, Z. P. Sercel, S. P. Rezgui, J. Farhi, S. C. Virgil, B. M. Stoltz, J. Am. Chem. Soc. 2023, 145, 25533-25537.

Total Synthesis of (−)-Batrachotoxin Enabled by a Pd/Ag-Promoted Suzuki–Miyaura Coupling Reaction

Y. Watanabe, H. Morozumi, H. Mutoh, K. Hagiwara, M. Inoue, Angew. Chem. Int. Ed. 2023, 62, e202309688.

Total Synthesis of Putative Melognine

Y. Irie, S. Yokoshima, J. Am. Chem. Soc. 2024, 146, 9526–9531.

Total Synthesis of Resiniferatoxin

V. H. Vasilev, L. Spessert, K. Yu, T. J. Maimone, J. Am. Chem. Soc. 2022, 144, 16332–16337.

Total Synthesis of (–)-Conidiogenone B

B. Xu, W. Xun, S. Su, H. Zhai, Angew. Chem. Int. Ed. 2020, 59, 16475–16479.

Asymmetric Total Synthesis of (2R)-Hydroxynorneomajucin, a Norsesquiterpene from Illicium jiadifengpi

C.J Dooley III, S. D. Rychnovsky, Org. Lett. 2022, 24, 3411–3415.

Asymmetric Total Synthesis of Propindilactone G

L. You, X.-T. Liang, L.-M. Xu, Y.-F. Wang, J.-J. Zhang, Q. Su, Y.-H. Li, B. Zhang, S.-L. Yang, J.-H. Chen, Z. Yang, J. Am. Chem. Soc. 2015, 137, 10120−10123.

Total Synthesis of (±)-Isostemofoline

A. S. Kende, T. L. Smalley, H. Huang, J. Am. Chem. Soc. 1999, 121, 7431–7432.

Platinum- and Gold-Catalyzed Rearrangement Reactions of Propargyl Acetates: Total Syntheses of (−)-a-Cubebene, (−)-Cubebol, Sesquicarene and Related Terpenes

A.Fürstner, P.Hannen, Chem. Eur. J. 2006, 12, 3006–3019.

Divergent Asymmetric Total Synthesis of (–)-Voacafricines A and B

R. Andres, Q. Wang, J. Zhu, Angew. Chem. Int. Ed. 2023, 62, e202301517.

Total Synthesis of (±)-Gelsemine

W. G. Earley, J. E. Jacobsen, A. Madin, G. P. Meier, C. J. O'Donnell, T. Oh, D. W. Old, L. E. Overman, M. J. Sharp, J. Am. Chem. Soc 2005, 127, 18046.

Total Synthesis, Relay Synthesis, and Structural Confirmation of the C18-Norditerpenoid Alkaloid Neofinaconitine

Y. Shi, J. T. Wilmot, L. U. Nordstrøm, D.S. Tan, D. Y. Gin, J. Am. Chem. Soc. 2013, 135, 14313–14320.

Total Synthesis of Kamebanin

T. Suzuki, W. Ikeda, A. Kanno, K. Ikeuchi, K. Tanino, Chem. Eur. J. 2023, 29, e20220351.

Enantioselective Syntheses of Wickerols A and B

J. Chung, J. S. Capani, M. Göhl, P. C. Roosen, C. D. Vanderwal, J. Am. Chem. Soc. 2023, 145, 6486–6497.

Synthesis of Pleuromutilin

N. J. Foy, S. V. Pronin, J. Am. Chem. Soc. 2022, 144, 10174–10179.

A Concise Total Synthesis of (+)-Waihoensene Guided by Quaternary Center Analysis

C. Peng, P. Arya, Z. Zhou, S. P. Snyder, Angew. Chem. Int. Ed. 2020, 59, 13521–13525.

Catalysis-Enabled 13-Step Total Synthesis of (−)-Peyssonnoside A

B. Xu, C. Liu, M. Dai, J. Am. Chem. Soc. 2022, 144, 19700–19703.

Streamlined Total Synthesis of Uncialamycin and Its Application to the Synthesis of Designed Analogues for Biological Investigations

K. C. Nicolaou, Y. Wang, M. Lu, D. Mandal, M. R. Pattanayak, R. Yu, A. A. Shah, J. S. Chen, H. Zhang, J. J. Crawford, L. Pasunoori, Y. B. Poudel, N. S. Chowdari, C. Pan, A. Nazeer, S. Gangwar, G. Vite, E. N. Pitsinos, J. Am. Chem. Soc. 2016, 138, 8235–8246.

Total Synthesis of Strychnine

G. S. Lee, G. Namkoong, J. Park, D. Y.-K. Chen, Chem. Eur. J. 2017, 23, 16189–16193.

Total Synthesis of Scabrolide A and Yonarolide

R. Serrano, Y. D. Boyko, L. W. Hernandez, A. Lotuzas, D. Sarlah, J. Am. Chem. Soc. 2023, 145, 8805–8809.

Enantioselective Total Synthesis of (+)-Dihydro-β-erythroidine

S. Clementson, M. Jessing, H. Pedersen, P. Vital, J. L. Kristensen, J. Am. Chem. Soc. 2019, 141, 8783−8786.

Bent π-Conjugation within a Macrocycle: Asymmetric Total Syntheses of Spirohexenolides A and B

L.-D. Guo, Y. Wu, X. Xu, Z. Lin, R. Tong, Angew. Chem. Int. Ed. 2023, e202316259.

Site-Specific Photochemical Desaturation Enables Divergent Syntheses of Illicium Sesquiterpenes

Y. Shen, L. Li, X. Xiao, S. Yang, Y. Hua, Y. Wang, Y.-W. Zhang, Y. Zhang, J. Am. Chem. Soc. 2021, 143, 3256–3263.

Total Synthesis of (+)-Fendleridine (Aspidoalbidine) and (+)-1-Acetylaspidoalbidine

E.L. Campbell, .M. Zuhl, C.M. Liu, D.L. Boger, J. Am. Chem. Soc. 2010, 132, 3009–3012.

Enantioselective Total Syntheses of the Cephalotaxus Alkaloids (−)-Fortuneicyclidins A and B and (−)-Cephalotine B

P.-Z. Sheng, Z.-B. Ni, L.-L. Li, K. Wei, H. Zhang, Y.-R. Yang, Org. Lett. 2023, 25, 7464–7469

Enantioselective Total Synthesis of (-)-Maoecrystal V

C. Zheng, I. Dubovyk, K. E. Lazarski, R. E. Thomson, J. Am. Chem. Soc. 2014, 136, 17750–17756

Asymmetric Synthesis of Cyclopamine, a Hedgehog (Hh) Signaling Pathway Inhibitor
A. Shao, W. Liu, M. Liu, H. He, Q.-L. Zhou, S.-F. Zhu, S. Gao, J. Am. Chem. Soc. 2023, DOI:10.1021/jacs.3c10362

Total Synthesis of (-)-Nummularine F
R. J. Heffner, J. Jiang, M. M. Joullie, J. Am. Chem. Soc. 1992, 114, 10181–10189.

Total Synthesis of dl-Coriolin

S. Danishefsky, R. Zamboni, M. Kahn, S. J. Etheredge, J. Am. Chem. Soc. 1980, 102, 2097–2098.

Total Synthesis of (+)-Gracilamine Based on an Oxidative Phenolic Coupling Reaction and Determination of its Absolute Configuration

M. Odagi, Y. Yamamoto, K. Nagasawa, Angew. Chem. Int. Ed. 2018, 57, 2229–2232

Total Synthesis of (+)-Aberrarone

Y. Wang, Y. Su, Y. Jia, J. Am. Chem. Soc. 2023, 145, 9459–9463.

Synthesis of a limonoid, azadiradione

E. J. Corey, R. W. Hahl, Tetrahedron Lett. 1989, 30, 3023–3026.

Total Synthesis of (±)-Trigonoliimine C via Oxidative Rearrangement of an Unsymmetrical Bis-Tryptamine

X. Qi, H. Bao, U. K. Tambar, J. Am. Chem. Soc. 2011, 133, 10050–10053.

Enantioselective Total Synthesis of (−)-Pavidolide B

P. Zhang, Z. Yan, Y. Li, J. Gong, Z. Yang,  J. Am. Chem. Soc. 2017, 139, 13989−13992.

Synthesis of ent-Ketorfanol via a C-H Alkenylation/Torquoselective 6𝝿 Electrocyclization Cascade

E. M. Phillips, T. Mesganaw, A. Patel, S. Duttwyler, B. Q. Mercado, K. N. Houk, J. A. Ellman, Angew. Chem. Int. Ed. 2015, 54, 12044-12048.

Total Synthesis of the Isodon Diterpene Sculponeatin N

B. J. Moritz, D. J. Mack, L. Tong, R. J. Thomson, Angew. Chem. Int. Ed. 2014, 53, 2988–2991.

Total Synthesis of Rubriflordilactone B

P. Yang, M. Yao, J. Li, Y. Li, A. Li, Angew. Chem. Int. Ed. 2016, 55, 6964 - 6968.

Total Synthesis of Isorosthin L and Isodenolin I

J. Ao, C. Sun, B. Chen, N. Yu, G. Liang, Angew. Chem. Int. Ed. 2022, 61, e202114489.

Scalable Total Synthesis of Portimine A and B Reveals the Basis of Their Potent and Selective Anti-cancer Acitvity

J. Tang, W. Li, T.-Y. Chiu, Z. Luo, C. T. Chong, Q. Wei, F. Martinez-Peňa, N. Gazaniga, Y. Y. See, L. L. Lairson, C. G. Parker, P. S. Baran, ChemRxiv, 2023. DOI: 10.26434/chemrxiv-2023-w286t.

Total Synthesis of Lyconesidine B

T. Kurose, C. Tsukano, T. Nanjo, Y. Takemoto, Org. Lett. 2021, 23, 676–681.

Concise asymmetric synthesis of (−)-bilobalide

M. A. Baker, R. M. Demoret, M. Ohtawa, R. A. Shenvi, Nature 2019, 575, 643–646.

Enantioselective Total Synthesis of (+)-Stephadiamine

B. Yang, G. Li, Q. Wang, J. Zhu, J. Am. Chem. Soc. 2023, 145, 5001–5006.

Asymmetric Total Synthesis of Illisimonin A

C. Etling, G. Tedesco, A. Di Marco and M. Kalesse, J. Am. Chem. Soc. 2023, 145, 7021–7029.

Total Synthesis of (+)-Fawcettidine

J. A. Kozak, G. R. Dake, Angew. Chem. Int. Ed. 2008, 47, 4221–4223.

Oxidative Entry into the Illicium Sesquiterpenes: Enantiospecific: Synthesis of (+)-Pseudoanisatin

K. Hung, M. Condakes, T. Morikawa, T. J. Maimone, J. Am. Chem. Soc. 2016, 138, 16616–16619.

Total Synthesis of (−)-Sinulariadiolide. A Transannular Approach

Z. Meng, A. Fürstner, J. Am. Chem. Soc. 2019, 141, 805–809.

Total Synthesis of Andirolide N via 8-a-Hydroxycarapin

A. W. Schuppe, T. R. Newhouse, J. Am. Chem. Soc. 2017, 139, 631–634.

Enantioselective Total Synthesis of (-)-Limaspermidine and (-)-Kopsinine by a Nitroaryl Transfer Cascade Strategy

B. Horst, D. S. Verdoorn, S. Hennig, G. van der Heijden, E. Ruijter, Angew. Chem., Int. Ed. 2022, 61, e202210592.

Total Synthesis of (±)-Waihoensene

H. Lee, T. Kang, H.-Y. Lee, Angew. Chem. Int. Ed. 2017, 56, 8254.

Total Synthesis of (–)-Gardmultimine A

P. Che, H. Yang, H. Zhang, W. Chen, Z. Zhang, J. Zhang, H. Li, X. Wang, X. Xie, X. She, Org. Lett. 2020, 22, 2022–2025.

Asymmetric Total Synthesis of (+)-6-epi-Castanospermine by the Stereoselective Formation of asyn,anti Acetylenic 2-Amino-1,3-diol Stereotriad

J. Louvel, C. Botuha, F. Chemla, E. Demont, F. Ferreira, A. Pérez-Luna, Eur. J. Org. Chem. 2010, 15, 2921–2926.

A Concise Synthesis of Pleurotin Enabled by a Nontraditional C-H Epimerization

J. F. Hoskin, E. J. Sorensen, J. Am. Chem. Soc. 2022, 144, 14042-14046.

Total Synthesis of the Tetracyclic Pyridinium Alkaloid epi-Tetradehydrohalicyclamine B

A. G. Dalling, G. Späth, A. Fürstner, Angew. Chem. Int. Ed. 2022, 61, e202209651.

Combined C-H Activation/Cope Rearrangement as a Strategic Reaction in Organic Synthesis: Total Synthesis of (-)-Colombiasin A and (-)-Elisapterosin B

H. M. L. Davies, X. Dai, M. S. Long, J. Am. Chem. Soc. 2006, 128, 7, 2485–2490.

Total Synthesis of the Akuammiline Alkaloid Picrinine

J. M. Smith, J. Moreno, B. W. Boal, N. K. Garg, J. Am. Chem. Soc. 2014, 136, 4504-4507.

10-Step Asymmetric Total Synthesis and Stereochemical Elucidation of (+)-Dragmacidin D

J. J. Jackson, H. Kobayashi, S. D. Steffens, A. Zakarian, Angew. Chem., Int. Ed. 2015, 54, 9971−9975.

Total Synthesis of Bipolamine I

X. Qiu, J. G. Pierce, J. Am. Chem. Soc. 2022, 144, 12638–12641.

The Total Synthesis of (+)-ShearilicineThe Total Synthesis of (+)-Shearilicine

D. E. Kim, Y. Zhu, S. Harada, I. Aguilar, A. E. Cuomo, M. Wang, T. R. Newhouse, J. Am. Chem. Soc. 2023, 145, 8, 4394–4399.

TTotal Synthesis of Abyssomicin C and atrop-Abyssomicin C

K. C. Nicolaou, S. T. Harrison, Angew. Chem. Int. Ed. 2006, 45, 3256–3260.

Total Synthesis of Dapholdhamine B and Dapholdamine B Lactone

L.-D. Guo, J. Hou, W. Tu, Y. Zhang, Y. Zhang, L. Chen, J. Xu, J. Am. Chem. Soc. 2019, 141, 11613–11720.

Enantioselective Synthesis of (-)-Maoecrystal V by Enantiodetermining C-H Functionalization

P. Lu, A. Mailyan, Z. Gu, D. M. Guptill, H. Wang, H.M.L. Davies, A. Zakarian, J. Am. Chem. Soc. 2014, 136, 17738–17749.

Total Synthesis of Vilmoraconitine

J. Ji, J. Chen, S. Qin, W. Li, J. Zhao, G. Li, H. Song, X. Y. Liu, Y. Qin, J. Am. Chem. Soc. 2023, 145, 3903–3908.

Total Synthesis of Ginkgolide C and Formal Syntheses of Ginkgolides A and B

M. Hébert, G. Bellavance, L. Barriault, J. Am. Chem. Soc. 2022, 144, 17792-17796.

Total Synthesis of Hirsutellone B

K. C. Nicolaou, D. Sarlah, T. R. Wu, W. Zhan, Angew. Chem. Int. Ed. 2009, 48, 6870–6874.

Total Synthesis of (−)-Daphenylline

B. Xu, B. Wang, W. Xun, F. G. Qiu, Angew. Chem. Int. Ed. 2019, 58, 5754–5757.

Total Synthesis of Yuzurine-type Alkaloid Daphgraciline

L.-X. Li, L. Min, T.-B. Yao, S.-X. Ji, C. Qiao, P.-L. Tian, J. Sun, C.-C. Li, J. Am. Chem. Soc. 2022, 144, 18823-18828.

Total Synthesis of Puberuline C

T. Shimakawa, S. Nakamura, H. Asai, K. Hagiwara, M. Inoue, J. Am. Chem. Soc. 2023, 145, 600–609.

Enantioselective Total Synthesis of (+)-Aberrarone

W. M. Amberg, E. M. Carreira, J. Am. Chem. Soc. 2022, 144, 15475–15479.

Total Synthesis of the Chlorinated Pentacyclic Indole Alkaloid (+)-Ambiguine G

L. Hu, V. H. Rawal, J. Am. Chem. Soc. 2021, 143, 10872–10875.

Total Synthesis of Farnesin

Y. Que, H. Shao, H. He, S. Gao, Angew. Chem. Int. Ed. 2020, 59, 7444–7449.

Synthetic Studies on Selective, Proapoptotic Isomalabaricane Triterpenoids Aided by Computational Techniques

Y. D. Boyko, C. J. Huck, S. Ning, A. S. Shved, C. Yang, T. Chu, E. J. Tonogai, P. J. Hergenrother, D. Sarlah, J. Am. Chem. Soc. 2021, 143, 2138-2155.

Total Synthesis of Diterpenoid Steenkrotin A

S. Pan, J. Xuan, B. Gao, A. Zhu, H. Ding, Angew. Chem. Int. Ed. 2015, 54, 6905–6908.

Total Synthesis of (-)-Morphine

H. Umihara, S. Yokoshima, M. Inoue, T. Fukuyama, Chem. Eur. J. 2017, 23, 6993 –6995.

Enantioselective Total Synthesis of (+)-Tricycloclavulone

H. Ito, M. Hasegawa, Y. Takenaka, T. Kobayashi, K. Iguchi, J. Am. Chem. Soc. 2004, 126, 4520–4521.

An eight-step gram-scale synthesis of (−)-jiadifenolide

H. Lu, M. Martinez, R. Shenvi, Nat. Chem. 2015, 7, 604–607.

Asymmetric Total Syntheses of Hypoestin A, Albolic Acid, and Ceroplastol II

Y. Wang, K. Xu, L. Min, C. Li, J. Am. Chem. Soc. 2022, 144, 10162–10167.

Total Synthesis of Carolacton, a Highly Potent Biofilm Inhibitor

T. Schmidt, A. Kirschning, Angew. Chem. Int. Ed. 2012, 51, 1063-1066.

Unified Total Synthesis of Pyrroloazocine Indole Alkaloids Sheds Light on Their Biosynthetic Relationship

F. M. Miloserdov, M. S. Kirillova, M. E. Muratore, A. M.  Echavarren , J. Am. Chem. Soc. 2018, 140, 5393–5400.

Tandem Decarboxylative Cyclization/Alkenylation Strategy for Total Syntheses of (+)-Longirabdiol, (–)-Longirabdolactone, and (–)-Effusin

J. Zhang, Z. Li, J. Zhuo, Y. Cui, T. Han, C. Li, J. Am. Chem. Soc. 2019, 141, 8372–8380.

14 Step Synthesis of (+)-Ingenol

L. Jørgensen, S. J. McKerrall, C. A. Kuttruff, F. Ungeheuer, J. Felding, P. S. Baran, Science 2013, 341, 878−882.

Asymmetric Total Synthesis of Hispidanin A

H. Deng, W. Cao, R. Liu, Y. Zhang, B. Liu, Angew. Chem. Int. Ed. 2017, 56, 5849.

Total Synthesis of Rameswaralide Utilizing a Pharmacophore-Directed Retrosynthetic Strategy

N.l J. Truax, S. Ayinde, J. O. Liu, D. Romo J. Am. Chem. Soc. 2022, asap. DOI: 10.1021/jacs.2c08245

Enantioselective Synthesis of Azamerone

M. L. Landry, G. M. McKenna, N. Z. Burns, J. Am. Chem. Soc. 2019, 141, 2867-2871.

Enantioselective Total Syntheses of Grayanane Diterpenoids: (−)-Grayanotoxin III, (+)-Principinol E, and (−)-Rhodomollein XX

L. Kong, H. Yu, M. Deng, F. Wu, Z. Jiang, T. Luo, J. Am. Chem. Soc. 2022, 144, 5268−5273.

Enantioselective Total Synthesis of Cotylenin A

M. Uwamori, R. Osada, R. Sugiyama, K. Nagatani, M. Nakada,  J. Am. Chem. Soc. 2020, 142, 5556–5561.

The Total Synthesis of (−)-Scabrolide A

N. J. Hafeman, S. A. Loskot, C. E. Reimann, B. P. Pritchett, S. C. Virgil, B. M. Stoltz, J. Am. Chem. Soc. 2020, 142, 8585−8590.

Synthesis of (+)-CP-263,114

C. Chen, M. E. Layton, S. M. Sheehan, M. D. Shair, J. Am. Chem. Soc. 2000, 122, 7424–7425.

Enantioselective Total Synthesis of (+)-Euphorikanin A

M. J. Classen, M. N. A. Böcker, R. Roth, W. M. Amberg, E. M. Carreira, J. Am. Chem. Soc. 2021, 143, 8261–8265.

Total Syntheses of (–)-Acutumine and (–)-Dechloroacutumine

S. M. King, N. A. Calandra, S. B. Herzon, Angew. Chem. Int. Ed. 2013, 52, 3642–3645.

Total Synthesis of (+)-6-epi-Ophiobolin A

D. Q. Thach, Z. G. Brill, H. K. Grover, K. V. Esguerra, J. K. Thompson, T. J. Maimone
Angew. Chem. Int. Ed. 2020, 59, 1532-1536.

Asymmetric Total Syntheses of (+)-Davisinol and (+)-18-Benzoyldavisinol: A HAT-Initiated Transannular Redox Radical Approach

K. Yu, F. Yao, Q. Zeng, H. Xie, H. Ding, J. Am. Chem. Soc. 2010, 132, 8506–8512.

Formal Syntheses of (-)- and (+)-Phalarine by a hypervalent iodine mediated oxidative double cyclization

H. Ding, D. Y.-K. Chen, Angew. Chem. Int. Ed. 2011, 50, 676-679.

Total Synthesis of Enantiopure Phalarine via a Stereospecific Pictet-Spengler Reaction: Traceless Transfer of Chirality from L-Tryptophan

J. D. Trzupek, D. Lee, B. M. Crowley, V. M. Marathias, S. J. Danishefsky,  J. Am. Chem. Soc. 2010, 132, 8506–8512.

Total Synthesis of Alkaloid (()-G. B. 13 Using a Rh(I)-Catalyzed Ketone Hydroarylation and Late-Stage Pyridine Reduction

K. K. Larson, R. Sarpong, J. Am. Chem. Soc. 2009, 131, 13244–13245.

Total Synthesis of (+)-Cochlearol B by an Approach Based on a Catellani Reaction and Visible-Light-Enabled [2+2] Cycloaddition

A. D. Richardson, R. V. Trenton,  E. F. Traficante, K. J. Glover, C. S. Schindler, DOI: 10.1002/anie.202201213.

Total Syntheses of (+)-Aquatolide and Related Humulanolides

K.-I. Takao, H. Kai, A. Yamada, Y. Fukushima, D. Komatsu, A. Ogura, K. Yoshida, Angew. Chem. Int. Ed. 2019, 58, 9851–9855.

Total Synthesis of Daphenylline, Daphnipaxianine A, and Himalenine D

Y. Chen, W. Zhang, L. Ren, J. Li, A. Li, Angew. Chem. Int. Ed. 2018, 130, 964–968.

Asymmetric Total Synthesis of (–)-Phaeocaulisin A

A. Péter, G. E. M. Crisenza, D. J. Procter, J. Am. Chem. Soc. 2022, 144, 7457-7464.

Total Synthesis of Haterumaimide J

S. E. Michalak, S. Nam, D. M. Kwon, D. A. Horne, C. D. Vanderwal, J. Am. Chem. Soc. 2019, 141, 9202–9206.

Total Synthesis of (±)-Isophellibiline

R. L. Funk, J. Belmar, Tetrahedron Lett. 2012, 53, 176–178.

Two-Stage Syntheses of Clionastatins A and B

H. Cui, Y. Shen, Y. Chen, R. Wang, H. Wei, P. Fu, X. Lei, H. Wang, R.Bi, Y. Zhang, J. Am. Chem. Soc. 2022, 144, 8938-8944.

Asymmetric Total Synthesis of (2R)‑Hydroxynorneomajucin, a Norsesquiterpene from Illicium jiadifengpi

C. Dooley, S. Rychnovsky, Org. Lett. 2022, 24, 3411-3415.

Deconstructive Asymmetric Total Synthesis of Morphine-Family Alkaloid (-)-Thebainone A

S. H. Hou, A. Prichina, G. Dong, Angew. Chem. Int. Ed. 2021, 60, 13057-13064.

Asymmetric Total Synthesis of Laurallene

F. Yoshimura, T. Okada, K. Tanino, Org. Lett. 2019, 21, 559-562

β-Ketoesters as Mono- or Bisnucleophiles: A concise Enantioselective Total synthesis of (–)-Englerin A and B

L. Guo, B. Plietker, Angew. Chem. Int. Ed. 2019, 58, 8346-8350.

Total Synthesis of (±)-Perophoramide

J. R. Fuchs, R. L. Funk J. Am. Chem. Soc. 2004, 126, 5068-5069

The total synthesis of (±)-11-O-debenzoyltashironin

S. P. Cook, A. Polara, S. J. Danishefsky, J. Am. Chem. Soc. 2006, 128, 16440-16441.

Total Synthesis of Vinigrol

T. J. Maimone, J. Shi, S. Ashida, P. S. Baran, J. Am. Chem. Soc. 2009, 131, 17066-17067.

Total Synthesis of Gukulenin B via Sequential Tropolone Functionalizations

K. C. Nicolaou, Ruocheng Yu, Zhaoyong Lu, and Fernando G. Alvarez, J. Am. Chem. Soc. 2022, 144, 5190-5196.

Synthesis of Swinhoeisterol A, Dankasterone A and B, and Periconiastone A by Radical Framework Reconstruction

F. L. Duecker, R. C. Heinze, P. Heretsch, J. Am. Chem. Soc. 2020, 142, 104-108.

Asymmetric Total Synthesis of Norzoanthamine

Z. Xin, H. Wang, H. He, X. Zhao, S. Gao, Angew. Chem. Int. Ed. 2021, 60, 12807-12812.

Bidirectional Total Synthesis of Phainanoid A via Strategic Use of Ketones

J. Xie, X. Liu, N. Zhang, S. Choi, G. Dong, J. Am. Chem. Soc. 2021, 143, 19311–19316.

Asymmetric Total Synthesis of Indole Diterpenes Paspalicine, Paspalinine, and Paspalinine-13-ene

L.-D. Guo, Z. Xu, R. Tong, Angew. Chem. Int. Ed. 2022, 61, e202115384.

Total Synthesis of (−)-Rhodomollanol A

J. Gao, P. Rao, K. Xu, S. Wang, Y. Wu, C. He, H. Ding, J. Am. Chem. Soc. 2020, 142, 4592-4597.

Total Synthesis of (±)-Leonuketal

P. S. Grant, D. P. Furkert, M. A. Brimble, Org. Lett. 2020, 22, 8735-8740.

Asymmetric Total Synthesis of Shizukaol J, Trichloranoid C and Trishizukaol A

X. Wang, Z. Wang, X. Ma, Z. Huang, K. Sun, X. Gao, S. Fu, B. Liu, Angew. Chem. Int. Ed. 2022, DOI: 10.1002/anie.202200258.

Total Synthesis of (−)-Daphnezomines A and B

G. Xu, J. Wu, L. Li, Y. Lu, C. J. Li, J. Am. Chem. Soc. 2020, 142, 15240-15245.

A Short Synthesis of Delavatine A Unveils New Insights into Site-Selective Cross-Coupling of 3,5-Dibromo-2-pyrone

V. Palani, C. L. Hugelshofer, L. Kevlishvili, P. Liu, R. Sarpong, J. Am. Chem. Soc. 2019, 141, 2652−2660.

A biomimetic total synthesis of (+)-intricarene 

B. Tang, C. D. Bray, G. Pattenden, Tetrahedron Lett. 2006, 47, 6401–6404.

Total Synthesis of (+)-Hinckdentine A

K. Douki, H. Ono, T. Taniguchi, J. Shimokawa, M. Kitamura, T. Fukuyama, J. Am. Chem. Soc. 2016, 138, 14578−14581

Ir-Catalyzed Asymmetric Total Syntheses of Bisdehydrotuberostemonine D, Putative Bisdehydrotuberostemonine E and Structural Revision of the Latter

Y. Deng, X. Liang, K. Wei, Y. R. Yang, J. Am. Chem. Soc. 2021, ASAP

Total Synthesis of Nesteretal A

Y. Kawamoto, H. Kitsukawa, T. Kobayashi, H. Ito, Org. Lett. 2021, 23, 7074–7078.

Asymmetric Total Syntheses of Schizozygane Alkaloids
W. Zhou, T. Zhou, M. Tian, Y. Jiang, J. Yang, S. Lei, Q. Wang, C. Zhang, H. Qiu, L. He, Z. Wang, J. Deng, M. Zhang, J. Am. Chem. Soc. 2021, DOI: 10.1021/jacs.1c10279.

Divergent Synthesis of Natural Derivatives of (+)-Saxitoxin Including 11-Saxitoxinethanoic Acid

J. R. Walker, J. E. Merit, R. Thomas-Tran, D. T. Y. Tang, J. Du Bois, Angew. Chem. Int. Ed. 2019, 58, 1689–1693.

Asymmetric Total Synthesis of Pre-schisanartanin C

Y.-L. Jiang, H.-X. Yu, Y. Li, P. Qu, Y.-X. Han, J.-H. Chen, Z. Yang, J. Am. Chem. Soc. 2020, 142, 573–580. 

Asymmetric Total Synthesis of (+)-Mannolide C

Q. Ao, H.-J. Zhang, J. Zheng, X. Chen, H. Zhai, Angew. Chem. Int. Ed. 2021, 60, 21267–21271.

Total Synthesis of (±)-Rocaglamide via Oxidation-Initiated Nazarov Cyclization

J. A. Malona, K. Cariou, W. T. Spencer, III, and A. J. Frontier, J. Org. Chem. 2012, 77, 1891–1908

Collective Asymmetric Total Synthesis of C-11 Oxygenated Cephalotaxus Alkaloids

J. H. Kim, H. Jeon, C. Park,  S. Park, S. Kim, Angew. Chem. Int. Ed. 2021, 60, 12060–12065.

Total Synthesis of (±)-Meloscine

Y. Hayashi, F. Inagaki, C. Mukai, Org. Lett. 2011, 13, 1778.

An Efficient, Stereocontrolled, Total Synthesis of the Orchidaceae Alkaloid (±)-Dendrobine

C. H. Lee, M. Westling, T. Livinghouse, A. C. Williams, J. Am. Chem. Soc. 1992, 114, 4089–4095.

Total Synthesis and Structural Revision of a Harziane Diterpenoid

M. Hönig, E. M. Carreira, Angew. Chem. Int. Ed. 2020, 59, 1192.

Concise Total Synthesis of Peyssonnoside A

G. A. Chesnokov, K. Gademann,  J. Am. Chem. Soc. 2021, 143, 14083–14088.

Total Synthesis of Limaol

S. N. Hess, X. Mo, C. Wirtz, and A. Fürstner, J. Am. Chem. Soc. 2021, 143, 6, 2464–2469.

Total Synthesis of ( )-Jiadifenin

X. Cheng, G. C. Micalizio, J. Am. Chem. Soc. 2016, 138, 1150.

Enantioselective Total synthesis of (+)-Garsubellin A

D. Jang, M. Choi, J. Chen, C. Lee, Angew. Chemie Int. Ed. 2021, ASAP.

Total Syntheses of the C19 Diterpenoid Alkaloids (−)-Talatisamine, (−)-Liljestrandisine, and (−)-Liljestrandinine by a Fragment Coupling Approach

A. R. Wong, N. J. Fastuca, V. W. Mak, J. K. Kerkovius, S. M. Stevenson and S. E. Reisman
ACS Cent. Sci. 2021, ASAP.

 Asymmetric Total Synthesis of (−)-Spirochensilide A

X.-T. Liang, J.-H. Chen, Z. Yang, J. Am. Chem. Soc. 2020, 142, 8116–8121.

 Concise and Stereoselective Synthesis of Annotinolides C, D, and E

P. Qu, S. Snyder, J. Am. Chem. Soc. 2021, 143, 11951–11956.

Total Synthesis of Putative Chagosensine

M. Heinrich, J. J. Murphy,  M. K. Ilg, A. Letort, J. Frasz, P. Philipps, A. Fürstner, Angew. Chem. Int. Ed. 2017, 57, 13578–13581.

Total Synthesis of (–)-Tubingensin B Enabled by the Strategic Use of an Aryne Cyclization

M. A. Corsello, J. Kim, N. K. Garg, Nat. Chem. 2017, 9, 944-949.

Tandem C–H oxidation/cyclization/rearrangement and its application to asymmetric syntheses of (–)-brussonol and (–)-przewalskine E

Z. Jiao, Y. Tu, Q. Zhang, W. Liu, S. Zhang, S. Wang, F. Zhang, S. Jiang, Nat. Commun. 2015, 7332, 6.

Enantioselective Total Synthesis and Structural Revision of Dysiherbol A

J. Baars, I. Grimm, D. Blunk, J.-M. Neudörfl, H.-G. Schmalz, Angew. Chem. Int. Ed. 2021, 60, 14915–14920.

Asymmetric Total Synthesis and Biosynthetic Implications of Perovskones, Hydrangenone, and
Hydrangenone B

B. Yang, G. Wen, Q. Zhang, M. Hou, H. He, S. Gao, J. Am. Chem. Soc. 2021, 143, 6370–6375.

Total Synthesis of (–)-Strictosidine

S. M. Anthony, V. Tona, Y. Zou, L. A. Morrill, J. M. Billingsley, M. Lim, Y. Tang, K. N. Houk, N. K. Garg,
J. Am. Chem. Soc. 2021, 143, 7471–7479.

Enantioselective Synthesis of Iboga Alkaloids and Vinblastine Via Rearrangements of
Quaternary Ammoniums

Y. Zhang, Y. Xue, G. Li, H. Yuan, T. Luo, Chem. Sci. 2016, 7, 5530–5536.

Total Synthesis of the Meroterpenoid Manginoid A as Fueled by a Challenging
Pinacol Coupling and Bicycle-forming Etherification

Y.-A. Zhang, A. Milkovits, V. Agarawal, C. A. Taylor, S. A. Snyder, Angew. Chem. In. Ed 2021, 60, 11127-11132.

Clinical targeting of HIV capsid protein with a long-acting small molecule

J. O. Link, M. S. Rhee, W. C. Tse et al, Nature 2020, 584, 614–618.

Synthesis of Brevianamide A and B

R. C. Godfrey, N. J. Green, G. S. Nichol and A. L. Lawrence, Nat. Chem. 2020, 12, 615–619.

 Enantioselective Total Synthesis of (+)-Wortmannin

Y. Guo, T. Quan, Y.Lu, T. Luo, J. Am. Chem. Soc. 2017, 139, 6815–6818.

The total synthesis of indolizomycin

G. Kim, M. Y. Cho-Moyer, S. J. Danishefsky, G. K. Schulte, J. Am. Chem. Soc. 1990, 115, 30-39.

Synthesis of Aspidodispermine via Pericyclic Framework Reconstruction

F. Reuß, P. Heretsch, Org. Lett. 2020, 22, 3956–3959.

Enantioselective Total Synthesis of Macfarlandin C

T. K. Allred, A. P. Dieskau, P. Zhao, G. L. Lackner, L. E. Overman, Angew. Chem. Int. Ed. 2020, 59, 6268-6272.

Total Synthesis of (+)-Vallesamidineand (+)-14,15-Dehydrostrempeliopine

X. Zhang, J. C. Anderson, Angew.Chem. Int. Ed. 2019, 58,18040 –18045.

Total Synthesis of (−)-Jiadifenin

Y. Yang, X. Fu, J. Chen, H. Zhai, Angew. Chem. Int. Ed. 2012, 51, 9825–9828.

Total Syntheses of Berkeleyone A and Terretonin L

G. Xu, M. Elkin, D. J. Tantillo, T. R. Newhouse, T. J. Maimone, Angew. Chem. Int. Ed. 2017, 56, 12498; C. P. Ting, G. Xu, X. Zeng, T. J. Maimone, J. Am. Chem. Soc. 2016, 138, 14868.

Total Synthesis of (±)-Streptonigrin

T. J. Donohoe, C. R. Jones, L. C. A. Barbosa, J. Am. Chem. Soc. 2011, 133, 16418−16421.

Total Synthesis of the Marine Diterpenoid Blumiolide C

C. Hamel, E. V. Prusov, J. Gertsch, W. B. Schweizer, K. H Altmann, Angew. Chem. Int. Ed. 2008, 47, 10081−10085.

Total Synthesis of (±)-11‑O‑Debenzoyltashironin

J. Tong, T. Xia, B. Wang, Org. Lett. 2020, 22, 2730−2734.

Total Synthesis of Leucascandrolide A

Y. Wang, J. Janjic, S. A. Kozmin J. Am, Chem. Soc. 2002, 124, 13670–13671; S. A. Kozmin, Org. Lett. 2001, 3, 755–758.

Total Synthesis and Stereochemical Reassignment of (±)-Indoxamycin B

O. F. Jeker, E. M. Carreira, Angew. Chem. Int. Ed. 2012, 51, 3474-3477.

Total Synthesis of Rapamycin

M. L. Maddess, M. N. Tackett, H. Watanabe, P. E. Brennan, C. D. Spilling, J. S. Scott, D. P. Osborn, S. V. Ley, Angew. Chem. Int. Ed. 2007, 46, 591–597.

Total Synthesis of the Diterpene Waihoensene

L.-C. Rosenbaum, M. Häfner, T.Gaich, Angew. Chem. Int. Ed. 2021, 60, 2939.

Mimicking oxidative radical cyclization of lignan biosynthesis using redox-neutral photocatalysis

Zheng, H; Lumb, J. P., Nat. Chem. 2021, 13, 24–32.

Protecting-Group-Free Syntheses of ent-Kaurane Diterpenoids: [3+2+1] Cycloaddition/Cycloalkenylation Approach

Wang, J.; Hong, B.; Hu D.-C.; Kadonaga, Y.; Tang, R.-Y.; Lei, X.-G., J. Am. Chem. Soc. 2020, 142, 2238–2243.

Discovery of NVP-BYL719 a potent and selective phosphatidylinositol-3 kinase alpha inhibitor selected for clinical evaluation

Furet, P.; Guagnano, V.; Fairhurst, R. A.; Imbach-Weese, P.; Bruce, I.; Knapp, M.; Fritsch, C.; Blasco, F.; Blanz, J.; Aichholz, R.; Hamon, J.; Fabbro, D.; Caravatti, G., Bioorg. Med. Chem. Lett. 2013, 23, 3741–3748.

Total Synthesis of (–)-Crinipellin A

T. Kang, S. B. Song, W. Kim, B. G. Kim, H. Lee, J. Am. Chem. Soc. 2014, 136, 10274–10276.

Synthesis of Eupalinilide E, a Promoter of Human Hematopoietic
Stem and Progenitor Cell Expansion

T. C. Johnson, M. R. Chin, T. Han, J. P. Shen, T. Rana, D. Siegel, J. Am. Chem. Soc. 2016, 138, 6068-6073.

 Total Synthesis of (–)-Himalensine A

H. Shi, I. N. Michaelides, B. Darses, P. Jakubec, Q. N. N. Nguyen, R. S. Paton, R. S. D. J. Dixon, J. Am. Chem. Soc. 2017, 139, 17755–17758.

Total Synthesis of (+)-Hapeforin G

W. Zhang, Z. Zhang, J.-C. Tang, J.-T. Che, H.-Y. Zhang, J.-H. Chen, Z. Yang,  J. Am. Chem. Soc. 2020, 142, 19487–19492.

Total Synthesis of Liangshanone

H.-X. Huang, F. Mi, C. Li, H. He, F.-P. Wang, X.-Y. Liu, Y. Qin, Angew. Chem. Int. Ed. 2020, early view.

Total Synthesis of Bryostatin 1

P. A. Wender, C. T. Hardman, S. Ho, M. S. Jeffreys, J. K. Maclaren, R. V. Quiroz, S. M. Ryckbosch,
A. J. Shimizu, J. L. Sloane, M. C. Stevens, Science 2017, 358, 218–223.

Synthesis of Streptolydigin, a Potent Bacterial RNA Polymerase Inhibitor

S.V. Pronin, S. A. Kozmin, J. Am. Chem. Soc. 2010, 132, 14394.

Total Synthesis of Tagetitoxin

C. He, H. Chu, T. P. Stratton, D. Kossler, K. J. Eberle, D. T. Flood, P. S. Baran, J. Am. Chem. Soc. 2020, 142, 13683–13688.

Asymmetric Total Synthesis of Cyclocitrinol

J. Liu, J. Wu, J.-H. Fan, X. Yan, G. Mei, C.-C. Li, J. Am. Chem. Soc. 2018, 140, 5365–5369.

Total Synthesis of (–)-Nakadomarin A

S. Bonazzi, B. Cheng, J. S. Wzorek, D. A. Evans, J. Am. Chem. Soc. 2013, 135, 9338–9341.

Total Synthesis and Anti-Cancer Activity of All Known Communesin Alkaloids and Related Derivatives

M. M. Pompeo, J. H. Cheah, M. Movassaghi, J. Am. Chem. Soc. 2019, 141, 14411–14420.

Synthesis of (–)-Fumagillin

D. F. Taber, T. E. Christos, A. L. Rheingold, I. A. Guzei, J. Am. Chem. Soc. 1999, 121, 5589–5590.

Total Synthesis of (±)-Chloranthalactone A

G. Yue, L. Yang, C. Yuan, X. Jiang, B. Liu, Org. Lett. 2011, 13, 5406–5408.

Total Syntheses of Dibromophakellstatin and Dibromoangelaspongin

K. S. Feldman, A. P. Skoumbourdis, Org. Lett. 2005, 7, 929–931; K. S. Feldman, M. D. Foor, J. Am. Chem. Soc. 2008, 130, 14964–14965.

Total Synthesis of Talatisamine

D. Kamakura, H. Todoroki, D. Urabe, K. Hagiwara, M. Inoue, Angew. Chem. Int. Ed. 2020, 59, 479–486.

Nineteen-Step Total Synthesis of (+)-Phorbol

S. Kawamura, H. Chu, J. Felding, P. S. Baran, Nature 2016, 532, 90–93.

Total Synthesis and Structural Revision of Callipeltoside C

J. Carpenter, A. B. Northrup, d. Chung, J. J. M. Wiener, S.-G. Kim, D. W. C. MacMillan, Angew. Chem. Int. Ed. 2008, 47, 3568.

Total Syntheses of (–)-Deoxoapodine, (–)-Kapsifoline D and (–)-Beninine

Y.-G. Zhou, H. N. C. Wong, X.-S. Peng, J. Org. Chem. 2020, 85, 967–976.

Total Synthesis of Echinopines A and B

P. A. Peixoto, J.-A. Richard, R. Severin, D. Y.-K. Chen, Org. Lett. 2011, 13, 5724–5727.

Total Syntheses of (–)-Conidiogenone B, (–)-Conidiogenone, and (–)-Conidiogenol

B. Xu, W. Xun, S. Su, H. Zhai, Angew. Chem. Int. Ed. 2020, 59, 1–6.

Total Synthesis of Elisapterosin B

N. Waizumi, A. R. Stankovic, V. H. Rawal, J. Am. Chem. Soc. 2003, 125, 13022–13023.

Synthesis of Anhydroryanodol

K. Du, M. J. Kier, Z. D. Stempel, V. Jeso, A. L. Rheingold, G. C. Micalizio, J. Am. Chem. Soc. 2020, ASAP, https://doi.org/10.1021/jacs.0c05766.

Synthesis of Waihoensene

Y. Qu, Z. Wang, Z. Zhang, W. Zhang, J. Huang, Z. Yang, J. Am. Chem. Soc. 2020, 142, 6511.

Spiroacetal Formation through Telescoped Cycloaddition and Carbon–Hydrogen Bond
Functionalization: Total Synthesis of Bistramide A

X. Han, P. E. Floreancig, Angew. Chem. Int. Ed. 2014, 53, 11075–11078.

Total Synthesis of Bryostatin 3

B. M. Trost, Y. Wang, A. K. Buckl, Z. Huang, M. H. Nguyen, O. Kuzmina, Science 2020, 368, 1007.

An Enantiospecific Route to (+)- and (–)-Chrysanthemum Dicarboxylic Acids

B. J. Fitzsimmons, B. Fraser-Reid, Tetrahedron 1984, 40, 1279–1287.

Asymmetric Total Synthesis of Mycoleptodiscin A

S. Zhou, H. Chen, Y. Luo, W. Zhang, A. Li, Angew. Chem. Int. Ed. 2015, 54, 6878–6882.

Total Synthesis of (+)-Haplophytine

H. Ueda, H. Sato, K. Matsumoto, K. Sugimoto, T. Fukuyama, H. Tokuyama, Angew. Chem. Int. Ed. 2009, 48, 7600.

Total Synthesis of Merochlorin

M. Brandstätter, M. Freis, N. Huwyler, E. M. Carreira, Angew. Chem. Int. Ed. 2019, 58, 2490–2494.

Component-based Synthesis of Trioxacarcin A

T. Magauer, D. J. Smaltz, A. G. Myers, Nat. Chem. 2013, 5, 886–893.

Total Synthesis of (–)-Batrachotoxinin A: A Local-Desymmetrization
Approach

Y. Guo, Z. Guo, J.-T. Lu, R. Fang, S.-C. Chen, T. Luo, J. Am. Chem. Soc. 2020, 142, 3675–3679.

Divergent Synthesis of Antiviral Diterpenes Wickerols A and B

J. Deng, Y.Ning, H. Tian, J. Gui, J. Am. Chem. Soc. 2020, 142, 4690–4695.

Total Synthesis of Gelsemoxonine

J. Shimokawa, T. Harada, S. Yokoshima, T. Fukuyama, J. Am. Chem. Soc. 2011, 133, 17634–17637.

A 16-step synthesis of the isoryanodane diterpene (+)-perseanol

A. Han, Y. Tao, S. E. Reisman, Nature 2019, 573, 563–567.

Total Synthesis of (–)-Allosecurinine

A. B. Leduc, M. A. Kerr, Angew. Chem. Int. Ed. 2008, 47, 7945–7948.

Diastereoselective Total Synthesis of (±)-Schindilactone A

Q. Xiao, W.i-W. Ren, Z.-X. Chen, T.-W. Sun, Y. Li, Q.-D. Ye, J.-X. Gong, F.-K. Meng, L. You, Y.-F. Liu, M.-Z. Zhao, L.-M. Xu, Z.-H. Shan, Y. Shi,Y.-F. Tang, J.-H. Chen, Z. Yang, Angew. Chem. Int. Ed. 2011, 50, 7373–7377.

Total Synthesis of (–)-Oridonin: An Interrupted Nazarov Approach

L. Kong, F. Su, H. Yu, Z. Jiang, Y. Lu, T. Luo, J. Am. Chem. Soc. 2019, 141, 20048–20052.

Total Synthesis of Jatrophatrione

L. A. Paquette, S. D. Edmondson, N. Monck, R. D. Rogers, J. Org. Chem. 1999, 64, 3255–3265;
L. A. Paquette, S. Nakatani, T. M. Zydowsky, S. D. Edmondson, L.-Q. Sun, R. Skerlj, J. Org. Chem. 1999, 64, 3244–3254;
L. A. Paquette, J. Yang, Y. O. Long, J. Am. Chem. Soc. 2002, 124, 6542–6543.

Synthesis of Myrocin G

C. Economou, M. Tomanik, S. B. Herzon, J. Am. Chem. Soc. 2018, 140, 16058.

Novel DNA Gyrase Inhibiting Spiropyrimidinetriones with a Benzisoxazole Scaffold

G. S. Basarab, P. Brassil, P. Doig, V. Galullo, H. B. Haimes, G. Kern, A. Kutschke, J. McNulty, V. J. A. Schuck, G. Stone, M. Gowravaram, J. Med. Chem. 2014, 57, 9078–9095.

Total Synthesis of Hyperforin

C. P. Ting, T. J. Maimone, J. Am. Chem. Soc. 2015, 137, 10516.

A 15-step Synthesis of (+)-Ryanodol

K. V. Chuang, C. Xu, S. E. Reisman, Science 2016, 353, 912–915.

Total Synthesis of Isomalabaricane Triterpenoids

Y. D. Boyko, C. J. Huck, D. Sarlah, J. Am. Chem. Soc. 2019, 141, 14131–14135.

Total Synthesis of Viridin and Viridiol

Y. Ji, Z. Xin, H. He, S. Gao, J. Am. Chem. Soc. 2019, 141, 16208–16212.

Total Synthesis of the Diterpenoid Alkaloid Arcutinidine Using a Strategy Inspired by Chemical Network Analysis

K. R. Owens, S. V. McCowen, K. A. Blackford, S. Ueno, Y. Hirooka, M. Weber, R. Sarpong,
J. Am. Chem. Soc. 2019, 141, 13713–13717.

Asymmetric Total Synthesis of (–)-Vinigrol

L. Min, X. Lin, C.-C. Li, J. Am. Chem. Soc. 2019, 141, 15773–15778.

Calyciphylline B-Type Alkaloids: Total Syntheses of (–)-Daphlongamine H and (–)-Isodaphlongamine H

C. L. Hugelshofer, V. Palani, R. Sarpong, J. Am. Chem. Soc. 2019, 141, 8431–8435.

Total Synthesis of (+)-Halichlorine: An Inhibitor of VCAM-1 Expression

D. Trauner, J. B. Schwarz, S. J. Danishefsky, Angew. Chem. Int. Ed. 1999, 38, 3542–3545.

Enantioselective Total Synthesis of Caldaphnidine O via
a Radical Cyclization Cascade

L.-D. Guo, J. Hu, Y. Zhang, W. Tu, Y. Zhang, F. Pu, J. Xu, J. Am. Chem. Soc. 2019, 141, 13043.

A Concise Total Synthesis of (-)-Himalensine A

Y. Chen, J. Hu, L.-D. Guo, W. Zhong, C. Ning, J. Xu, Angew. Chem. Int. Ed. 2019, 58, 7390–7394.

Enantioselective Total Syntheses of Pallambins A-D

X. Zhang, X. Cai, B. Huang, L. Guo, Z. Gao, Y. Jia, Angew. Chem. Int. Ed. 2019, DOI: 10.1002/anie.201907523.

Total Synthesis of (+)-Daphmanidin E

M. E. Weiss, E. M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 11501–11505.

Total Synthesis of the Sesquiterpenoid Periconianone A Based on a Postulated Biogenesis

R. Liffert, A. Linden, K. Gademann, J. Am. Chem. Soc. 2017, 139, 16096–16099

Isolation, synthesis and bioactivity studies of phomactin terpenoids

Y. Kuroda, K. J. Nicacio, I. A. da Silva-Jr, P. R. Leger, S. Chang, J. R. Gubiani, V. M. Deflon, N. Nagashima, A. Rode, K. Blackford, A. G. Ferreira, L. D. Sette, D. E. Williams, R. J. Andersen, S. Jancar, R. G. S. Berlinck, R. Sarpong, Nature Chemistry 2018, 10, 938–945.

Convergent, Enantioselective Synthesis of (+)-Guanacastepene E

W. D. Shipe, E. J. Sorensen, J. Am. Chem. Soc. 2006, 128, 7025–7035.

Total Synthesis of (–)-Vindorosine

W. Chen, X.-D. Yang, W.-Y. Tan, X.-Y. Zhang, X.-L. Liao, H. Zhang, Angew. Chem. Int. Ed. 2017, 56, 12327–12331.

Total Syntheses of Rhodomolleins XX and XXII

K.Yu, Z.-N. Yang, C.-H. Liu, S.-Q. Wu, X. Hong, X.-L. Zhao, H. Ding, Angew. Chem. Int. Ed. 2019, 58, 8556–8560.

Enantioselective Total Synthesis of (+)-Flavisiamine F via Late-Stage
Visible-Light-Induced Photochemical Cyclization

X. Tong, B . Shi , K . Liang, Q. Liu , C . Xia, Angew. Chem. Int. Ed. 2019, 58, 5443–5446.

Total Synthesis of 1-Hydroxytaxinine

Y. Imamura, S. Yoshioka, M. Nagatomo, M. Inoue, Angew. Chem. Int. Ed. 2019. DOI: 10.1002/anie.201906872

Total Synthesis Cyclopiamine B

E. V. Mercado-Marin, P. Garcia-Reynaga, S. Romminger, E. F. Pimenta, D. K. Romney, M. W. Lodewyk, D. E. Williams, R. J. Andersen, S. J. Miller, D. J. Tantillo, R. G. S. Berlinck, R. Sarpong,
Nature 2014, 509, 318–324.

Chemoenzymatic Total Synthesis of ent-Oxycodone: Fourth generation

M. Makarova, M. A. A. Endoma-Arias, H. E. Dela Paz, R. Simionescu, T. Hudlicky, J. Am. Chem. Soc. 2019. DOI: 10.1021/jacs.9b05033

Total Synthesis of Arcutinine

W. Nie, J. Gong, Z. Chen, J. Liu, D. Tian, H.Song, X.-Y. Liu, Y. Qin, J. Am. Chem. Soc. 2019, 141, 9712.

Total Synthesis of (±)-Maoecrystal V

J. Gong, G. Lin, W. Sun, C.-C. Li, Z. Yang, J. Am. Chem. Soc. 2010, 132, 16745–16745.

Divergent Total Synthesis of Indoxamycins A, C, and F

C. He, C. Zhu, Z. Dai, C. Tseng, H. Ding, Angew. Chem. Int. Ed. 2013, 52, 13256–13260.

Quaternary-Center-Guided Synthesis of Complex Polycyclic Terpenes

P. Hu, H. Chi, K. C. DeBacker, X. Gong, J. H. Keim, I. Hsu, S. A. Snyder, S. A., Nature 2019, 569, 703.

Total Synthesis of (–)-Mitrephorone A

M. J. R. Richter, M. Schneider, M. Brandstatter, S. Krautwald, E. M. Carreira, J. Am. Chem. Soc. 2018, 140, 16704–16710.

Total Synthesis of (+)-Granatumine A and Related Bislactone Limonoid Alkaloids via a Pyran to Pyridine Interconversion

A. Schuppe, Y. Zhao, Y. Liu, T. Newhouse, J. Am. Chem. Soc. 2019. DOI: 10.1021/jacs.9b04508

Total Synthesis of the Glycosylated Macrolide Antibiotic Fidaxomicin

H. Miyatake-Ondozabal, E. Kaufmann, K. Gademann, Angew. Chem. Int. Ed. 2015, 54, 1933–1936.

Total Synthesis of (+)-Arborisidine

Z. Zhou, A. X. Gao, S. A. Snyder, J. Am. Chem. Soc. 2019, 141, 7715–7720.

Total Synthesis of (±)-Bukittinggine

J. A. Stafford, C. H. Heathcock, D. L. Clark, J. Org. Chem. 1992, 57, 2575–2585.

Asymmetric Total Synthesis of Cerorubenic Acid-III

X. Liu, J. Liu, J. Wu, G. Huang, R. Liang, L. W. Chung, C.-C. Li, J. Am. Chem. Soc. 2019, 141,  2872–2877.

The Enantioselective Total Synthesis of Exochomine

A. X. Gao, T. Hamada, S. A. Snyder, Angew. Chem. Int. Ed. 2016, 55, 10301–10306.

Scalable Total Synthesis of (–)-Vinigrol

X. Yu, L. Xiao, Z. Wang, T. Luo, J. Am. Chem. Soc. 2019, 141, 3440–3443.

Total Synthesis of (–)-Ambiguine P Using Sequential Indole Fuctionalizations

R. E. Johnson, H. Ree, M. Hartmann, L. Lang, S. Sawano, R. Sarpong, J. Am. Chem. Soc. 2019, 141, 2233–2237.

Total Syntheses of Bisdehydroneostemoninine and Bisdehydrostemoninine

K. Ma, X. Yin, M.Dai, Angew. Chem. Int. Ed. 2018, 57, 15209–15212.

Total synthesis of solanoeclepin A

K. Tanino, M. Takahashi, Y. Tomata, H. Tokura, T. Uehara, T. Narabu, M. Miyashita, Nat. Chem. 2011, 3, 484–488.

Total Synthesis of Epicolactone

A. G. Kravina, E. M. Carreira, Angew. Chem. Int. Ed. 2018, 57, 13159–13162.

Asymmetric synthesis of batrachotoxin: Enantiomeric toxins show functional divergence against NaV

M. M. Logan, T. Toma, R. Thomas-Tran, J. Du Bois, Science 2016, 354, 865–869.

Total Synthesis of (–)-Isoschizoagamine

Y. Miura, N. Hayashi, S. Yokoshima, T. Fukuyama, J. Am. Chem. Soc. 2012, 134, 11995.

A Scalable Total Synthesis of the Antitumor Agents Et-743 and Lurbinectedin

W. He, Z. Zhang, D. Ma, Angew. Chem. Int. Ed. 2019, 58, 1–5.

Total Synthesis of Astellatol

N. Zhao, S.Yin, S. Xie, H. Yan, P. Ren, G Chen, F. Chen, J. Xu, Angew. Chem. Int. Ed. 2018, 57, 3386.

Total Synthesis of Aplysiasecosterol A

Z. Lu, X. Zhang, Z. Guo, Y. Chen, T. Mu, A. Li, J. Am. Chem. Soc. 2018, 140, 9211–9218.

Total Syntheses of Various Amphilectane and Serrulatane Diterpenoids

X. Yu, F. Su, C. Liu, H. Yuan, S. Zhao, Z. Zhou, T. Quan, T. Luo, J. Am. Chem. Soc. 2016, 138, 6261.

Total Synthesis of (–)-Nahuoic Acid Ci (Bii)

Q. Liu, Y. Deng, A. B. Smith III, J. Am. Chem. Soc. 2017, 139, 13668–13671.

Total Syntheses of Highly Oxidized ent-Kaurenoid Pharicin A, Pharicinin B, 7-O-Acetylpseurata C, and Pseurata C: A [5+2] Cascade Approach

C. He, J. Hu, Y. Wu, H. Ding, J. Am. Chem. Soc. 2017, 139, 6098–6101.

Formal Total Synthesis of (+)-Pleuromutilin

E. P. Farney, S. S. Feng, F. Schäfers, S. E. Reisman, J. Am. Chem. Soc. 2018, 140, 1267–1270.

Total Synthesis of Isodihydrokoumine

J. K. Kerkovius, M. A. Kerr, J. Am. Chem. Soc. 2018, 140, 8415.

A Benzyne-Insertion Approach to Hetisine-Type Diterpenoid Alkaloids:
Synthesis of Cossonidine (Davisine)

K. G. M. Kou, J. J. Pflueger, T. Kiho, L. C. Morrill, E. L. Fisher, K. Clagg, T. P. Lebold, J. K. Kisunzu, R. Sarpong, J. Am. Chem. Soc. 2018, 140, 8105.

Intramolecular Photocycloaddtion-Cyclobutane Fragmentation: Total Synthesis of (±)-Silphinene

M.T. Crimmins, S. W. Mascarella, J. Am. Chem. Soc. 1986, 108, 3435–3438.

Total Synthesis of (–)-Histrionicotoxin and (–)-Histrionicotoxin 235A

G. Stork, K. Zhao, J. Am. Chem. Soc. 1990, 112, 5875.

Total Synthesis of (±)-Nakafuran-8

T. Uyehara, M. Sugimoto, I. Suzuki, Y. Yamamoto,  J. Chem. Soc. Chem. Commun. 1989, 1841–1842.

Total Synthesis of (–)-Chromodorolide B

D. J. Tao, Y. Slutskyy, M. Muuronen, A. Le, P. Kohler, L. E. Overman,  J. Am. Chem. Soc. 2018, 140, 3091–3102.

Bioinspired Total Synthesis of Sespenine

Y. Sun, P. Chen, D. Zhang, M. Baunach, C. Hertweck, A. Li, Angew. Chem. Int. Ed. 2014, 53, 9012–9016.

Enantioselective Total Synthesis of (+) and (–)-Nigellamine A2

J. Bian, M. van Wingerden, J. M. Ready, J. Am. Chem. Soc. 2006, 128, 7428–7429.

A Diosphenol-Based Strategy for the Total Synthesis of (–)-Terpestacin

B. M. Trost, G. Dong, J. A. Vance, J. Am. Chem. Soc. 2005, 129, 4541.

A Concise, Efficient and Scalable Total Synthesis of Thapsigargin and Nortilobide

D. Chen, P. A. Evans, J. Am. Chem. Soc. 2017, 139, 6046–6049.

Enantioselective Total Synthesis of (–)-Pavidolide B

P.-P. Zhang, Z.-M. Yang, J.-X.Gong, Z. Yang, J. Am. Chem. Soc. 2017, 139, 13989–13992.

Synthesis of (–)-11-O-Debenzoyltashironin: Neurotropic Sesquiterpenes cause Hyperexcitation

M. Ohtawa, M. J. Krambis, R. Cerne, J. M. Schkeryantz, J.M. Witkin, R. A. Shenvi, J. Am. Chem. Soc. 2017, 139, 9637–9644.

Synthesis and Structure Revision of Dichrocephones A and B

V. M. Schmiedel, Y. J. Hong, D. Lentz, D. J. Tantillo, M. Christmann, Angew. Chem. Int. Ed. 2018, 57, 2419–2422.

Synthesis of (±)-Merrilactone A by Desymmetrization Strategy

W. Liu, B. Wang, Chem. Eur. J. 2018. DOI: 10.1002/chem.201804195.

Total synthesis of natural (–)-echinosporin. Determination of the absolute configuration

A. B. Smith III, G. A. Sulikowski, K. Fujimoto, J. Am. Chem. Soc. 1989, 111, 8039–8041.

Total Synthesis of (±)-Aspergilline A

M. C. Nakhla, J. L. Wood, J. Am. Chem. Soc. 2017, 139, 18504–18507.

Asymmetric Total Syntheses of Colchicine, b-Lumicolchicine, and Allocolchicinoid N-Acetylcolchinol-O-methyl Ether (NCME)

B.Chen, X. Liu, Y. J. Hu, D.-M. Zhang, L. Deng, J. Lu, L. Min, W.-C. Ye, C.-C. Li, Chem. Sci. 2017, 8, 4961–4966.

X. Liu, Y.-J. Hu, B. Chen, L- Min, X.-S. Peng, J. Zhao, S. Li, H.N.C. Wong, C.-C. Li, Org. Lett. 2017,19, 4612–4615.

A Cascade Strategy Enables aTotal Synthesis of (±)-Morphine

S. Chu, N. Münster, T. Balan, M. D. Smith, Angew. Chem. Int. Ed. 2016, 55, 14306.

Total Synthesis of (–)-Dendrobine

C.-K. Sha, R.-T. Chiu, C.-F. Yang, N.-T. Yao, W.-H. Tseng, F.-L. Liao, S.-L. Wang, J. Am. Chem. Soc. 1997, 119, 4130–4135.

Total Synthesis of Cycloinumakiol

T. Xu, G. Dong, Angew. Chem. Int. Ed. 2014, 53, 10733–10736.

Total Synthesis of Actinophyllic Acid

Y. Yoshii, H. Tokuyama, D. Y.-K. Chen, Angew. Chem. Int. Ed. 2017, 56, 12277–12281.

Total Synthesis of Unsymmetrically Oxidized Nuphar Thioalkaloids via Copper-Catalyzed Thiolane Assembly

J. J. Lacharity, J. Fournier, P. Lu, A. K. Mailyan, A. T. Herrmann, A. Zakarian, J. Am. Chem. Soc. 2017, 139, 13272–13275.

Total Synthesis of Septedine

S. Zhou, R. Guo, P. Yang, Ang Li, J. Am. Chem. Soc. 2018, ASAP. DOI: 10.1021/jacs.8b03712.

Total Synthesis of Pyrroloazocine Indole Alkaloid Grandilodine C

F. M. Miloserdov, M. S. Kirillova, M. E. Muratore, A. M. Echavarren, J. Am. Chem. Soc. 2018, 140, 5393.

Unified Total Synthesis of Madangamines A, C, and E

T. Suto, Y. Yanagita, Y. Nagashima, S. Takikawa, Y. Kurosu, N. Matsuo, T. Sato, N. Chida, J. Am. Chem. Soc. 2017, 139, 2952.

Total Synthesis of (+)-Complanadine A Using an Iridium-Catalyzed Pyridine C-H Functionalization

D. F. Fischer, R. Sarpong, J. Am. Chem. Soc. 2010, 132, 5926–5927.

A Concise Total Synthesis of Salinketal B

J. Liu, J. K. De Brabander, J. Am. Chem. Soc. 2009, 131, 12562.

Studies on Total Synthesis of the Cytotoxic Marine Alkaloid Agelastatin A

G. T. Anderson, C. E. Chase, Y.-H. Koh, D. Stien, S. M. Weinreb, J. Org. Chem. 1998, 63, 7594.

Total Synthesis of (±)-Myrocin C

M. Y. Chu-Moyer, S. J. Danishefsky, G. K. Shulte, J. Am. Chem. Soc. 1994, 116, 11213–11228.

Total Syntheses of (+)- and (–)-Tetrapetalones A and C

H. H. Dhanjee, Y. Kobayashi, J. F. Buergler, T. C. McMahon, M.W. Haley, J, M. Howell, K. Fujiwara, J. L. Wood, J. Am. Chem. Soc. 2017, 139, 14901–14904.

Enantioselective Total Synthesis of Mandelalide A and Isomandelalide A: Discovery of a Cytotoxic Ring-Expanded Isomer

N. Veerasamy, A. Ghosh, J. Li, K. Watanabe, J. D. Serrill, J. E. Ishmael, K. L. McPhail, R. G. Carter, J. Am. Chem. Soc. 2016, 138, 770.

A General Strategy to Elisabethane Diterpoenes: Stereocontrolled Synthesis of Elisapterosin B via Oxidative Cyclization of an Elizabethin Precursor

N. Waizumi, A. R. Stankovic, V. H. Rawal, J. Am. Chem. Soc. 2003, 125, 13022–13023.

A modular and enantioselective synthesis of the pleuromutilin antibiotics

S. K. Murphy, M. Zeng, S. B. Herzon, Science 2017, 356, 956–959.

alpha-Ketenyl Radical Intermediates in the Synthesis of Propellanes. A Formal Synthesis of Modhephene

B. De Boeck, G. Pattenden, Tet. Lett. 1988, 39, 6975–6978.

A Synthesis of Alsmaphorazine B Demonstrates the Chemical Feasibility of a New Biogenetic Hypothesis

A. Y. Hong, C. D. Vanderwal, J. Am. Chem. Soc. 2015, 137, 7306–7309.

Total Syntheses of Scaparvins B, C, and D Enabled by a Key C-H Functionalization

Q.Ye, P. Qu, S. A. Snyder, J. Am. Chem. Soc. 2017, 139, 18428–18431.

Total Syntheses of (–)-Majucin and (–)-Jiadifenoxolane A, Complex Majucin-Type Illicium Sesquiterpenes

M. L. Condakes, K. Hung, S. J. Harwood, Thomas J. Maimone, J. Am. Chem. Soc. 2017, 139, 17783–17786.

Stereocontrolled total synthesis of (+)-paraherquamide B

T. D. Cushing, J. F. Sanz-Cervera, R. M. Williams, J. Am. Chem. Soc. 1993, 115, 9323–9332.

Development, Mechanistic Elucidation, and Rational Optimization of a Tandem Ireland
Claisen/Cope Rearrangement Reaction for Rapid Access to the (Iso)Cyclocitrinol Core

C. W. Plummer, C. S. Wei, C. E. Yozwiak, A. Soheili, S. O. Smithback, J. L. Leighton, J. Am. Chem.
Soc. 2014, 136, 9878–9881.

Total Synthesis of (–)-Xylogranatopyridine B via Palladium-Catalyzed Oxidative Stannlyation of Enones

A.W. Schuppe, D. Huang, Y. Chen, T. R. Newhouse, J. Am. Chem. Soc. 2018, 140, 2062–2066.

Synthesis of Strophasterol A Guided by a Proposed Biosynthesis and Innate Reactivity

R. C. Heinze, D. Lentz, P. Heretsch, Angew. Chem. Int. Ed. 2016, 55, 11656–11659.

Total Synthesis of (−)-Himalensine A

H. Shi, I. N. Michaelides, B. Darses, P. Jakubec, Q. N. N. Nguyen, R. S. Paton, D. J. Dixon, J. Am. Chem. Soc. 2017, 139, 17755–17758.

Total Synthesis of (+)-Chinensiolide B

T. G. Elford, D. G. Hall, J. Am. Chem. Soc. 2010, 132, 1488–1489.

Gram-Scale Enantioselective Formal Synthesis of Morphine

M. Tissot, R. J. Phipps, C. Lucas, R. M. Leon, R. D. M. Pace, T. Ngouansavanh, M. J. Gaunt
Angew. Chem. Int. Ed. 2014, 53, 13498–13501.

Total Synthesis of Phomoidride D

J. C. Leung, A. A. Bedermann, J. T. Njardarson, D. A. Spiegel, G. K. Murphy, N. Hama, B. M. Twenter, P. Dong, T. Shirahata, I. M. McDonald, M. Inoue, N. Taniguchi, T. C. McMahon, C. M. Schneider, N. Tao, B. M. Stoltz, J. L. Wood, Angew. Chem. Int. Ed. 2018, 57, 1991–1994.

Short, Enantioselective Total Synthesis of (+)-Chatancin

Y.-M. Zhao, T. J. Maimone, Angew. Chem. Int. Ed. 2015, 54, 1223–1226.

A 11-Steps Total Synthesis of Magellanine through a Gold(I)-Catalyzed Dehydro Diels-Alder Reaction

P. McGee, G. Bétournay, F. Barabé, L. Barriault, Angew. Chem. Int. Ed. 2017, 56, 6280–6283.

Total Syntheses of Dalesconol A and B

S. Snyder, T. Sherwood, A. Ross, Angew. Chem. Int. Ed. 2010, 49, 5146–5150.

Total Synthesis of 4-Desmethyl-3alpha-hydroxy-15-rippertene

R. Henning, P. Metz, Angew. Chem. Int. Ed. 2009, 48, 1157–1159.

Enantioselective Total Syntheses of Akuammiline Alkaloids (+)-Strictamine, (−)-2(S)-Cathafoline, and (−)-Aspidophylline A

J. Moreno, E. Picazo, L. A. Morrill, J. M. Smith, N. K. Garg, J. Am. Chem. Soc. 2016, 138, 1162–1165.

Total Synthesis of Longeracinphyllin A

J. Li, W. Zhang, F. Zhang, Y. Chen, A. Li, J. Am. Chem. Soc. 2017, 139, 14893–14896.

Total Synthesis of (−)-Mandelalide A Exploiting Anion Relay Chemistry (ARC)

M. H. Nguyen, M. Imanishi, T. Kurogi, and A. B. Smith, III,  J. Am. Chem. Soc. 2016, 138, 3675.

Synthesis of the Paralytic Shellfish Poisons (+)-Gonyautoxin 2, (+)-Gonyautoxin 3 and (+)-11,11-Dihydroxysaxitoxin

J. V. Mulcahy, J. R. Walker, J. E. Merit, A. Whitehead, J. Du Bois, J. Am. Chem. Soc. 2016, 138, 5994−6001.

Total Synthesis of (+)-Pleuromutilin

N. J. Fazakerley, M. D. Helm, D. J. Procter, Chem. Eur. J. 2013, 19, 6718–6723.

Asymmetric Total Synthesis of ent-(−)-Roseophilin: Assignment of Absolute Configuration

D. L. Boger, J. Hong, J. Am. Chem. Soc. 2001, 123, 8515–8519.

An Efficient Synthetic Approach to Cyanocycline A via [C+NC+CC] Coupling

Ü. Kaniskan, P. Garner, J. Am. Chem. Soc. 2007, 129, 15460–15461.

Asymmetric Total Synthesis of Solandelactone E

A. Robinson, V. K. Aggarwal, Angew. Chem. Int. Ed. 2010, 49, 6673–6675.

Total Synthesis of the Protein Phosphatase 2A Inhibitor Lactodehydrothyrsiferol

D. J. Clausen, S. Wan, P. E. Floreancing, Angew. Chem. Int. Ed. 2011, 50, 5178–5181.

Enantioselective Total Synthesis of (+)-Psiguadial B

L. M. Chapman, J. C. Beck, L. Wu, S. E. Reisman, J. Am. Chem. Soc. 2016, 138, 9803–9806.

Asymmetric Total Syntheses of Kopsia Indole Alkaloids

L. Leng, X. Zhou, Q. Liao, F. Wang, H. Song, D. Zhang, X. Liu, Y. Qin, Angew. Chem. Int. Ed. 2017, 56, 3703–3707.

A Biomimetic Synthesis of (±)-Basiliolide B

X. Liang, L. Zhou, L. Min, W. Ye, W. Bao, W. Ma, Q. Yang, F. Qiao, X. Zhang, C.-S. Lee, Angew. Chem. Int. Ed. 2014, 53, 11294–11297.

A Carbene Catalysis Strategy for the Synthesis of Protoilludane Natural Products: Total Synthesis of Armillaridin and Isovelleral

M. T. Hovey, D. T. Cohen, D. M. Walden, P. H.-Y. Cheong, K. A. Scheidt, Angew. Chem. Int. Ed. 2017, 56, 9864–9867.

Total Synthesis of (−)-Dactylolide

S. Y. Yun, E. C. Hansen, I. Volchkov, E. J. Cho, W. Y. Lo, D. Lee, Angew. Chem. Int. Ed. 2010, 49, 4261–4263.

Total Synthesis of (±)-spiramilactone B

H. Cheng, F.-H. Zeng, X. Yang, Y.-J. Meng, L. Xu, F.-P. Wang, Angew. Chem. Int. Ed. 2016, 55, 392–396.

Biomimetic Total Synthesis of the Pentacyclic Amaryllidaceae Alkaloid Derivative Gracilamine

N. Y. Gao, M. G. Banwell, A. C. Willis, Org. Lett. 2017, 19, 162–165.

Total Syntheses of Highly Oxidized ent-Kaurenoids Pharicin A, Pharicinin B, 7-O-Acetylpseurata C, and Pseurata C: A [5+2] Cascade Approach

C. He, J. Hu, Y. Wu, H. Ding, J. Am. Chem. Soc. 2017,139, 6098.

Total synthesis of securinega alkaloids (−)-norsecurinine, (−)-niruroidine and (−)-flueggine A

N. Ma, Y. Yao, B.-X. Zhao, Y. Wang, W.-C. Ye, S. Jiang, Chem. Commun. 2014, 50, 9284–9287.

Total Synthesis of (−)-Nakadomarin A

M. G. Nilson, R. L. Funk, Org. Lett. 2010, 12, 4912–4915.

Total Synthesis of (−)-Histrionicotoxin through a Stereoselective Radical Translocation-Cyclization Reaction

M. Sato, H. Azuma, A. Daigaku, S. Sato, K. Takasu, K. Okano, H. Tokuyama, Angew. Chem. Int. Ed. 2017, 56, 1087–1091.

A concise synthesis of (+)-batzelladine B from simple pyrrole-based starting materials