Applied Methods and Devices
Methods
Analytical
- High-performance liquid chromatography
- Gas chromatography
- Ion chromatography
- FIA (HPLC: OPA-NAC)
- (Fluorescence) Spectrophotometry
Molecular biological
- qPCR and digital PCR (dPCR)
- 16S rRNA sequencing including library preparations and bioinformatic analyses
- Whole genome sequencing including bioinformatic analyses
- Nanopore long-read sequencing
Microbiological
- aerobic and anaerobic cultivation
- semi-continuous anaerobic digestion
- batch AD
- handling of anaerobic pure and co cultures
- culture separation under anaerobic conditions
Devices
Analytical
- Shimadzu GC-2010 gaschromatograph (Shimadzu, Japan) with FI and TC detectors
- Shimadzu Prominence HPLC Systems (modular) with UV-Vis-, Refractive Index (RI)-, Fluorescence (RF-20Axs)- and Photodiode Array detectors (SPD), and pumps for post-column derivatisation (Shimadzu, Japan)
- Hitachi U2001 UV-VIS Spectrophotometer (Hitachi, Japan)
- Ion Chromatography Systems (Metrohm, Switzerland)
- Hitachi F-4500 fluorescence spectrophotometer (Hitachi, Japan)
- FTIR-8201PC Spectrophotometer (Shimadzu, Japan)
Molecular biological
- qPCR device Rotor-Gene Q (Qiagen, Denmark)
- digitalPCR System QIAcuity One, 5plex (Qiagen, Denmark)
- QIAxcel instrument for capillary electrophoresis (Qiagen, Denmark)
- Biomek liquid handler (Coulter Beckman, USA) with various equipment for automatic pipetting and dilutions, extraction, NGS library preparation, application of magnetic beads etc.
- Fast-Prep 24 (MP Biomedicals, USA) for cell-disruption (bead beating) during DNA/RNA extraction
- Nanopore MinION long-sequencing device (Oxford Nanopore Technologies, UK)
Microbiological
- Climatic chambers and anaerobic jars
- Glove boxes for working under oxygen-free conditions
- Automatic gas exchanger and pressure filling device (GR-Instruments, Netherlands) for preparing anoxic media
- Various Widdle-flasks
- Gas-tight batch reactors
- 0.5 – 12 L bioreactors (Sartorius or self-made): automatic temperature control, automatic dosing/feeding/deduction system (time-controlled multi-channel pump), on-line biogas counting (AMPTS), stirring system
- AMPTS II Automatic Methane Potential Test System (BPC Instruments, Sweden)
- Research microscope including fluorescence equipment (NIKON eclipse) with high resolution imaging option and evaluation software