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Sargazifar, Z., Esmaeilzadeh Kashi, M., Tazik, Z., Mottaghipisheh, J., Hosseini, S. H., Stuppner, H., Abolfazl, S., Asili, J. (2022). A new diterpenoid from Salvia santolinifolia boiss. Nat. Prod. Res., 38(9), 1570–1576. https://doi.org/10.1080/14786419.2022.2161538 (Impact Factor, 2.2)
2023
Rojsanga, P.; Schwaiger, S.; Stuppner, H.; Sithisarn, P. Determination of Phytochemical Contents in Extracts from Different Growth Stages of Oroxylum indicum Fruits Using HPLC-DAD and QAMS Methods. Molecules 2023, 28, 6837. https://doi.org/10.3390/molecules28196837 (Impact Factor, 4.2)
Horgan, M., Zell, L., Siewert, B., Stuppner, H., Schuster, D., Temml, V. Identification of Novel β-Tubulin Inhibitors Using a Combined In Silico/In Vitro Approach. J. Chem. Inf. Model.2023, 63, 20, 6396–6411, https://doi.org/10.1021/acs.jcim.3c00939 (Impact Factor, 4.2)
Saquib, Q.; Schwaiger, S.; Alilou, M.; Ahmed, S.; Siddiqui, M.A.; Ahmad, J.; Faisal, M.; Abdel-Salam, E.M.; Wahab, R.; Al-Rehaily, A.J., Stuppner, H., Al-Khedhairy, A. A. Marine Natural Compound (Neviotin A) Displays Anticancer Efficacy by Triggering Transcriptomic Alterations and Cell Death in MCF-7 Cells. Molecules 2023, 28, 6289. https://doi.org/10.3390/molecules28176289 (Impact Factor, 4.2)
Braun, V.; Stuppner, H.; Seger, C. Non-Steroidal Drug Interferences in a Quantitative Multisteroid LC-MS/MS Assay. Cells 2023, 12, 329. https://doi.org/10.3390/cells12020329 (Impact Factor, 4.2)
Villicaña González, E., Schwaiger, S., Stuppner, H. Two-step isolation of the two major paraconic acids of Cetraria islandica, J. Sep. Sci. 2023, 46(6), 2200805. https://doi.org/10.1002/jssc.202200805 (Impact Factor, 3.1)
Koeberle, S. C., Kipp, A. P., Stuppner, H., Koeberle, A. Ferroptosis-modulating small molecules for targeting drug-resistant cancer: Challenges and opportunities in manipulating redox signaling. Med. Res. Rev. (2023), 43(3), 614-682. https://doi.org/10.1002/med.21933 (Impact Factor, 13.3)
Pecio, Ł., Alilou, M., Kozachok, S., Orhan, I.E., Eren, G., Şenol Deniz, F.S., Stuppner, H., Oleszek, W. Absolute configuration of spiro-flavostilbenoids from Yucca schidigera Roezl ex Ortgies: First indication of (2R)-naringenin as the key building block. Phytochemistry, 207, 2023, 113584. https://doi.org/10.1016/j.phytochem.2022.113584 (Impact Factor, 3.2)
Martinidou,E., Palmieri, L., Sordo, M., Masuero, D., Ourda, M., Delucchi, L., Fusani, P., Tremml, V., Poulopoulou, I., Gauly, M., Horgan, M. J., Siewert, B., Stuppner, H., Martens, S. Assessment of the chemical and genetic variability among accessions of Cicerbita alpina (L.) Wallr., an alpine plant with anthelmintic properties. Front. Plant Sci., 2023, 14. https://doi.org/10.3389/fpls.2023.1269613 (Impact Factor, 5.6)
Poulopoulou, I., Horgan, M.J., Siewert, B., Siller, M., Palmieri, L., Martinidou, E., Martens, S., Fusani, P., Temml, V., Stuppner, H., Gauly, M. In vitro evaluation of the effects of methanolic plant extracts on the embryonation rate of Ascaridia galli eggs. Vet. Res. Commun. 47, 409–419 (2023). https://doi.org/10.1007/s11259-022-09958-9 (Impact Factor, 1.8)
2022
Braun V, Stuppner H, Risch L, Seger C. Design and Validation of a Sensitive Multisteroid LC-MS/MS Assay for the Routine Clinical Use: One-Step Sample Preparation with Phospholipid Removal and Comparison to Immunoassays. Int J Mol Sci. 2022 Nov 24;23(23):14691. doi: 10.3390/ijms232314691. PMID: 36499017; PMCID: PMC9736865.
Nguyen-Ngoc H, Alilou M, Derbré S, Blanchard P, Pham GN, Nghiem DT, Richomme P, Stuppner H, Ganzera M. Chemical constituents of Antidesma bunius aerial parts and the anti-AGEs activity of selected compounds. Phytochemistry. 2022 Oct;202:113300. doi: 10.1016/j.phytochem.2022.113300. Epub 2022 Jul 5. PMID: 35798090.
Mittas D, Mawunu M, Magliocca G, Lautenschläger T, Schwaiger S, Stuppner H, Marzocco S. Bioassay-Guided Isolation of Anti-Inflammatory Constituents of the Subaerial Parts of Cyperus articulatus (Cyperaceae). Molecules. 2022 Sep 13;27(18):5937. doi: 10.3390/molecules27185937. PMID: 36144672; PMCID: PMC9504922.
Mittas D, Spitaler U, Bertagnoll M, Oettl S, Gille E, Schwaiger S, Stuppner H. Identification and structural elucidation of bioactive compounds from Scirpoides holoschoenus. Phytochemistry. 2022 Aug;200:113241. doi: 10.1016/j.phytochem.2022.113241. Epub 2022 May 18. PMID: 35597313.
Gibitz-Eisath N, Seger C, Schwaiger S, Sturm S, Stuppner H. Simultaneous Quantitative Analysis of the Major Bioactive Compounds in Gentianae Radix and its Beverages by UHPSFC-DAD. J Agric Food Chem.2022 Jun 22;70(24):7586-7593. doi: 10.1021/acs.jafc.2c01584. Epub 2022 Jun 13. PMID: 35695390; PMCID: PMC9228070.
Poulopoulou I, Horgan MJ, Siewert B, Siller M, Palmieri L, Martinidou E, Martens S, Fusani P, Temml V, Stuppner H, Gauly M. In vitro evaluation of the effects of methanolic plant extracts on the embryonation rate of Ascaridia galli eggs. Vet Res Commun. 2022 Jun 21. doi: 10.1007/s11259-022-09958-9. Epub ahead of print. PMID: 35727416.
Enayati A, Salehi A, Alilou M, Stuppner H, Mirzaei H, Omraninava A, Khori V, Yass N. Six new triterpenoids from the root of Potentilla reptans and their cardioprotective effects in silico. Natural Product Research, 2022, online first, doi: 10.1080/14786419.2021.1912043. Epub 2021 Apr 19. PMID: 33866888.
Mirzania F, Moridi Farimani M, Sarrafi Y, Nejad Ebrahimi S, Troppmair J, Kwiatkowski M, Stuppner H, Alilou M. New Sesterterpenoids from Salvia mirzayanii Rech.f. and Esfand. Stereochemical Characterization by Computational Electronic Circular Dichroism. Front Chem. 2022 Jan 20;9:783292. doi: 10.3389/fchem.2021.783292. PMID: 35127644; PMCID: PMC8810545.
Ahmadi E, Rezadoost H, Alilou M, Stuppner H, Farimani MM. Purification, structural characterization and antioxidant activity of a new arabinogalactan from Dorema ammoniacum gum. International Journal of Biological Macromolecules, 2022, 194, 1019-1028 doi: 10.1016/j.ijbiomac.2021.11.163. Epub 2021 Nov 27. PMID: 34848241.
Pechlaner R, Friedrich N, Staudt A, Gande N, Bernar B, Stock K, Kiechl SJ, Hochmayr C, Griesmacher A, Petersmann A, Budde K, Stuppner H, Sturm S, Dörr M, Schminke U, Cannet C, Fang F, Schäfer H, Spraul M, Geiger R, Mayr M, Nauck M, Kiechl S, Kiechl-Kohlendorfer U, Knoflach M; Early Vascular Ageing (EVA) Study Group. Association of adolescent lipoprotein subclass profile with carotid intima-media thickness and comparison to adults: Prospective population-based cohort studies. Atherosclerosis. 2022 Jan;341:34-42. doi: 10.1016/j.atherosclerosis.2021.12.007. Epub 2021 Dec 16. PMID: 34995985.
Kretzer C, Jordan PM, Meyer K, Hoff D, Werner M, Hofstetter R, Koeberle A, Helesbeux J, Stuppner H, Temml V, Schuster D, Werz O. Natural chalcones elicit formation of specialized pro-resolving mediators and related 15-lipoxygenase products in human macrophages. Biochemical Pharmacology, 2022, 195, No. 114825. doi: 10.1016/j.bcp.2021.114825. Epub 2021 Nov. 8. PMID: 34762841.
Mayr S, Strasser S, Kirchler CG, Meischl F, Stuppner S, Beć KB, Grabska J, Sturm S, Stuppner H, Popp MA, Bonn GK, Huck CW. Quantification of Silymarin in Silybi mariani fructus: challenging the analytical performance of benchtop vs. handheld NIR spectrometers on whole seeds. Planta Medica, 2022, 88(1), 20-32. doi: 10.1055/a-1326-2497. Epub 2021 Jan 12. PMID: 33434938.
2021
Gratl V, Sturm S, Zini E, Letschka T, Stefanini M, Vezulli S, Stuppner H. Comprehensive polyphenolic profiling in promising resistant grapevine hybrids including 17 novel breeds in northern Italy. Journal of the Science of Food and Agriculture, 2021, 101(6), 2380-2388. doi: 10.1002/jsfa.10861
Gregoriou G, Neophytou C M, Vasincu A, Gregoriou Y, Hadjipakkou H, Pinakoulaki E, Christodoulou M C, Ioannou G D, Stavrou I J, Christou A, Kapnissi-Christodoulou C P, Stavrou I J, Aigner S, Stuppner H, Kakas A, Andreas I. C. Anti-Cancer Activity and Phenolic Content of Extracts Derived from Cypriot Carob (Ceratonia siliqua L.) Pods Using Different Solvents. Molecules, 2021, 26(16), 5017. doi: 10.3390/molecules26165017
Hafez Goran S, Firuzi O, Asadollahi M, Stuppner H, Alilou M, Jassbi AR. Dammarane-type triterpenoid saponins from Salvia russellii Benth. Phytochemistry, 2021, 184, 112653. doi: 10.1016/j.phytochem.2020.112653
Karimzadeh SM, Moridi F, Mahdi A, Mohammad S, Tabefam M, Alilou M, Stuppner H. Perovskanol, a new sesquiterpenoid with an unprecedented skeleton from Perovskia abrotanoides. Natural Product Research, 2021, 35(15), 2515-2519. doi: 10.1080/14786419.2019.1684280
Mikayoulou M, Mayr F, Temml V, Pandian A, Vermaak I, Chen W, Komane B, Stuppner H, iljoen A. Anti-tyrosinase activity of South African Aloe species and isolated compounds plicataloside and aloesin. Fitoterapia, 2021, 150, 104828. doi: 10.1016/j.fitote.2021.104828
Mottaghipisheh J, Stuppner H. A Comprehensive Review on Chemotaxonomic and Phytochemical Aspects of Homoisoflavonoids, as Rare Flavonoid Derivatives. International Journal of Molecular Sciences, 2021, 22(5), 2735. doi: 10.3390/ijms22052735
Neukirch K, Alsabil K, Dinh C-P, Bilancia R, Raasch M, Ville, A, Cerqua I, Viault G, Bréad D, Pace S, Temml V, Brunner E, Jordan P M, Marques M C, Loeser K, Gollowitzer A, Permann St, Gerstmeiner J, Lorkowski S, Stuppner H, Garscha U, Rodrigues T, Bernardes G J L, Schuster D, Séraphin D, Richomme P, Rossi A, Mosig A S, Roviezzo R, Werz O, Helesbeux J-J, Koeberle A. Exploration of Long-Chain Vitamin E Metabolites for the Discovery of a Highly Potent, Orally Effective, and Metabolically Stable 5-LOX Inhibitor that Limits Inflammation. Journal of Medicinal Chemistry, 2021, 64(15), 11496-11526. doi: 10.1021/acs.jmedchem.1c00806
Nguyen DTX, Tran H, Schwaiger S, Stuppner H, Marzocco S. Effect of Non‐Volatile Constituents of Elsholtzia ciliata (THUNB.) HYL. from Southern Vietnam on Reactive Oxygen Species and Nitric Oxide Release in Macrophages. Chemistry & Biodiversity, 2021, 18(1), e2000577. doi: 10.1002/cbdv.202000577
Rapa SF, Di Paola R, Cordaro M, Siracusa R, D´Amico R, Fusco R, Autore G, Cuzzocrea S, Stuppner H, Marzocco S. Plumericin Protects against Experimental Inflammatory Bowel Disease by Restoring Intestinal Barrier Function and Reducing Apoptosis. Biomedicines, 2021, 9(1), 67. doi: 10.3390/biomedicines9010067
Sturm S, Högner C, Seger C, Stuppner H. Combining HPLC-DAD-QTOF-MS and HPLC-SPE-NMR to Monitor In Vitro Vitetrifolin D Phase I and II Metabolism. Metabolites, 2021, 11(8), 529. doi: 10.3390/metabo11080529
Tran TVA, Alilou M, Zhigang R, Pace S, Schwaiger S, Kretzer C, Temml V, Giesel C, Jordan PM, Bilancia R, Weinigel C, Rummler S, Waltenberger B, Hung T, Rossi A, Stuppner H, Werz Oliver, Koeberle A. From Vietnamese plants to a biflavonoid that relieves inflammation by triggering the lipid mediator class switch to resolution. Acta Pharmaceutica Sinica B, 2021, 11(6), 1629-1647. doi: 10.1016/j.apsb.2021.04.011
2020
Alilou M, Marzocco S, Batooli H, Troppmair J, Schwaiger S, Stuppner H. Unusual secondary metabolites of the aerial parts of Dionysia diapensifolia Bioss. (Primulaceae) and their anti-inflammatory activity. Biomolecules, 2020, 10(3), 438. doi: 10.3390/biom10030438
Alilou M, Dibwe DF, Schwaiger S, Khomadi M, Troppmair J, Awale S, Stuppner H. Antiausterity Activity of Secondary Metabolites from the Roots of Ferula hezarlalehzarica against the PANC-1 Human Pancreatic Cancer Cell Line. Journal of Natural Products, 2020, 83(4), 1099-1106. doi: 10.1021/acs.jnatprod.9b01109
Alilou M, Marzocco S, Hofer D, Rapa SF, Asadpour R, Schwaiger S, Troppmair J, Stuppner H. Labdane-Type Diterpenes from the Aerial Parts of Rydingia persica: Their Absolute Configurations and Protective Effects on LPS-Induced Inflammation in Keratinocytes. Journal of Natural Products, 2021, 83(8), 2456-2468. doi: 10.1021/acs.jnatprod.0c00360
Dao-Huy T, Latkolik S, Bräuer J, Pfeil A, Stuppner H, Schnürch M, Dirsch VM, Mihovilovic MD. Structural Features Defining NF-κB Inhibition by Lignan-Inspired Benzofurans and Benzothiophenes. Biomolecules, 2021, 10(8), No. 1131. doi: 10.3390/biom10081131
Dinh CP, Ville A, Viault G, Richomme P, Seraphin D, Neukirch K, Koeberle A, Temml V, Stuppner H, Werz O, Schuster D, Helesbeux J-J. Structure-based design, semi-synthesis and anti-inflammatory activity of tocotrienolic amides as 5-lipoxygenase inhibitors. European Journal of Medicinal Chemistry, 2020, 202, 112518. doi: 10.1016/j.ejmech.2020.112518
Engels NS, Gierlikowska B, Waltenberger B, Chang Fr, Kiss AK, Stuppner H. A New Diterpene and Anti-inflammatory Sesquiterpene Lactones from Sigesbeckia orientalis. Planta Medica, 2021, 86(15), 1108-1117. doi: 10.1055/a-1232-6869
Gibitz-Eisath N, Eichberger M, Gruber R, Seger C, Sturm S, Stuppner H. Towards eco-friendly secondary plant metabolite quantitation: ultra-high performance supercritical fluid chromatography applied to common vervain (Verbena officinalis L.).Journal of Separation Science, 2020, 43(4), 829-838. doi: 10.1002/jssc.201900854
Jöhrer K, Stuppner H, Greil R, Cicek S.S. Structure-guided identification of black cohosh (Actaea racemosa) triterpenoids with in vitro activity against multiple myeloma. Molecules, 2020, 25(4), 766. doi: 10.3390/molecules25040766
Kafka M, Mayr F, Temml V, Möller G, Adamski J, Höfer J, Schwaiger S, Heidegger I, Matuszczak B, Schuster D, Klocker H, Bektic J, Stuppner H, Eder IE. Dual Inhibitory Action of a Novel AKR1C3 Inhibitor on Both Full-Length AR and the Variant AR-V7 in Enzalutamide Resistant Metastatic Castration Resistant Prostate Cancer. Cancers, 2020, 12(8), No. 2092. doi: 10.3390/cancers12082092
Karimzadeh SM, Moridi F, Mahdi A, Mohammad S, Tabefam M, Alilou M, Stuppner H. Perovskanol, a new sesquiterpenoid with an unprecedented skeleton from Perovskia abrotanoides. Natural Product Research, 2020, online first 2020, doi: 10.1080/14786419.2019.1684280
Linder T, Geyrhofer S, Papaplioura E, Wang L, Atanasov AG, Stuppner H, Dirsch VM, Schnürch M, Mihovilovic MD. Design and Synthesis of a Compound Library Exploiting 5-Methoxyleoligin as Potential Cholesterol Efflux Promoter. Molecules, 2020, 25(3), 662. doi: 10.3390/molecules25030662
Mayr F, Moller G, Garscha U, Fischer J, Castano PR, Inderbinen SG, Temml V, Waltenberger B, Schwaiger S, Hartmann RW, Gege C, Martens S, Odermatt A, Pandey AV, Werz O, Adamski J, Stuppner H, Schuster D. Finding New Molecular Targets of Familiar Natural Products Using In Silico Target Prediction. International Journal of Molecular Sciences,2020, 21(19), No. 7102. doi: 10.3390/ijms21197102
Moosmang S, Sturm S, Novak J, Lukas B, Stuppner H. Differentiation between Cistus L. (Sub-) Species (Cistaceae) Using NMR Metabolic Fingerprinting. Planta Medica, 2020, 86(15), 1148-1155. doi: 10.1055/a-1176-1937
Pompermaier L, Schwaiger S, Mawunu M, Lautenschlaeger T, Stuppner H, Faure K. Purification of thonningianins A and B and four further derivatives from Thonningia sanguinea by one‐ and two‐dimensional centrifugal partition chromatography. Journal of Separation Science, 2020, 43(2), 524-530. doi: 10.1002/jssc.201900811
Rapa SF, Waltenberger B, Di Paola R, Adesso S, Siracusa R, Peritore AF, D'Amico R, Autore G, Cuzzocrea S, Stuppner H, Marzocco S. Plumericin prevents intestinal inflammation and oxidative stress in vitro and in vivo. FASEB Journal, 2020, 34(1), 1576-1590. doi: 10.1096/fj.201902040R
Reider SJ, Moosmang S, Tragust J, Trgovec-Greif L, Tragust S, Perschy L, Przysiecki N, Sturm S, Tilg H, Stuppner H, Rattei T., Moschen AR. Prebiotic Effects of Partially Hydrolyzed Guar Gum on the Composition and Function of the Human Microbiota—Results from the PAGODA Trial. Nutrients, 2020, 12(5), 1257. doi: 10.3390/nu12051257
Soroury S, Alilou M, Gelbrich T, Tabefam M, Danton O, Ebrahimi SN, Kaiser M, Hamburger M, Stuppner H, Moridi Farimani M. Unusual derivatives from Hypericum scabrum. Scientific Reports, 2020, 10, 22181. doi: 10.1038/s41598-020-79305-y
2019
Braeuer P, Anielski P, Schwaiger S, Stuppner H, Tran TVA, Vollmer G, Zierau O, Thieme D, Keiler AM. In vitro metabolism of selected bioactive compounds of Eurycoma longifolia root extract to identify suitable markers in doping control. Drug Testing and Analysis, 2019, 11(1), 86-94. Doi: 10.1002/dta.2449
Danzl K, Messner B, Doppler C, Nebert C, Abfalterer A, Sakic A, Temml V, Heinz K, Streitwieser R, Edelmann T, Mairhofer M, Grimm M, Laufer G, Zierer A, Stuppner H, Schuster D, Ploner C, Müller T, Bernhard D. Early inhibition of endothelial retinoid uptake upon myocardial infarction restores cardiac function and prevents cell, tissue, and animal death.Journal of Molecular and Cellular Cardiology, 2019, 126, 105-117. Doi: 10.1016/j.yjmcc.2018.11.012
Engels NS, Waltenberger B., Schwaiger S, Huynh L, Tran H, Stuppner H. Melodamide A from Melodorum fruticosum - Quantification using HPLC and one-step-isolation by centrifugal partition chromatography. Journal of Separation Science,2019, 42, 3165-3172. Doi: 10.1002/jssc.201900392
Ferraz Gomes A, Almeida MP, Leite MF, Schwaiger S, Stuppner H, Halabalaki M, Amaral JG, David JM. Seasonal variation in the chemical composition of two chemotypes of Lippia alba. Food Chemistry, 2019, 273, 186-193. Doi: 10.1016/j.foodchem.2017.11.089
Gerstmeier J, Seegers J, Witt F, Waltenberger B, Temml V, Rollinger JM, Stuppner H, Koeberle A, Schuster D, Werz O. Ginkgolic acid is a multi-target inhibitor of key enzymes in pro-inflammatory lipid mediator biosynthesis. Frontiers in Pharmacology,2019, 10, No. 797. Doi: 10.3389/fphar.2019.00797
Linder T, Liu R, Atanasov AG, Li Y, Geyrhofer S, Schwaiger S, Stuppner H, Schnürch M, Dirsch VM, Mihovilovic MD. Leoligin-inspired synthetic lignans with selectivity for cell-type and bioactivity relevant for cardiovascular disease. Chemical Science, 2019, 10(22), 5815–5820. Doi: 10.1039/C9SC00446G
Mayr F, Sturm S, Ganzera M, Waltenberger B, Martens S, Schwaiger S, Stuppner H. Mushroom Tyrosinase-Based Enzyme Inhibition Assays Are Not Suitable for Bioactivity-Guided Fractionation of Extracts. Journal of Natural Products, 2019, 82(1), 136-147. Doi: 10.1021/acs.jnatprod.8b00847
McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, Crimmins MT, Csete M, Dewapriya P, Egan JM, Garson MJ, Genta-Jouve G, Gerwick WH, Gross H, Harper MK, Hermanto P, Hook JM, Hunter L, Jeannerat D, Ji NY, Johnson TA, Kingston DGI, Koshino H, Lee HW, Lewin G, Li J, Linington RG, Liu M, McPhail KL, Molinski TF, Moore BS, Nam JW, Neupane RP, Niemitz M, Nuzillard JM, Oberlies NH, Ocampos FMM, Pan G, Quinn RJ, Reddy DS, Renault JH, Rivera-Chávez J, Robien W, Saunders CM, Schmidt TJ, Seger C, Shen B, Steinbeck C, Stuppner H, Sturm S, Taglialatela-Scafati O, Tantillo DJ, Verpoorte R, Wang BG, Williams CM, Williams PG, Wist J, Yue JM, Zhang C, Xu Z, Simmler C, Lankin DC, Bisson J, Pauli GF. The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. Natural Product Reports, 2019, 36(1), 35-107. Doi: 10.1039/c7np00064b
Michalak B, Piwowarski JP, Granica S, Waltenberger B, Atanasov AG, Khan SY, Breuss JM, Uhrin P, Zyznska-Granica B, Stojakowska A, Stuppner H, Kiss AK. Eupatoriopicrin Inhibits Pro-inflammatory Functions of Neutrophils via Suppression of IL-8 and TNF-alpha Production and p38 and ERK 1/2 MAP Kinases. Journal of Natural Products, 2019, 82(2), 375-385. Doi: 10.1021/acs.jnatprod.8b00939
Moosmang S, Pitscheider M, Sturm S, Seger C, Tilg H, Halabalaki M, Stuppner H. Metabolomic analysis—Addressing NMR and LC-MS related problems in human feces sample preparation. Clinica Chimica Acta, 2019, 489, 169-176. Doi: 10.1016/j.cca.2017.10.029
Moosmang S, Siltari A, Bolzer MT, Kiechl S, Sturm S, Stuppner H. Development, validation, and application of a fast, simple, and robust SPE-based LC-MS/MS method for quantification of angiotensin I-converting enzyme inhibiting tripeptides Val-Pro-Pro, Ile-Pro-Pro, and Leu-Pro-Pro in yoghurt and other fermented dairy products. International Dairy Journal, 2019, 97, 31-39. Doi: 10.1016/j.idairyj.2019.05.005
Nguyen Ngoc H, Alilou M, Stonig M, Nghiem DT, Kim LT, Gostner JM, Stuppner H, Ganzera M. Terpenoids from the Stems of Fissistigma polyanthoides and Their Anti-Inflammatory Activity. Journal of Natural Products, 2019, 82(11), 2941-2952. Doi: 10.1021/acs.jnatprod.9b00208
Nguyen Ngoc H, Löffler S, Nghiem DT, Pham TLG, Stuppner H, Ganzera M. Phytochemical study of Rourea minor stems and the analysis of therein contained Bergenin and Catechin derivatives by capillary electrophoresis. Microchemical Journal, 2019, 149, No. 104063. Doi: 10.1016/j.microc.2019.104063
Nguyen Ngoc H, Mair L, Nghiem DT, Le Thien K, Gostner JM, Stuppner H. Ganzera M. Phenolic compounds from the stems of Fissistigma polyanthoides and their anti-oxidant activities. Fitoterapia, 2019, 137, No. 104252. Doi: 10.1016/j.fitote.2019.104252
Pecio L, Alilou M, Kozachok S, Erdogan Orhan I, Eren G, Deniz FSS, Stuppner H, Oleszek W. Yuccalechins A–C from the Yucca schidigera Roezl ex Ortgies Bark: Elucidation of the Relative and Absolute Configurations of Three New Spirobiflavonoids and Their Cholinesterase Inhibitory Activities. Molecules, 2019, 24/22, No. 4162. Doi: 10.3390/molecules24224162
Pompermaier L, Schwaiger S, Mawunu M, Lautenschläger T, Stuppner H. Development and Validation of a UHPLC-DAD Method for the Quantitative Analysis of Major Dihydrochalcone Glucosides from Thonningia sanguinea VAHL. Planta Medica, 2019, 85(11/12), 911-916. Doi: 10.1055/a-0877-7255
Popp JR, Petrakis EA, Angelis A, Halabalaki M, Bonn G, Stuppner H, Skaltsouis LA. Rapid isolation of acidic cannabinoids from Cannabis sativa L. using pH-zone-refining centrifugal partition chromatography. Journal of Chromatography A, 2019, 1599, 196-202. Doi: 10.1016/j.chroma.2019.04.048
Rainer B, Revoltella S, Mayr F, Moesslacher J, Scalfari V, Kohl R, Waltenberger B, Pagitz K, Siewert B, Schwaiger S, Stuppner H. From bench to counter: Discovery and validation of a peony extract as tyrosinase inhibiting cosmeceutical. European Journal of Medicinal Chemistry, 2019, 184, No. 111738. Doi: 10.1016/j.ejmech.2019.111738
Revoltella S, Rainer B, Waltenberger B, Schwaiger S, Stuppner H. HPTLC Autography Based Screening and Isolation Mushroom Tyrosinae Inhibitors of European Plant Species. Chemistry Biodiversity,2019, 16, e1800541 Doi: 10.1002/cbdv.201800541
Siewert B, Vrabl P, Hammerle F, Bingger I, Stuppner H. A convenient workflow to spot photosensitizers revealed photo-activity in basidiomycetes. RSC Advanced, 2019, 9(8), 4545-4552. Doi: 10.1039/C8RA10181G
Siewert B, Stuppner H. The photoactivity of natural products – An overlooked potential of phytomedicines? Phytomedicine, 2019, 60, No. 152985. Doi: 10.1016/j.phymed.2019.152985
2018
Becker K, Schwaiger S, Waltenberger B, Fuchs D, Pezzei CK, Schennach H, Stuppner H, Gostner JM. Immunomodulatory Effects of Diterpene Quinone Derivatives from the Roots of Horminum pyrenaicum in Human PBMC. Oxidative Medicine and Cellular Longevity,2018, Article ID 2980295. Doi: 10.1155/2018/2980295
Cheung SY, Werner M, Esposito L, Troisi T, Cantone V, Liening S, König S, Gerstmeier J, Koeberle Bilancia R, Rizza R, Rossi A, Roviezzo F, Temml V, Schuster D, Stuppner H, Schubert-Zsilavecz M, Werz O, Hanke H, Pace S. Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammation. European Journal of Medicinal Chemistry, 2018, 156, 815-830. Doi: 10.1016/j.ejmech.2018.07.031
Engels N, Waltenberger B, Stuppner H, Michalak B, Kiss AK, Huynh L, Tran H. Inhibition of Pro‐Inflammatory Functions of Human Neutrophils by Constituents of Melodorum fruticosum Leaves. Chemistry & Biodiversity, 2018, 15(11), e1800269 Doi: 10.1002/cbdv.201800269
Ferraz Gomes A, Ganzera M, Schwaiger S, Stuppner H, Halabalaki M, Almeide MP, Leite MF, Amaral JG, David JM. Simultaneous determination of iridoids, phenylpropanoids and flavonoids in Lippia alba extracts by micellar electrokinetic capillary chromatography. Microchemical Journal, 2018, 138, 494-500. Doi: 10.1016/j.microc.2018.02.003
Gibitz-Eisath N, Sturm S, Stuppner H. Supercritical Fluid Chromatography in Natural Product Analysis – An Update. Planta Medica, 2018, 84(6/7), 361-371. Doi: 10.1055/s-0037-1599461
Gibitz-Eisath N, Eichberger M, Gruber R, Sturm S, Stuppner H. Development and validation of a rapid ultra-high performance liquid chromatography diode array detector method for Verbena officinalis L.. Journal of Pharmaceutical and Biomedical Analysis, 2018, 160, 160-167. Doi: 10.1016/j.jpba.2018.07.047
Gufler V, Nguyen Ngoc H, Stuppner H, Ganzera M. Capillary electrophoresis as a fast and efficient alternative for the analysis of Urceola rosea leaf extracts. Fitoterapia, 2018, 125, 1-5. Doi: 10.1016/j.fitote.2017.12.007
Hartmann A, Ganzera M, Karsten U, Skhirtladze A, Stuppner H. Phytochemical and Analytical Characterization of Novel Sulfated Coumarins in the Marine Green Macroalga Dasycladus vermicularis (Scopoli) Krasser. Molecules, 2018, 23(11), 2735. Doi: 10.3390/molecules23112735
Heilos D, Röhrl C, Pirker C, Englinger B, Baier D, Mohr T, Schwaiger M, Iqbal SM, Van Schoonhoven S, Klavins K, Eberhart T, Windberger U, Taibon J, Sturm S, Stuppner H, Koellensperger G, Dornetshuber-Fleiss R, Jäger W, Lemmens-Gruber R, Berger W. Altered membrane rigidity via enhanced endogenous cholesterol synthesis drives cancer cell resistance to destruxins. Oncotarget, 2018, 9(39), 25661-25680. Doi: 10.18632/oncotarget.25432
Kiechl S, Pechlaner R, Willeit P, Notdurfter M, Paulweber B, Willeit K, Werner P, Ruckenstuhl C, Iglseder B, Weger S, Mairhofer B, Gartner M, Kedenko L, Chmelikova M, Stekovic S, Stuppner H, Oberhollenzer F, Kroemer G, Mayr M, Eisenberg T, Tilg H, Madeo F, Willeit J. Higher spermidine intake is linked to lower mortality: a prospective population-based study. American Journal of Clinical Nutrition, 2018, 108(2), 371-380. Doi: 10.1093/ajcn/nqy102
Liu R, Heiss EH, Waltenberger B, Blazevic T, Schachner D, Jiang B, Krystof V, Liu W, Schwaiger S, Pena-Rodriguez LM, Breuss JM, Stuppner H, Dirsch V, Atanasov AG. Constituents of Mediterranean Spices Counteracting Vascular Smooth Muscle Cell Proliferation: Identification and Characterization of Rosmarinic Acid Methyl Ester as a Novel Inhibitor. Molecular Nutrition & Food Research, 2018, 62(7), e1700860. Doi: 10.1002/mnfr.201700860
Mutschlechner B, Schwaiger S, Tran TVA, Stuppner H. Development of a selective HPLC-DAD/ELSD method for the qualitative and quantitative assessment of commercially available Eurycoma longifolia products and plant extracts. Fitoterapia, 2018, 124, 188-192. Doi: 10.1016/j.fitote.2017.11.015
Mutschlechner B, Rainer B, Schwaiger S, Stuppner H. Tyrosinase Inhibitors from the Aerial Parts of Wulfenia carinthiaca Jacq. Chemistry & Biodiversity, 2018, 15, e1800014. Doi: 10.1002/cbdv.201800014
Nguyen Ngoc H, Nghiem, DT, Pham TLG, Stuppner H, Ganzera M. Phytochemical and analytical characterization of constituents in Urceola rosea (Hook. & Arn.) D.J. Middleton leaves. Journal of Pharmaceutical and Biomedical Analysis, 2018, 149, 66-69. Doi: 10.1016/j.jpba.2017.10.031
Pein H, Ville A, Pace S, Temml V, Garscha U, Raasch M, Alsabil K, Viault G, Dinh CP, Guilet D, Troisi F, Neukirch K, König S, Bilancia R, Waltenberger B, Stuppner H, Wallert M, Lorkowski S, Weinigel C, Rummler S, Birringer M, Roviezzo F, Sautebin L, Helesbeux JJ, Séraphin D, Mosig AS, Schuster D, Rossi A, Richomme P, Werz O, Koeberle A. Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase. Nature Communications,2018, 9, Article number 3834. Doi: 10.1038/s41467-018-06158-5
Piwowarskia J, Waltenberger B, Stuppner H, Kiss AK, Granica S. The analysis of phenolic compounds from the aerial parts of Eupatorium cannabinum L. subsp. cannabinum. Biochemical Systematics and Ecology, 2018, 79, 37-43. Doi: 10.1016/j.bse.2018.05.001
Pompermaier L, Marzocco S, Adesso S, Monizi M, Schwaiger S, Neinhuis C, Stuppner H, Lautenschläger T. Medicinal plants of northern Angola and their anti-inflammatory properties. Journal of Ethnopharmacology, 2018, 216, 26-36. Doi: 10.1016/j.jep.2018.01.019
Pompermaier L, Heiss EH, Alilou M, Mayr F, Monizi M, Lautenschläger T, Schuster D, Schwaiger S, Stuppner H. Dihydrochalcone Glucosides from the Subaerial Parts of Thonningia sanguinea and Their in Vitro PTP1B Inhibitory Activities. Journal of Natural Products, 2018, 81(9), 2091-2100. Doi: 10.1021/acs.jnatprod.8b00450
Revoltella S, Baraldo G, Waltenberger B, Schwaiger S, Kolfer P, Moesslacher J, Huber-Seidel A, Pagitz K, Kohl R, Jansen-Duerr P, Stuppner H. Identification of the NADPH Oxidase 4 Inhibiting Principle of Lycopus europaeus. Molecules,2018, 23(3), 653. Doi: 10.3390/molecules23030653
Schinkovitz A, Le Pogam P, Derbré S, Roy-Vessieres E, Blanchard P, Thirumaran SL, Breard D, Aumond MC, Zehl M, Urban E, Kaur A, Jäger N, Hofer S, Kopp B, Stuppner H, Baglin I, Seraphin D, Tomasi S, Henrion D, Boustie J, Richomme P. Secondary metabolites from lichen as potent inhibitors of advanced glycation end products and vasodilative agents. Fitoterapia, 2018, 131, 182-188. Doi: 10.1016/j.fitote.2018.10.015
Waltenberger B, Halabalaki M, Schwaiger S, Adamopoulos N, Allouche N, Fiebich BL, Hermans N, Jansen-Dürr P, Kesternich V, Pieters L, Schönbichler S, Skaltsounis A-L, Tran H, Trougakos IP, Viljoen A, Wolfender J-L, Wolfrum C, Xynos N, Stuppner H. Novel Natural Products for Healthy Ageing from the Mediterranean Diet and Food Plants of Other Global Sources—The MediHealth Project. Molecules,2018, 23(5), 1097. Doi: 10.3390/molecules23051097
2017
Cavinato M, Waltenberger B, Baraldo G, Grade CVC, Stuppner H, Jansen-Dürr P. Plant extracts and natural compounds used against UVB-induced photoaging. Biogerontology, 2017, 18(4), 499-516. Doi: 10.1007/s10522-017-9715-7
Dreier D, Latkolik S, Rycek L, Schnürch M, Dymáková A, Atanasov AG, Ladurner A, Heiss EH, Stuppner H, Schuster D, Mihovilovic MD, Dirsch VM. Linked magnolol dimer as a selective PPARγ agonist – Structure-based rational design, synthesis, and bioactivity evaluation. Scientific Reports, 2017, 7, 13002. Doi: 10.1038/s41598-017-12628-5
Haller J, Schwaiger S, Stuppner H, Gafner F, Ganzera M. Isolation of three triterpene saponins, including two new oleanane derivatives, from Soldanella alpina and Hydrophilic Interaction Liquid Chromatography-Evaporative Light Scattering Detection of these three saponins in four Soldenella species. Phytochemical Analysis, 2017, 28(6), 567-574. Doi: 10.1002/pca.2706
Hochleitner J, Akram M, Ueberall M, Davis RA, Waltenberger B, Stuppner H, Sturm S, Ueberall F, Gostner JM, Schuster D. A combinatorial approach for the discovery of cytochrome P450 2D6 inhibitors from nature. Scientific Reports, 2017, 7, 8071. Doi: 10.1038/s41598-017-08404-0
Khan SY, Awad EM, Oszwald A, Mayr M, Yin X, Waltenberger B, Stuppner H, Lipovac M, Pavel U, Breuss JM. Premature senescence of endothelial cells upon chronic exposure to TNFα can be prevented by N-acetyl cysteine and plumericin. Scientific Reports, 2017, 7, 39501. Doi: 10.1038/srep39501
Mailainer C, Schachner D, Sangiovanni E, Atanasov AG, Schwaiger S, Stuppner H, Heiss EH, Dirsch VM. Eurycomalactone Inhibits Expression of Endothelial Adhesion Molecules at a Post-Transcriptional Level. Journal of Natural Products, 2017, 80(12), 3186-3193. Doi: 10.1021/acs.jnatprod.7b00503
Marzocco S, Adesso S, Alilou M, Stuppner H., Schwaiger S. Anti-Inflammatory and Anti-Oxidant Potential of the Root Extract and Constituents of Doronicum austriacum. Molecules, 2017, 22(6), 1003. Doi: 10.3390/molecules22061003
Pataczek L, Cheilari A, Zikeli S, Sturm S, Stuppner H, Gruber S. Centaurium erythraea Cultivation Method for Optimal Yield and Product Quality. Journal of Herbs, Spices & Medicinal Plants, 2017, 23(3), 193-215. Doi: 10.1080/10496475.2017.1295414
Peduto A, Scuotto M, Krauth V, Roviezzo F, Rossi A, Temml V, Esposito V, Stuppner H, Schuster D, D´Agostino B., Schiraldi C, De Rosa M, Werz O, Filosa R. Optimization of benzoquinone and hydroquinone derivatives as potent inhibitors of human 5-lipoxygenase. European Journal of Medicinal Chemistry, 2017, 127, 715-726. Doi: 10.1016/j.ejmech.2016.10.046
Schäfer S, Schwaiger S, Stuppner H. Aristolic Acid Derivates from the Bark of Antidesma ghaesembilla. Planta Medica, 2017, 83(12/13), 1097-1102. Doi: 10.1055/s-0043-110141
Taibon J, Sturm S, Strasser H, Stuppner H. Combination of a Quechers-Based extraction protocol with a fast and selective UHPLC-QTOF-MS assay for the detection and quantification of Metarhizium brunneum metabolites from honey samples. SOJ Pharmacy & Pharmaceutical Sciences, 2017, 4(1), 1-5. Doi: 10.15226/2374-6866/4/1/00147
Temml V, Garscha U, Romp E, Schubert G, Gerstmeier J, Kutil Z, Matuszczak B, Waltenberger B, Stuppner H, Werz O, Schuster D. Discovery of the first dual inhibitor of the 5-lipoxygenase-activating protein and soluble epoxide hydrolase using pharmacophore-based virtual screening. Scientific Reports, 2017, 7, 42751. Doi: 10.1038/srep42751
Vuorinen A, Engeli RT, Leugger S, Bachmann F, Akram M, Atanasov AG, Waltenberger B, Temml V, Stuppner H, Krenn L, Ateba SB, Njamen D, Davis RA, Odermatt A, Schuster D. Potential Antiosteoporotic Natural Product Lead Compounds That Inhibit 17β-Hydroxysteroid Dehydrogenase Type 2. Journal of Natural Products, 2017, 80(4), 965-974. Doi: 10.1021/acs.jnatprod.6b00950
2016
Alsabil K, Suor-Cherer S, Koeberle A, Viault G, Lavaud A, Temml V, Waltenberger B, Schuster D, Litaudon M, Lorkowski S, de Vaumas R, Helesbeux JJ, Guilet D, Stuppner H, Werz O, Seraphin D, Richomme P. Semisynthetic and Natural Garcinoic Acid Isoforms as New mPGES-1 Inhibitors. Planta Medica, 2016, 82 (11/12), 1110-1116. Doi: 10.1055/s-0042-108739
Antal DS, Pinzaru I, Borcan F, Marti TD, Ledeti I, Coricovac D, Schwaiger S, Stuppner H, Dehelean CA, Ollivier E, Soica C. Inclusion Complexes of the Aurone Sulfuretin and the Chalcone Butein from Cotinus coggygria Wood in Two Cyclodextrin Types: First data on physico-chemical properties. Revista De Chimie, 2016 67(6), 1104-1109.
Cheilari A, Sturm S, Intelmann D, Seger C, Stuppner H. Head-to-Head Comparison of Ultra-High-Performance Liquid Chromatography with Diode Array Detection versus Quantitative Nuclear Magnetic Resonance for the Quantitative Analysis of the Silymarin Complex in Silybum marianum Fruit Extracts. Journal of Agricultural and Food Chemistry, 2016, 64(7), 1618-1626. Doi: 10.1021/acs.jafc.5b05494
Heiss EH, Liu R, Waltenberger B, Khan S, Schachner D, Kollmann P, Zimmermann K, Cabaravdic M, Uhrin P, Stuppner H, Breuss JM, Atanasov AG, Dirsch VM. Plumericin inhibits proliferation of vascular smooth muscle cells by blocking STAT3 signaling via S-glutathionylation. Scientific reports, 2016, 6, 20771. Doi: 10.1038/srep20771
Papadakis ES, Robson N, Yeomans A, Bailey S, Laversin S, Beer S, Sayan A, Ashton-Key M, Schwaiger S, Stuppner H, Troppmair J, Packham G, Cutress R. A combination of trastuzumab and BAG-1 inhibition synergistically targets HER2 positive breast cancer cells. Oncotarget, 2016, 7(14), 18851-18864. Doi: 10.18632/oncotarget.7944
Papadakis ES, Barker CR, Syed H, Reeves T, Schwaiger S, Stuppner H, Troppmair J, Blaydes JP, Cutress RI. The Bag-1 inhibitor, Thio-2, reverses an atypical 3D morphology driven by Bag-1L overexpression in a MCF-10A model of ductal carcinoma in situ. Oncogenesis, 2016, 5, e215. Doi: 10.1038/oncsis.2016.10
Schäfer S, Salcher S, Seiter M, Ranninger C, Moest M, Obexer P, Huber CG, Ausserlechner MJ, Schwaiger S, Stuppner H. Characterization of the XIAP-Inhibiting Proanthocyanidin Fraction of the Aerial Parts of Ephedra sinica. Planta Medica, 2016, 82(11/12), 973-985. Doi: 10.1055/s-0042-107253
Schaible AM, Filosa R, Krauth V, Temml V, Pace S, Garscha U, Liening S, Weinigel C, Rummler S, Schieferdecker S, Nett M, Peduto A, Collarile S, Scuott M, Roviezzo F, Spaziano G, De Rosa M, Stuppner H, Schuster D, D´Agostino, B, Werz O. The 5-lipoxygenase inhibitor RF-22c potently suppresses leukotriene biosynthesis in cellulo and blocks bronchoconstriction and inflammation in vivo. Biochemical Pharmacology, 2016, 112, 60-71. Doi: 10.1016/j.bcp.2016.04.019
Scharinger B, Messner B, Türkcan A, Schuster D, Vuorinen A, Pitterl F, Heinz K, Arnhard K, Laufer G, Grimm M, Stuppner H, Oberacher H, Eller P, Ritsch A, Bernhard D. Leoligin, the major lignan from edelweiss, inhibits 3-hydroxy-3-methyl-glutaryl-CoA reductase and reduces cholesterol levels in ApoE −/− mice. Journal of Molecular and Cellular Cardiology, 2016, 99, 35-46. Doi: 10.1016/j.yjmcc.2016.08.003
Waltenberger B, Garscha U, Temml V, Liers J, Werz O, Schuster D, Stuppner H. Discovery of Potent Soluble Epoxide Hydrolase (sEH) Inhibitors by Pharmacophore-Based Virtual Screening. Journal of Chemical Information and Modeling, 2016, 56(4), 747-762. Doi: 10.1021/acs.jcim.5b00592
Waltenberger B, Atanasov AG, Heiss EH, Bernhard D, Rollinger JM, Breuss JM, Schuster D, Bauer R, Kopp B, Franz C, Bochkov V, Mihovilovic MD, Dirsch VM, Stuppner H. Drugs from nature targeting inflammation (DNTI): a successful Austrian interdisciplinary network project. Monatshefte für Chemie, 2016, 147(3), 479-491. Doi: 10.1007/s00706-015-1653-y
Wang L, Ladurner A, Latkolik S, Schwaiger S, Linder T, Hosek J, Palme V, Schilcher N, Polanský O, Heiss EH, Stangl H, Mihovilovic MD, Stuppner H, Dirsch VM, Atanasov AG. Leoligin, the Major Lignan from Edelweiss (Leontopodium nivale subsp. alpinum), Promotes Cholesterol Efflux from THP-1 Macrophages. Journal of Natural Products, 2016, 79(6), 1651-1657. Doi: 10.1021/acs.jnatprod.6b00227
2015
Aguiriano-Moser V, Svejda B, Li ZX, Sturm S, Stuppner H, Ingolic E, Höger H, Siegl V, Meier-Allard N, Sadjak A, Pfragner R. Ursolic acid from Trailliaedoxa gracilis induces apoptosis in medullary thyroid carcinoma cells. Molecular medicine reports, 2015, 12(4), 5003-5011. Doi: 10.3892/mmr.2015.4053
Atanasov AG, Waltenberger B, Pferschy-Wenzig EM, Linder T, Wawrosch C, Uhrin P, Temml V, Wang L, Schwaiger S, Heiss EH, Rollinger J, Schuster D, Breuss JM, Bochov V, Mihovilovic MD, Kopp B, Bauer R, Dirsch VM, Stuppner H. Discovery and resupply of pharmacologically active plant-derived natural products: A review. Biotechnology Advances, 2015, 33(8), 1582-1614. Doi: 10.1016/j.biotechadv.2015.08.001
Taibon J, Sturm S, Seger C, Strasser OH, Stuppner H. Quantitative Assessment of Destruxins from Strawberry and Maize in the Lower ppb Range: Combination of a QuEChERS-based Extraction Protocol with a Fast and Selective UHPLC-QTOF-MS Assay. Journal of Agricultural and Food Chemistry, 2015, 63(23), 5707-5713. Doi: 10.1021/acs.jafc.5b01562
Taibon J, Ankli A, Schwaiger S, Magnenat C, Boka VI, Simoes-Pires C, Aligiannis N, Cuendet M, Skaltsounis AL, Reich E, Stuppner H. Prevention of false positive results: development of an HPTLC autographic assay for the detection of natural tyrosinase inhibitors. Planta Medica, 2015, 81(12/13), 1198-1204. Doi: 10.1055/s-0035-1546250
Taibon J, Sturm S, Seger C, Werth M, Strasser H, Stuppner H. Supercritical Fluid Chromatography as an Alternative Tool for the Qualitative and Quantitative Analysis of Metarhizium brunneum Metabolites from Culture Broth. Planta Medica, 2015, 81(18), 1736-1743. Doi: 10.1055/s-0035-1557823
Tran TVA, Mailaner C, Schwaiger S, Hung T, Atanasov AG, Heiss EH, DIRSCH V, Stuppner H. Screening of Vietnamese medicinal plants for NF-κB signaling inhibitors: Assessing the activity of flavonoids from the stem bark of Oroxylum indicum. Journal of Ethnopharmacology, 2015, 159, 36-42. Doi: 10.1016/j.jep.2014.10.012
Waltenberger B, Liu R., Atanasov AG, Schwaiger S, Heiss EH, Dirsch VM, Stuppner H. Nonprenylated Xanthones from Gentiana lutea, Frasera caroliniensis, and Centaurium erythraea as Novel Inhibitors of Vascular Smooth Muscle Cell Proliferation. Molecules, 2015, 20(11), 20381-20390. Doi: 10.3390/molecules201119703
Winekenstädde D, Angelis A, Waltenberger B, Schwaiger S, Tchoumtchoua J, König S, Werz O, Aligiannis N, Skaltsounis AL, Stuppner H. Phytochemical profile of the aerial parts of Sedum sediforme and anti-inflammatory activity of myricitrin. Natural Product Communications, 2015, 10(1), 83-88.
2014
Fakhrudin N, Waltenberger B, Cabaravdic M, Atanasov AG, Malainer C, Schachner D, Heiss EH, Liu R, Noha SM, Grzywacz AM, Mihaly-Bison J, Awad EM, Schuster D, Breuss JM, Rollinger JM, Bochkov V, Stuppner H, Dirsch VM. Identification of plumericin as a potent new scaffold inhibitor of the NF-kB pathway with anti-inflammatory activity in vitro and in vivo. British Journal of Pharmacology, 2014, 171(7), 1676-1686. Doi: 10.1111/bph.12558
Heiss EH, Tran TVH, Zimmermann K, Schwaiger S, Vouk C, Mayerhofer B, Malainer C, Atanasov AG, Stuppner H, Dirsch VM. Identification of Chromomoric Acid C‑I as an Nrf2 Activator in Chromolaena odorata. Journal of Natural Products, 2014, 77(3), 503-508. Doi: 10.1021/np400778m
Krautscheid Y, Senning CJA, Sartori SB, Singewald N, Schuster D, Stuppner H. Pharmacophore Modeling, Virtual Screening, and in Vitro Testing Reveal Haloperidol, Eprazinone, and Fenbutrazate as Neurokinin Receptors Ligands. Journal of Chemical Information and Modeling, 2014, 54(6), 1747-1757. Doi: 10.1021/ci500106z
Öttl S, Hubert J, Nuzzilard J-M, Stuppner H, Renault J-H, Rollinger JM. Dereplication of depsides from the lichen Pseudevernia furfuracea by centrifugal partition chromatography combined to 13C nuclear magnetic resonance pattern recognition. Analytica Chimica Acta, 2014, 846, 60-67. Doi: 10.1016/j.aca.2014.07.009
Picker P, Vogl S, McKinnon R, Mihaly-Bison J, Binder M, Atanasov AG, Fakhrudin N, Grzywacz AM, Heiss EH, Zehl M, Saukel J, Wawrosch C, Schinkovitz A, Waltenberger B, Bauer R, Rollinger JM, Stuppner H, Dirsch VM, Bochkov V, Reznicek G, Kopp B. Plant extracts in cell-based anti-inflammatory assays—Pitfalls and considerations related to removal of activity masking bulk components. Phytochemistry Letters, 2014, 10, xli–xlvii, Doi: 10.1016/j.phytol.2014.04.001
Stille JS, Jäger M, Dickore WB, Ehlers K, Holzhauer SIJ, Mayland-Quellhorst E, Safer S, Schwaiger S, Stuessy TF, Stuppner H, Wissemann V. Chromosome numbers of the Edelweiss, Leontopodium (Asteraceae, Compositae - Gnaphalieae). Edinburgh Journal of Botany, 2014, 71(1), 23-33. Doi: 10.1017/S0960428613000243
Strommer B, Khom S, Kastenberger I, Cicek SS, Stuppner H, Schwarzer C, Hering S. A Cycloartane Glycoside Derived from Actaea racemosa L. Modulates GABAA Receptors and Induces Pronounced Sedation in Mice. The Journal of Pharmacology and Experimental Therapeutics, 2014, 351(2), 234-242. Doi: 10.1124/jpet.114.218024
Taibon J, Sturm S, Seger C, Parth M, Strasser H, Stuppner H. Development of a fast and selective UHPLC-DAD-QTOF-MS/MS method for the qualitative and quantitative assessment of destruxin profiles. Analytical and Bioanalytical Chemistry, 2014, 406(29), 7623-7632. Doi: 10.1007/s00216-014-8203-z
Tappeiner J, Vasiliou A, Ganzera M, Fessas D, Stuppner H, Papageorgiou VP, Assimopoulou A. Quantitative determination of alkannins and shikonins in endemic Mediterranean Alkanna species. Biomedical Chromatography, 2014, 28(7), 923-933. Doi: 10.1002/bmc.3096
Tran TVH, Malainer C, Schwaiger S, Atanasov AG, Heiss EH, Dirsch VM, Stuppner H. NF-κB Inhibitors from Eurycoma longifolia. Journal of Natural Products, 2014, 77(3), 483-488. Doi: 10.1021/np400701k
Wang L, Waltenberger B, Pferschy-Wenzig E-M, Blunder M, Liu X, Malainer C, Blazevic T, Schwaiger S, Rollinger JM, Heiss EH, Schuster D, Kopp B, Bauer R, Stuppner H, Dirsch VM, Atanasov AG. Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review. Biochemical Pharmacology, 2014, 92(1), 89-92, Doi: 10.1016/j.bcp.2014.07.018
Wawrosch C, Schwaiger S, Stuppner H, Kopp B. Lignan formation in hairy root cultures of Edelweiss (Leontopodium nivale ssp. alpinum (Cass.) Greuter). Fitoterapia, 2014, 97, 219-223. Doi: 10.1016/j.fitote.2014.06.008
2013
Atanasov AG, Wang JN, Gu SP, Bu J, Kramer MP, Baumgartner L, Fakhrudin N, Ladurner A, Malainer C, Vuorinen A, Noha SM, Schwaiger S, Rollinger JM, Schuster D, Stuppner H, Dirsch VM, Heiss EH. Honokiol: A non-adipogenic PPARγ agonist from nature. Biochimica et biophysica acta,2013, 1830(10), 4813-4819. Doi: 10.1016/j.bbagen.2013.06.021
Do TCMV, Nguyen TD, Tran H, Stuppner H, Ganzera M. Analysis of alkaloids in Lotus (Nelumbo nucifera Gaertn.) leaves by non-aqueous capillary electrophoresis using ultraviolet and mass spectrometric detection. Journal of Chromatography A, 2013, 1302, 174-180. Doi: 10.1016/j.chroma.2013.06.002
Enthammer M, Papadakis ES, Gachet MS, Deutsch M, Schwaiger S, Koziel K, Ashraf MI, Khalid S, Wolber G, Packham G, Cutress RI, Stuppner H, Troppmair J. Isolation of a Novel Thioflavin S-Derived Compound that Inhibits BAG-1-Mediated Protein Interactions and Targets BRAF Inhibitor-Resistant Cell Lines. Molecualar cancer therapeutics, 2013, in print, Doi: 10.1158/1535-7163.MCT-13-0142
Hofer D, Schwach G, Tabrizi-Wizsy NG, Sadjak A, Sturm S, Stuppner H, Pfragner R. Christia vespertilionis plant extracts as novel antiproliferative agent against human neuroendocrine tumor cells. Oncology Reports, 2013, 29(6), 2219-2226. Doi: 10.3892/or.2013.2367
Högner C, Sturm S, Seger C, Stuppner H. Development and validation of a rapid ultra-high performance liquid chromatography diode array detector method for Vitex agnus-castus. Journal of Chromatography B, 2013, 927, 181-190. Doi: 10.1016/j.jchromb.2013.02.037
Messner B, Kern J, Wiedemann D, Schwaiger S, Türkcan A, Ploner C, Trockenbacher A, Aumayr K, Bonaros N, Laufer G, Stuppner H, Untergasser G, Bernhard D. 5-Methoxyleoligin, a Lignan from Edelweiss, Stimulates CYP26B1-Dependent Angiogenesis In Vitro and Induces Arteriogenesis in Infarcted Rat Hearts In Vivo. PLoS One, 2013, 8(3), e58342. Doi: 10.1371/journal.pone.0058342
Neu V, Bielow C, Gostomski I, Wintringer R, Braun R, Reinert K, Schneider P, Stuppner H, Huber CG. Rapid and Comprehensive Impurity Profiling of Synthetic Thyroxine by Ultrahigh-Performance Liquid Chromatography–High-Resolution Mass Spectrometry. Analytical Chemistry, 2013, 85(6), 3309-3317. Doi: 10.1021/ac303722j
Neu V, Bielow C, Schneider P, Braun R, Stuppner H, Reinert K, Huber C.G. UHPLC-HRMS-Experimente planen und auswerten Beispiel Thyroxin. Nachrichten aus der Chemie, 2013, 61(4), 455-458.
Neu V, Bielow C, Schneider P, Reinert K, Stuppner H, Huber CG. Investigation of Reaction Mechanisms of Drug Degradation in the Solid State: A Kinetic Study Implementing Ultrahigh-Performance Liquid Chromatography and High-Resolution Mass Spectrometry for Thermally Stressed Thyroxine. Analytical Chemistry 2013, 85(4), 2385-2390. Doi: 10.1021/ac303404e
Pezzei C, Kopp B, Stuppner H, Huck C.W. Advances on an Infrared Hyperspectral Spectroscopy Platform for Medicianl Plant Materials Analysis and its Impact on In vivo Studies. Current Bioactive Compounds 2013, (9(3), 235-246. Doi: 10.2174/15734072113099990015
Russel A, Safer S, Weiss-Schneeweiss H, Temsch E, Stuppner H, Stuessy TF, Samuel R. Chromosome counts and genome size of Leontopodium species (Asteraceae: Gnaphalieae) from south-western China. Botanical Journal of the Linnean Society, 2013, 171(3), 627-636. Doi: 10.1111/boj.12011
Seger C, Sturm S, Stuppner H. Mass spectrometry and NMR spectroscopy: modern high-end detectors for high resolution separation techniques – state of the art in natural product HPLC-MS, HPLC-NMR, and CE-MS hyphenations. Natural Product Reports, 2013, 30(7), 970-987. Doi: 10.1039/C3NP70015A
Temml V, Kühnl S, Schuster D, Schwaiger S, Stuppner H, Fuchs D. Interaction of Carthamus tinctorius lignan arctigenin with the binding site of tryptophan-degrading enzyme indoleamine 2,3-dioxygenase. FEBS Open Bio, 2013, 450-452(3). Doi: 10.1016/j.fob.2013.08.008
2012
Bauer J, Kühnl S, Rollinger JM, Scherer O, Northoff H, Stuppner H, Werz O, Köberle A. Carnosol and Carnosic Acids from Salvia officinalis Inhibit Microsomal Prostaglandin E2 Synthase-1. Journal of Pharmacology and Experimental Therapeutics, 2012, 342(1), 169-176. Doi: 10.1124/jpet.112.193847
Bauer J, Waltenberger B, Noha SM, Schuster D, Rollinger JM, Boustie J, Chollet M, Stuppner H, Werz O. Discovery of Depsides and Depsidones from Lichen as Potent Inhibitors of Microsomal Prostaglandin E2 Synthase-1 Using Pharmacophore Models. ChemMedChem, 2012, 7(12), 2077-2081. Doi: 10.1002/cmdc.201200345
Do TCMV, Nguyen TD, Tran H, Stuppner H, Ganzera M. Quantitative Determination of Phenolic Compounds in Lotus (Nelumbo nucifera) Leaves by Capillary Zone Electrophoresis. Planta Medica, 2012, 78(16), 1796-1799. Doi: 10.1055/s-0032-1315258
Ganzera M, Greifeneder V, Schwaiger S, Stuppner H. Chemical profiling of Edelweiss (Leontopodium alpinum Cass.) extracts by micellar electrokinetic capillary chromatography. Fitoterapia, 2012, 83(8), 1680-1686. Doi: 10.1016/j.fitote.2012.09.023
Heiss EH, Baumgartner L, Schwaiger S, Heredia RJ, Atanasov AG, Rollinger JM, Stuppner H, Dirsch V. Ratanhiaphenol III from Ratanhiae Radix is a PTP1B Inhibitor. Planta Medica, 2012, 78(7), 678-681. Doi: 10.1055/s-0031-1298242
Ladurner A, Atanasov AG, Heiss EH, Baugartner L, Schwaiger S, Rollinger JM, Stuppner H, Dirsch M. 2-(2,4-dihydroxyphenyl)-5-(E)-propenylbenzofuran promotes endothelial nitric oxide synthase activity in human endothelial cells. Biochemical Pharmacology, 2012, 84(6), 804-812. Doi: 10.1016/j.bcp.2012.06.029
Noha SM, Jazzar B, Kühnl S, Rollinger JM, Stuppner H, Schaible AM, Werz O, Wolber G, Schuster D. Pharmacophore-based discovery of a novel cytosolic phospholipase A2α inhibitor. Bioorganic & Medicinal Chemistry Letters, 2012, 22(2), 1202-1207. Doi: 10.1016/j.bmcl.2011.11.093
Pieri V, Sturm S, Seger C, Franz C, Stuppner H. 1H NMR-based metabolic profiling and target analysis: a combined approach for the quality control of Thymus vulgaris. Metabolomics, 2012, 8(2), 335-346. Doi: 10.1007/s11306-011-0317-0
Remias D, Schwaiger S, Aigner S, Leya T, Stuppner H, Lütz C. Characterization of an UV- and VIS-absorbing, purpurogallin-derived secondary pigment new to algae and highly abundant in Mesotaenium berggrenii (Zygnematophyceae, Chlorophyta), an extremophyte living on glaciers. FEMS Microbiology Ecology, 2012, 79(3), 638-648. Doi: 10.1111/j.1574-6941.2011.01245.x
Steinmann D, Baumgartner RR, Heiss EH, Bartenstein S, Atanasov AG, Dirsch VM, Ganzera M, Stuppner H. Bioguided Isolation of (9Z)-Octadec-9-enoic Acid from Phellodendron amurense Rupr. and Identification of Fatty Acids as PTP1B Inhibitors. Planta Medica, 2012, 78(3), 219-224. Doi: 10.1055/s-0031-1280377
Zeller I, Wiedemann D, Schwaiger S, Stelzmüller M, Kreutmayer S, Leberfing O, Stuppner H, Bernhard D. Inhibition of cell surface expression of endothelial adhesion molecules by ursolic acid prevents intimal hyperplasia of venous bypass grafts in rats. European Journal Of Cardio-Thoracic Surgery, 2012;, 2(5), 878-884. Doi: 10.1093/ejcts/ezs128
2011
Aberham A, Pieri V, Croom Jr EM, Ellmerer E, Stuppner H. Analysis of iridoids, secoiridoids and xanthones in Centaurium erythraea, Frasera caroliniensis and Gentiana lutea using LC–MS and RP-HPLC. Journal of Pharmaceutical and Biomedical Analysis, 2011, 54(3), 517-525. Doi: 10.1016/j.jpba.2010.09.030
Baumgartner L, Schwaiger S, Stuppner H. Quantitative analysis of anti-inflammatory lignan derivatives in Ratanhiae radix and its tincture by HPLC–PDA and HPLC–MS. Journal of Pharmaceutical and Biomedical Analysis, 2011, 56(3), 546-552. Doi: 10.1016/j.jpba.2011.06.016
Baumgartner L, Sosa S, Atanasov AG, Bodensieck A, Fakhrudin N, Bauer J, Del Favero G, Ponti C, Heiss EH, Schwaiger S, Ladurner A, Widowitz U, Della Loggia R, Rollinger JM, Werz O, Bauer R, Dirsch VM, Tubaro A, Stuppner H. Lignan Derivatives from Krameria lappacea Roots Inhibit Acute Inflammation in Vivo and Pro-inflammatory Mediators in Vitro. Journal of Natural Products, 2011, 74(8), 1779-1786. Doi: 10.1021/np200343t
Cicek SS, Aberham A, Ganzera M, Stuppner H. Quantitative analysis of cycolartane glycosides in black cohosh rhizomes and dietary supplements by RRLC-ELSD and RRLC-qTOF-MS. Analytical and Bioanalytical Chemistry, 2011, 400(8), 2597-2605. Doi: 10.1007/s00216-010-4068-y
Duwensee K, Schwaiger S, Tancevksi I, Eller K, Van Eck M, Makrt P, Linder T, Stanzl U, Ritsch A, Patsch JR, Schuster D, Stuppner H, Bernhard D, Eller P. Leoligin, the major lignan from Edelweiss, activates cholesteryl ester transfer protein. Atherosclerosis, 2011, 219/1, 109-115. Doi: 10.1016/j.atherosclerosis.2011.07.023
Grienke U, Mihaly-Bison J, Schuster D, Afonyushkin T, Binder M, Guan S-H, Cheng C-R, Wolber G, Stuppner H, Guo D-A, Bochkov VN, Rollinger JM. Pharmacophore-based discovery of FXR-agonists. Part II: Identification of bioactive triterpenes from Ganoderma lucidum. Bioorganic & Medicinal Chemistry, 2011, 19/22, 6779-6791. Doi: 10.1016/j.bmc.2011.09.039
Hornick A, Lieb A, Vo NP, Rollinger JM, Stuppner H, Prast H. The coumarin scopoletin potentiates acetylcholine release from synatposomes, amplifies hippocampal long-term potentiation and ameliorates anticholinergic- and age-impaired memory. Neuroscience, 2011, 197, 280-292. Doi: 10.1016/j.neuroscience.2011.09.006
Noha SM, Atanasov AG, Schuster D, Markt P, Fakhrudin N, Heiss EH, Schrammel O, Rollinger JM, Stuppner H, Dirsch VM, Wolber G. Discovery of a novel IKK-β inhibitor by ligand-based virtual screening techniques. Bioorganic & Medicinal Chemistry Letters, 2011, 21(1), 577-583. Doi: 10.1016/j.bmcl.2010.10.051
Pfisterer PH, Shen C, Nikolovska-Coleska Z, Schyschka L, Schuster D, Rudy A, Wolber G, Vollmar AM, Rollinger JM, Stuppner H. In silico discovery of acylated flavonol monorhamnosides from Eriobotrya japonica as natural, small-molecular weight inhibitors of XIAP BIR3. Bioorganic & Medicinal Chemistry, 2011, 19(2), 1002-1009. Doi: 10.1016/j.bmc.2010.10.046
Pieri V, Belancic A, Morales S, Stuppner H. Identification and Quantification of Major Steviol Glycosides in Stevia rebaudiana Purified Extracts by 1H NMR Spectroscopy. Journal of Agricultural and Food Chemistry, 2011, 59(9), 4378-4384. Doi: 10.1021/jf104922q
Pieri V, Stuppner H. Quantification of Cynaropicrin in Artichoke Leaf Extracts by 1H NMR Spectroscopy. Planta Medica, 2011, 77(15), 1756-1758. Doi: 10.1055/s-0030-1271083
Safer S, Tremetsberger K, Guo Y-P, Kohl G, Samuel MR, Stuessy TF, Stuppner H. Phylogenetic relationships in the genus Leontopodium (Asteraceae: Gnaphalieae) based on AFLP data. Botanical Journal of the Linnean Society, 2011, 165(4), 364-377. Doi: 10.1111/j.1095-8339.2011.01117.x
Safer S, Cicek SS, Pieri V, Schwaiger S, Schneider P, Wissemann V, Stuppner H. Metabolic fingerprinting of Leontopodium species (Asteraceae) by means of 1H NMR and HPLC-ESI-MS. Phytochemistry, 2011, 72(11-12), 1379-1389. Doi: 10.1016/j.phytochem.2011.04.006
Schuster D, Markt P, Grienke U, Mihaly-Bison J, Binder M, Noha SM, Rollinger JM, Stuppner H, Bochkov VN, Wolber G. Pharmacophore-based discovery of FXR agonists. Part I: Model development and experimental validation. Bioorganic & Medicinal Chemistry, 2011, 19/23, 7168-7180. Doi: 10.1016/j.bmc.2011.09.056
Schwaiger S, Zeller I, Poelzelbauer P, Frotschnig S, Laufer G, Messner B, Pieri V, Stuppner H, Bernhard D. Identification and pharmacological characterization of the anti-inflammatory principal of the leaves of dwarf elder (Sambucus ebulus L.). Journal of Ethnopharmacology, 2011, 133(2), 704-709. Doi: 10.1016/j.jep.2010.10.049
Waltenberger B, Rollinger JM, Griesser U, Stuppner H, Gelbrich T. Plumeridoid C from the Amazonian traditional medicinal plant Himatanthus sucuuba. Acta Crystallographic Section C, Crystal Structure Communications, 2011, 67/10, 409-412. Doi: 10.1107/S0108270111035761
Waltenberger B, Schuster D, Paramapjon S, Gritsanapan W, Wolber G, Rollinger JM, Stuppner H. Predicting cyclooxygenase inhibition by three-dimensional pharmacophoric profiling. Part II: Identification of enzyme inhibitors from Prasaplai, a Thai traditional medicine. Phytomedicine, 2011, 18(2-3), 119-133. Doi: 10.1016/j.phymed.2010.08.002
Waltenberger B, Wiechmann K, Bauer J, Markt P, Noha SM, Wolber G, Rollinger JM, Werz O, Schuster D, Stuppner H. Pharmacophore Modeling and Virtual Screening for Novel Acidic Inhibitors of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1). Journal of Medicinal Chemistry, 2011, 54(9), 3163-3174. Doi: 10.1021/jm101309g
2010
Aberham A, Cicek SS, Schneider P, Stuppner H. Analysis of Sesquiterpene Lactones, Lignans, and Flavonoids in Wormwood (Artemisia absinthium L.) Using High-Performance Liquid Chromatography (HPLC)-Mass Spectrometry, Reversed Phase HPLC, and HPLC-Solid Phase Extraction-Nuclear Magnetic Resonance. Journal of Agricultural and Food Chemistry, 2010, 58(20), 10817-10823. Doi: 10.1021/jf1022059
Antal DS, Schwaiger S, Ellmerer-Müller EP, Stuppner H. Cotinus coggygria wood: novel flavanone dimer and development of an HPLC/UV/MS method for the simultaneous determination of fourteen phenolic constituents. Planta Medica, 2010, 76(15), 1765-1772. Doi: 10.1055/s-0030-1249878
Baumgartner RR, Steinmann D, Heiss EH, Atanasov AG, Ganzera M, Stuppner H, Dirsch VM. Bioactivity-Guided Isolation of 1,2,3,4,6-Penta-O-galloyl-D-glucopyranose from Paeonia lactiflora Roots As a PTP1B Inhibitor. Journal of Natural Products, 2010, 73(9), 1578-1581. Doi: 10.1021/np100258e
Cicek SS, Khom S, Taferner B, Hering S, Stuppner H. Bioactivity-Guided Isolation of GABAA Receptor Modulating Constituents from the Rhizomes of Actaea racemosa. Journal of Natural Products, 2010, 73(12), 2024-2028. Doi: 10.1021/np100479w
Cicek SS, Schwaiger S, Ellmerer EP, Stuppner H. Development of a fast and convenient method for the isolation of triterpene saponins from Actaea racemosa by high-speed countercurrent chromatography coupled with evaporative light scattering detection. Planta Medica, 2010, 76(5), 467-473. Doi: 10.1055/s-0029-1186236
Fakhrudin N, Ladurner A, Atanasov AG, Heiss EH, Baumgartner L, Markt P, Schuster D, Ellmerer EP, Wolber G, Rollinger JM, Stuppner H, Dirsch VM. Computer-Aided Discovery, Validation, and Mechanistic Characterization of Novel Neolignan Activators of Peroxisome Proliferator-Activated Receptor γ. Molecular Pharmacology, 2010, 77(4), 559-566. Doi: 10.1124/mol.109.062141
Gao H, Zehl M, Kählig HP, Schneider P, Stuppner H, Banuls LMY, Kiss R, Kopp B. Rapid Structural Identification of Cytotoxic Bufadienolide Sulfates in Toad Venom from Bufo melanostictus by LC-DAD-MSn and LC-SPE-NMR. Journal of Natural Products, 2010, 73(4), 603-608. Doi: 10.1021/np900746k
Grienke U, Schmidtke M, Kirchmair J, Pfarr K, Wutzler P, Dürrwald R, Wolber G, Liedl KR, Stuppner H, Rollinger JM. Antiviral Potential and Molecular Insight into Neuraminidase Inhibiting Diarylheptanoids from Alpinia katsumadai. Journal of Medicinal Chemistry, 2010, 53(2), 778-786. Doi: 10.1021/jm901440f
Pfisterer PH, Wolber G, Efferth T, Rollinger JM, Stuppner H. Natural products in structure-assisted design of molecular cancer therapeutics. Current Pharmaceutical Design, 2010, 16(15), 1718-1741.
Pfisterer, P.H., Rollinger, J.M., Schyscka, L., Rudy, A., Vollmar, A.M., Stuppner H Neoandrographolide from Andrographis paniculata as a potential natural chemosensitizer. Planta Medica, 2010, 76(15), 1698-1700. Doi: 10.1055/s-0030-1249876
Schuster D, Kern L, Hristozov DP, Terfloth L, Bienfait B, Laggner C, Kirchmair J, Grienke U, Wolber G, Langer T, Stuppner H, Gasteiger J, Rollinger JM. Applications of integrated data mining methods to exploring natural product space for acetylcholinesterase inhibitors. Combinatorial Chemistry & High Throughput Screening, 2010, 13(1), 54-66. Doi: 10.2174/138620710790218212
Schuster D, Spetea M, Music M, Rief S, Fink M, Kirchmair J, Schütz J, Wolber G, Langer T, Stuppner H, Schmidhammer H, Rollinger JM. Morphinans and isoquinolines: Acetylcholinersterase inhibition, pharmacophore modeling, and interaction with opioid receptors. Bioorganic & Medicinal Chemistry, 2010, 18(14), 5071-5080. Doi: 10.1016/j.bmc.2010.05.071
Schuster D, Waltenberger B, Kirchmair J, Distinto S, Markt P, Stuppner H, Rollinger JM, Wolber G. Predicting cyclooxygenase inhibition by three-dimensional pharmacophoric profiling. Part I: model generation, validation and applicability in ethnopharmacology. Molecular Informatics, 2010, 29(1-2), 75-86. Doi: 10.1002/minf.200900071
Schwaiger S, Hehenberger S, Ellmerer EP, Stuppner H. A new Bisabolane Derivative of Leontopodium andersonii. Natural Product Communications, 2010, 5(5), 667-668.
Svejda B, Aguiriano-Moser V, Sturm S, Hoger H, Ingolic E, Siegl V, Stuppner H, Pfragner R. Anticancer activity of novel plant extracts from Trailliaedoxa gracilis (W. W. Smith & Forrest) in human carcinoid KRJ-I Cells. Anticancer Research, 2010, 30(1), 55-64.
2009
Assimopoulou AN, Sturm S, Stuppner H, Papageorgiou VP. Preparative isolation and purification of alkannin/shikonin derivatives from natural products by high-speed counter-current chromatography. Biomedical Chromatography, 2009, 23(2), 182-198. Doi: 10.1002/bmc.1101
Costa S, Schwaiger S, Cervellati R, Stuppner H, Speroni E, Guerra CM. In vitro evaluation of the chemoprotective action mechanisms of leontopodic acid against aflatoxin B1 and deoxynivalenol-induced cell damage. Journal of Applied Toxicology, 2009, 29(1), 7-14. Doi: 10.1002/jat.1372
Ganzera M, Nischang I, Siegl C, Senzenberger B, Svec F, Stuppner H. Application of MEKC and monolithic CEC for the analysis of bioactive naphthoquinones in Eleutherine americana. Electrophoresis, 2009, 30(21), 3757-3763. Doi: 10.1002/elps.200900247
Ganzera M, Sturm S, Stuppner H. Plant analysis – state of the art and future developments. Planta Medica, 2009, 75(7), 671-671. Doi: 10.1055/s-0029-1185603
Gumy C, Thurnbichler C, Aubry EM, Balasz Z, Pfisterer P, Baumgartner L, Stuppner H, Odermatt A, Rollinger JM. Inhibition of 11β-hydroxysteroid dehydrogenase type 1 by plant extracts used as traditional antidiabetic medicines. Fitoterapia, 2009, 80(3), 200-205. Doi: 10.1016/j.fitote.2009.01.009
Horak SB, Koschak A, Stuppner H, Striessnig J. Use-dependent block of voltage-gated Cav2.1 Ca2+ channels by petasins and eudesmol isomers. The Journal of Pharmacology and Experimental Therapeutics, 2009, 330(1), 220-226. Doi: 10.1124/jpet.109.151183
Pieri V, Schwaiger S, Ellmerer EP, Stuppner H. Iridoid Glycosides from the Leaves of Sambucus ebulus. Journal of Natural Products, 2009, 72(10), 1798-1803. Doi: 10.1021/np900373u
Reisinger U, Schwaiger S, Zeller I, Messner B, Stigler R, Wiedemann D, Mayr T, Seger C, Schachner T, Dirsch VM, Vollmar AM, Bonatti JO, Stuppner H, Laufer G, Bernhard D. Leoligin, the major lignan from Edelweiss, inhibits intimal hyperplasia of venous bypass grafts. Cardiovascular Research, 2009, 82(3), 542-549. Doi: 10.1093/cvr/cvp059
Rinner B, Li Zeng X, Haas H, Siegl V, Sturm S, Stuppner H, Pfragner R. Antiproliferative and Pro-apoptotic Effects of Uncaria tomentosa in Human Medullary Thyroid Carcinoma Cells. Anticancer Research, 2009, 29(11), 4519-4528.
Rollinger JM, Schuster D, Danzl B, Schwaiger S, Markt P, Schmidtke M, Gertsch J, Raduner S, Wolber G, Langer T, Stuppner H. In silico Target Fishing for Rationalized Ligand Discovery Exemplified on Constituents of Ruta graveolens. Planta Medica, 2009, 75(3), 195-204. Doi: 10.1055/s-0029-1202470
