SFB-F44 - Cell signaling in chronic CNS disorders
SFB Publications
2016
Wille A, Amort T, Singewald N, Sartori SB, Lusser A. (2016)
Dysregulation of select ATP-dependent chromatin remodeling factors in high trait anxiety.
Behav Brain Res. 2016 Sep 15;311:141-146. doi: 10.1016/j.bbr.2016.05.036.
Unger MS, Marschallinger J, Kaindl J, Höfling C, Rossner S, Heneka MT, Van der Linden A, Aigner L. (2016)
Early Changes in Hippocampal Neurogenesis in Transgenic Mouse Models for Alzheimer's Disease.
Mol Neurobiol. 2016 Oct;53(8):5796-806. doi: 10.1007/s12035-016-0018-9
Perez-Alcazar M, Culley G, Lyckenvik T, Mobarrez K, Bjorefeldt A, Wasling P, Seth H, Asztely F, Harrer A, Iglseder B, Aigner L, Hanse E, Illes S. (2016)
Human Cerebrospinal Fluid Promotes Neuronal Viability and Activity of Hippocampal Neuronal Circuits In Vitro.
Front Cell Neurosci. 2016 Mar 4;10:54. doi: 10.3389/fncel.2016.00054.
Rivera FJ, Kazanis I, Ghevaert C, Aigner L. (2016)
Beyond Clotting: A Role of Platelets in CNS Repair?
Front Cell Neurosci. 2016 Jan 20;9:511. doi: 10.3389/fncel.2015.00511.
Duda J, Poetschke C, Liss B (2016)
Converging roles of ion channels, calcium, metabolic stress, and activity pattern of substantia nigra dopaminergic neurons in health and Parkinson's disease.
J Neurochem, 139:156-178. doi: 10.1111/jnc.13572.
Härtner L, Keil TW, Kreuzer M, Fritz EM, Wenning GK, Stefanova N, Fenzl T. (2016)
Distinct Parameters in the EEG of the PLP α-SYN Mouse Model for Multiple System Atrophy Reinforce Face Validity.
Front Behav Neurosci. 2017 Jan 10;10:252. doi: 10.3389/fnbeh.2016.00252. eCollection 2016.
Benedetti B, Flucher BE et al: (2016)
Loss of the calcium chalcium channel (Beta)4 subunit impairs parallel fibre volley and Purkinje cell firing in Cerebellum of adult ataxic mice
ENJ, 2016 Jun;43(11):1486-98. PMID:27003325,PMCID: PMC4949674,DOI: 10.1111/ejn.13241
Fell B, Eckrich S, Blum K, Eckrich T, Hecker D, Obermair GJ, Münkner S, Flockerzi V, Schick B, Engel J. (2016)
α2δ2 Controls the Function and Trans-Synaptic Coupling of Cav1.3 Channels in Mouse Inner Hair Cells and Is Essential for Normal Hearing.
J Neurosci. 2016 Oct 26;36(43):11024-11036. 2016 Jun;43(11):1486-98. DOI: 10.1523/JNEUROSCI.3468-14.2016
Bachmann VA, Mayerhofer JE, Ilouz R, Tschaikner PM, Raffeiner P, Röck R, Courcelles M, Apelt F, Lu T, Baillie GS, Thibault P, Aanstad P, Stelzl U, Taylor SS, Stefan E (2016)
Gpr161 anchoring of PKA consolidates GPCR and cAMP signaling
Proc Natl Acad Sci USA. 2016 Jul 12;113(28):7786-91. PMID:27357676,PMCID: PMC4948347,DOI: 10.1073/pnas.1608061113
Brück D, Wenning GK, Stefanova N, Fellner L
Glia and alpha-synuclein in neurodegeneration: A complex interaction
Neurobiol Dis. 2016 Jan;85:262-74. PMID:25766679,PMCID:PMC4730552, DOI:10.1016/j.nbd.2015.03.003
Couillard-Despres S, Bieler L, Vogl M
Pathophysiology of traumatic spinal cord injury
Chap 19 in Neurological aspects of Spinal Cord Injury. Ed. N. Weidner, Springer 2016 in press
Daschil N, Humpel C (2016)
Green-Fluorescent Protein+ Astrocytes Attach to Beta-Amyloid Plaques in an Alzheimer Mouse Model and Are Sensitive for Clasmatodendrosis
Front. Aging Neurosci. 2016 Apr 8;8:75. PMID:27092076,PMCID:PMC4825400, DOI: 10.3389/fnagi.2016.00075
Fellner L, Kuzdas-Wood D, LevinJ, Ryazanov S, Leonov A, Giesinger C, Giese A, Wenning GK, Stefanova N (2016)
Anle128b Partly Ameliorates Motor Deficits Despite Failure of Neuroprotection in a Model of Advanced Multiple System Atrophy
Front Neurosci. 2016 Mar 10;10:99. PMID:27013960,PMCID:PMC4785146, DOI: 10.3389/fnins.2016.00099
Jaitner C, Reddy C, Abentung A, Whittle N, Rieder D, Delekate A, Korte M, Jain G, Fischer A, Sananbenesi F, Cera I, Singewald N, Dechant G, Apostolova G (2016)
Satb2 determines miRNA expression and long-term memory in the adult central nervous system
eLife 10.7554/eLife.17361
Kaser-Eichberger A, Schroedl F, Bieler L, Trost A, Bogner B, Runge C, Tempfer H, Zaunmair P, Kreutzer C, Traweer A, Reitsamer HA, Couillard-Despres S (2016)
Expression of lymphatic markers in the adult rat spinal cord
Front Cell Neurosci. 2016 Feb 9; 10:23. PMID:26903808,PMCID: PMC4746237, DOI: 10.3389/fncel.2016.00023
König R, Benedetti B, Rotheneichner P, O'Sullivan A, Kreutzer C, Belles M, Nacher J, Weiger TM, Aigner L, Couillard-Despres S
Distribution and fate of DCX/PSA-NCAM expressing cells in the adult mammalian Cortex: A local Reservoir for adult cortical neuroplasticity?
Front. Biol. 2016; 11(3): 193-213.
König R, Rotheneichner P, Marschallinger J, Aigner L, , Couillard-Despres S
Aging
Adult Neurogenesis in the Hippocampus. Ed. J Canales, Springer 2016. Chap 7
Mesirca P, Bidaud I, Briec F, Evain S, Torrente AG, Le Quang K, Leoni AL, Baudot M, Marger L, Chung You Chong A, et al (2016)
G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block
Proc Natl Acad Sci USA 113, E932-941
Ohn TL, Rutherford MA, Jing Z, Jung S, Duque-Afonso CJ, Hoch G, Picher MM, Scharinger A, Strenzke N, Moser T. (2016)
Hair cells use active zones with different voltage dependence of Ca2+ influx to decompose sounds into complementary neural codes.
PNAS 113, E4716–E4725.
Ortner NJ, Striessnig J
L-type calcium channels as drug targets in CNS disorders
Channels (Austin). 2016;10(1):7-13. PMID:26039257,PMCID: PMC4802752,DOI: 10.1080/19336950.2015.1048936
Pinggera A, Striessnig J (2016)
Cav 1.3 (CACNA1D) L-type Ca(2+) channel dysfunction in CNS disorders
J Physiol (Lond) 594, 5839–5849
Puschban Z, Sah A, Grutsch I, Singewald N, Dechant G (2016)
Reduced Anxiety-Like Behavior and Altered Hippocampal Morphology in Female p75NTR(exon IV-/-) Mice
Front Behav Neurosci. 2016 Jun 1;10:103. PMID:27313517 ,PMCID: PMC4887477, DOI: 10.3389/fnbeh.2016.00103
Sailer A, Scholz SW, Nalls MA, Schulte C, Federoff M, Price TR, Lees A, Roll OA, Dickson DW, Mok K, Mencacci NE, Schottlaender L, Chelban V, Ling H, O'Sullivan SS, Wood NW, Traynor BJ, Ferrucci L, Federoff HJ, Mhyre TR, Morris HR, Deuschl G, Quinn N, Widner H, Albanese A, Infante J, Bhatia KP, Poewe W, Oertel W, Höglinger GU, Wüllner U, Goldwurm S, Pellecchia MT, Ferreira J, Tolosa E, Bloem BR, Rascol O, Meissner WG, Hardy JA, Revez T, Holton JL, Gasser T, Wenning GK, Singleton AB, Houlden H, European Multiple System Atrophy, Study Group and the UK Multiple System Atrophy Study Group.
A genome-wide association study in multiple system atrophy.
Neurology, 2016 Oct 11;87(15):1591-1598. PMID:27629089,PMCID: PMC5067544 ,DOI: 10.1212/WNL.0000000000003221
Schafferer S, Khurana R, Refolo V, Venezia S, STurm E, Piatti P, Hechenberger C, Hackl H, Kessler R, Willi M, Gstir R, Krogsdam A, Lusser A, Poewe W, Wenning GK, Hüttenhofer A, Stefanova N (2016)
Changes in the miRNA-mRNA Regulatory Network Precede Motor Symptoms in a Mouse Model of Multiple System Atrophy: Clinical Implications
PLoS One. 2016 Mar 10;11(3):e0150705. PMID:26962858,PMCID: PMC4786272, DOI:10.1371/journal.pone.0150705
Sartori SB, Maurer V, Murphy C, Schmuckermair C, Muigg P, Neumann ID, Whittle N, Singewald N: (2016)
Combined Neuropeptide S and D-Cycloserine Augmentation Prevents the Return of Fear in Extinction-Impaired Rodents: Advatage of Dual versus Single Drug Approaches
Int J Neuropsychopharmacol, 2016 2016 Jun 1;19(6). pii: pyv128. doi: 10.1093/ijnp/pyv128. Print 2016 Jun., PMID:26625894PMCID:PMC4926792DOI:10.1093/ijnp/pyv128
Stanika R, Campiglio M, Pinggera A, Lee A, Striessnig J, Flucher BE, Obermair GJ (2016)
Splice variants of the Cav1.3 L-type calcium channel regulate dendritic spine morphology
SCi Rep. 2016 Oct 6;6:34528. PMID:27708393,PMCID: PMC5052568,DOI: 10.1038/srep34528
Stefanova N, Wenning GK (2016)
Review: Multiple System atrophy: emerging Targets for interventional therapies
Neuropathol Appl Neurobiol. 2016 Feb;42(1):20-32. PMID:26785838,PMCID: PMC4788141, DOI: 10.1111/nan.12304
Striessnig J (2016)
Voltage-gated calcium channels - from basic mechanisms to disease
J Physiol (Lond) 594, 5817–5821
Sturm E, Fellner L, Krismer F, Poewe W, Wenning DK, Stefanova N (2016)
Neuroprotection by Epigenetic Modulation in a Transgenic Model of Multiple System Atrophy
Neurotherapeutics. 2016 Oct;13(4):871-879. PMID:27259295,PMCID:PMC5081120,DOI: 10.1007/s13311-016-0447-1
Sultana N, Dienes B, Benedetti A, Tuluc P, Szentesi P, Sztretye M, Rainer J, Hess M.W., Schwarzer C, Obermair GJ, Csernoch L, Flucher BE (2016)
Restricting calcium currents is required for correct fiber type specification in skeletal muscle
Development. 2016 May 1;143(9):1547-59. PMID:26965373,PMCID:PMC4909858,DOI: 10.1242/dev.129676
Torrente AG., Mesirca P, Neco P, Rizzetto R, Dubel S, Barrere C, Sinegger-Brauns M, Striessnig J, Richard S, Nargeot J, et al (2016)
L-type Cav1.3 Channels Regulate Ryanodine Receptor-dependent Ca2+ Release during Sino-Atrial Node Pacemaker Activity
Cardiovasc Res
Tuluc P, Benedetti B, Coste de Bagneaux P, Grabner M, Flucher BE (2016)
Two distinct voltage-sensing domains control voltage sensitivity and kinetics of current activation in CaV1.1 calcium channels
J Gen Physiol. Jun;147(6):437-49. PMID:27185857,PMCID:PMC4886277, DOI: 10.1085/jgp.201611568
Tuluc P, Yarov-Yarovoy V, Benedetti B, Flucher BE (2016)
Molecular Interactions in the Voltage Sensor Controlling Gating Properties of CaV Calcium Channels
Structure. 2016 Feb 2;24(2):261-71. PMID:26749449,DOI: 10.1016/j.str.2015.11.011
Whittle N, Maurer V, Murphy C, Rainer J, Bindreither D, hausschild M, Scharinger A, Oberhauser M, Keil T, Brehm C, Valovka T, Striessnig J, Singewald N: (2016)
Enhancing dopaminergic signaling and histone acetylation promotes Long-term rescue of deficient fear extinction
Transl Psychiatry, 2016 Dec 6;6(12):e974. doi: 10.1038/tp.2016.231, PMID:27922638DOI:10.1038/tp.2016.231
Zussy C, Gómez-Santacana X, Rovira X, De Bundel D, Ferrazzo S, Bosch D, Asede D, Malhaire F, Acher F, Giraldo J, Valjent E, Ehrlich I, Ferraguti F, Pin J-P, Llebaria A, Goudet C (2016)
Dynamic modulation of chronic pain related behaviors by amygdala metabotropic glutamate receptor 4
Mol Psychiatry doi: 10.1038/mp.2016.223. [Epub ahead of print]
